초록 ▼

The instant invention is directed to a bioerodible poly(ortho ester) thermoplastic elastomer prepared from: (A) a diketene diacetal; (B) a long-chain non-polar, flexible diol containing 4 to 22 carbon atoms; and (C) a diol selected from the group consisting of: (i) diols containing at least on

The instant invention is directed to a bioerodible poly(ortho ester) thermoplastic elastomer prepared from: (A) a diketene diacetal; (B) a long-chain non-polar, flexible diol containing 4 to 22 carbon atoms; and (C) a diol selected from the group consisting of: (i) diols containing at least one functional group which produces hydrogen bonding or other association, and (ii) rigid symmetrical diols.

대표청구항 ▼

1. A bioerodible poly(ortho ester) thermoplastic elastomer prepared from: (A) a diketene diacetal; (B) a long-chain non-polar, flexible diol containing 4 to 22 carbon atoms and (C) a diol containing at least one functional group which results in hydrogen bonding or other association selected fr

1. A bioerodible poly(ortho ester) thermoplastic elastomer prepared from: (A) a diketene diacetal; (B) a long-chain non-polar, flexible diol containing 4 to 22 carbon atoms and (C) a diol containing at least one functional group which results in hydrogen bonding or other association selected from the group consisting of amide, urethane, urea and imide groups. 2. The elastomer of claim 1 wherein said long-chain, non-polar, flexible diol is 1,10-decane diol. 3. The elastomer of claim 1 wherein said amide containing diol is an amide selected from the group consisting of N-(3-hydroxypropyl)-γ-hydroxybutyramide and N,N'-bis(2-hydroxyethyl)-terephthalamide. 4. A bioerodible poly(ortho ester thermoplastic elastomer prepared from: (A) 60 to 95%, by weight, based on the total weight of the polymer produced, of a flexible segment prepared from a diketene diacetal and a long chain, non-polar, flexible diol containing 4 to 22 carbon atoms; and (B) 5 to 40%, by weight, based on the total weight of the polymer produced, of a rigid segment prepared from a diketene diacetal and a rigid diol containing at least one functional group which results in hydrogen bonding or other association selected from the group consisting of amide, urethane, urea and imide groups.