Pharmaceutical compound zinc glycerolate complex prepared by reacting zinc oxide and glycerol
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
C01F-003/06
출원번호
US-0403636
(1982-06-20)
국제출원번호
PCT/AU81/00164
(1981-11-18)
§371/§102 date
[Act 371]19820720
([Act 101]19820720)
국제공개번호
WO82/01867
(1982-06-10)
발명자
/ 주소
Taylor, Reginald M.
Brock, Alan J.
대리인 / 주소
Cushman, Darby & Cushman
인용정보
피인용 횟수 :
12인용 특허 :
3
초록▼
A pharmaceutical compound with therapeutic, prophylactic and cosmetic properties for human and veterinary use, being a zinc glycerolate complex formed as a reaction product of zinc oxide and glycerol having a platy morphology with generally hexagonal crystals (1/2/3) of relatively low thickness and
A pharmaceutical compound with therapeutic, prophylactic and cosmetic properties for human and veterinary use, being a zinc glycerolate complex formed as a reaction product of zinc oxide and glycerol having a platy morphology with generally hexagonal crystals (1/2/3) of relatively low thickness and high lubricity, with or without further reaction products or carriers.
대표청구항▼
1. A pharmaceutical compound formed by the process of reacting zinc oxide with glycerol by raising the temperature to about 260° C. and maintaining the temperature until reaction is completed to form C 3 H 6 O 3 Zn, cooling the reaction mixture and pouring the zinc glycerolate slurry so formed into
1. A pharmaceutical compound formed by the process of reacting zinc oxide with glycerol by raising the temperature to about 260° C. and maintaining the temperature until reaction is completed to form C 3 H 6 O 3 Zn, cooling the reaction mixture and pouring the zinc glycerolate slurry so formed into water, adding copper to the said slurry and shaking to cause zinc to be replaced by the said copper, and filtering the residue and washing and drying to produce a modified zinc glycerolate complex. 2. The pharmaceutical compound according to claim 1 wherein the copper is added as an aqueous solution of a copper salt. 3. A composition formed by the process of reacting zinc oxide with glycerol by raising the temperature to about 260° C. and, maintaining the temperature until reaction is complete to form C 3 H 6 O 3 Zn, cooling the reaction mixture and pouring the slurry so formed into water, filtering, washing and drying to isolate zinc glycerolate, and blending into the zinc glycerolate and oleaginous substance for application of the blend to the skin as a therapeutic or prophylactic or cosmetic substance. 4. A composition according to claim 3 wherein the oleaginous substance is a mixture of glycerol monostearate, paraffin oil, lanolin, glycerol and stearic acid to produce a shaving cream, the mixture being further mixed with potassium hydroxide and water and blended with the zinc glycerolate complex. 5. A composition according to claim 3 wherein the oleaginous substance is oleic acid, peanut oil and lanolin mixed together and melted and applied to the zinc glycerolate while blending in calcium hydroxide solution to form a sun screen. 6. A pharmaceutical which is a mixture of a zinc glycerolate complex having the formula C 3 H 6 O 3 Zn formed as a reaction product of zinc oxide and glycerol at a temperature range between 120° and 300° C., having a platy morphology with generally hexagonal crystals of relatively low thickness and high lubricity and an oleaginous substance suitable for application to the skin as a therapeutic or prophylactic or cosmetic substance. 7. A pharamceutical according to claim 6 wherein the oleaginous substance is a mixture of glycerol monostearate, paraffin oil, lanolin, glycerol and stearic acid to produce a shaving cream, the mixture being further mixed with potassium hydroxide and water and blended with the zinc glycerolate complex. 8. A pharmaceutical according to claim 6 wherein the oleaginous substance is oleic acid, peanut oil and lanolin mixed together and melted and applied to the zine glycerolate while blending in calcium hydroxide solution to form a sun screen. 9. A method of applying a therapeutic or prophylactic or cosmetic material to the skin comprising applying to the skin a zinc glycerolate complex having the formula C 3 H 6 O 3 Zn formed as a reaction product of zinc oxide and glycerol at a temperature range between 120° and 300° C., having a platy morphology with generally hexagonal crystals of relatively low thickness and high lubricity. 10. A method according to claim 9 wherein the zinc glycerolate complex is formed by the process of reacting zinc oxide or zinc acetate with glycerol in the proportions of about 50 gms zinc oxide or zinc acetate to 500 gms glycerol, raising the temperature of the mix to about 260° C. and maintaining the temperature until reaction is completed, cooling and pouring the mixture so formed into water, filtering, washing and drying to isolate the zinc glycerolate complex. 11. A method of applying a therapeutic or prophylactic or cosmetic material to the skin comprising applying to the skin the composition of claim 1. 12. A method of applying a therapeutic or prophylactic or cosmetic material to the skin comprising applying to the skin a composition formed by the process of reacting zinc oxide with glycerol wherein a colouring dye is added to the zinc oxide before forming an admixture with the glycerol, raising the temperature of the mixture to about 260° C. and maintaining the temperature until reaction is completed to form C 3 H 6 O 3 Zn, cooling the reaction mixture and pouring the slurry so formed into water, filtering the residue and washing and drying to produce the coloured zinc glycerolate complex. 13. A method according to claim 12 wherein the dye is a mixture of certolake erythrosine and certolake tartrazine to produce a tan coloured zine glycerolate. 14. A method of applying a therapeutic or prophylactic or cosmetic material to the skin comprising applying to the skin the composition of claim 3. 15. A method according to claim 14 wherein the oleaginous substance is a mixture of glycerol monostearate, paraffin oil, lanolin, glyercol and stearic acid the mixture being further mixed with potassium hydroxide and water and blended with the zinc glycerolate complex to form a shaving cream. 16. A method according to claim 14 wherein the oleaginous substance is oleic acid, peanut oil and lanolin mixed together and melted and applied to the zinc glycerolate while blending in calcium hydroxide solution to form a sun screen. 17. A method of applying a therapeutic or prophylactic or cosmetic material to the skin comprising applying to the skin the composition of claim 6. 18. A method of applying a therapeutic or prophylactic or cosmetic material to the skin comprising applying to the skin the composition of claim 7. 19. A method of applying a therapeutic or prophylactic or cosmetic material to the skin comprising applying to the skin the composition of claim 8. 20. A compound according to claim 1 wherein the complex is prepared by reacting 80 to 100 parts by weight of zinc oxide or zinc acetate to 100 parts by weight of glycerol. 21. A composition formed by the process of reacting zinc oxide or zinc acetate with glycerol wherein a colouring dye is added to the zinc oxide or zinc acetate before forming an admixture with the glycerol, raising the temperature of the mixture to about 260° C. and maintaining the temperature until reaction is completed to form C 3 H 6 O 3 Zn, cooling the reaction mixture and pouring the slurry so formed into water, filtering the residue and washing and drying to produce the coloured zinc glycerolate complex there being employed 80 to 100 parts by weight of zinc oxide or zinc acetate to 1000 parts by weight of glycerol to the form the complex. 22. A composition according to claim 3 wherein the complex is prepared by reacting 80 to 100 parts by weight of zinc oxide or zinc acetate to 1000 parts by weight of glycerol. 23. A composition according to claim 6 wherein the complex is prepared by reacting 80 to 100 parts by weight of zinc oxide or zinc acetate to 1000 parts by weight of glycerol. 24. A method according to claim 9 wherein the complex is formed by reacting 80 to 100 parts by weight of zinc oxide or zinc acetate to 1000 parts by weight of glycerol.
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Staffier Dominic Thomas (19 Breed St. East Boston MA 02128) Shershow Samuel Louis (72 Lancaster Ave. Revere MA 02151) Norton William Barry (85 Longmeadow Road Norwood MA 02062), Composition for reducing bodily odor and perspiration.
Dutta, Partha S.; Lewis, Sarah L.; Litz, Kyle E.; Rossetti, Mark N.; Jordan, Tracey M.; Vreeland, Jennifer L., Metal alkoxides, apparatus for manufacturing metal alkoxides, related methods and uses thereof.
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