초록 ▼

A composite package adapted for initially separately containing a dry medicament and a diluent therefor, the diluent containing package portion being a collapsible bag with an I.V. set fitment attachment port and an injection port, and a dry medicament containing receptacle container, the dry medica

A composite package adapted for initially separately containing a dry medicament and a diluent therefor, the diluent containing package portion being a collapsible bag with an I.V. set fitment attachment port and an injection port, and a dry medicament containing receptacle container, the dry medicament container including an open end cylinder sealingly engageably mountable in a top opening in the collapsible bag, the cylinder having an elastomeric bottom closure plug therein, a top plunger means constituting a top cylinder closure and a final seal for the container, the plunger being depressible within the cylinder, and operable to displace the bottom closure plug to open the cylinder bottom for discharge therefrom, and subsequent mixing of, the dry medicament in the diluent in the collapsible bag for subsequent disbursement of the mixture therefrom.

대표청구항 ▼

1. A multicompartment medicament container comprising a dry medicament compartment and a liquid diluent compartment, said compartments being discrete and separately selectively filled respectively with a dry medicament and a liquid diluent, said compartments being separately respectively inspectable

1. A multicompartment medicament container comprising a dry medicament compartment and a liquid diluent compartment, said compartments being discrete and separately selectively filled respectively with a dry medicament and a liquid diluent, said compartments being separately respectively inspectable for determining contents and conditions therein, said compartments being superposedly joined and thereby constituting a multicompartment container, said dry medicament compartment including a double open ended cylinder consisting of an inner glass material cylinder inert to said dry medicament and an outer plastic material cylinder, said plastic outer cylinder attached by sealing in an opening in said liquid diluent compartment and thereby forming said multicompartment medicament container assembly, a slidably removable bottom sealing and closure means in said inner glass cylinder, and plunger means operable for axial sliding movement therein from a first position adjacent one end of said inner cylinder to a second position at the opposite end of said inner cylinder directly communicating with said diluent compartment to expel said bottom sealing and closure means out through a bottom of said cylinder open end as an entity, for free displacement thereof into said diluent compartment, and complete discharge of the dry medicament through said bottom open end into said diluent for intermixing therewith. 2. A multicompartment medicament container as claimed in claim 1, said container comprising a two-compartment large volume I.V. container. 3. A container as claimed in claim 1, said open-ended cylinder comprising said dry medicament compartment being formed of a material non-reactive with a dry medicament therein, said removable bottom sealing and closure means comprising a plug of resilient material, resiliently engaged within said cylinder proximate the bottom thereof and adapted to support said dry medicament, an upper plunger and sealing disc in said cylinder spaced above said bottom plug, and forming therebetween said dry medicament compartment, said disc being selectively depressible and thereby operable to compress gaseous medium within said compartment and to dislodge said bottom closure and sealing plug from said cylinder. 4. A container as claimed in claim 3, said upper plunger sealing disc having an extended stem and an actuating top member thereon and being adapted for downward displacement for depressing said upper plunger sealing disc for sliding displacement of said bottom closure and sealing plug through said bottom open cylinder end. 5. A container as claimed in claim 1, said glass and said plastic cylinders respectively having top outwardly extending flanges thereon, a sealing gasket interposed between said flanges and seal means crimped about the top flanges for sealingly maintaining said sleeves joined. 6. A container as claimed in claim 1, wherein said liquid diluent compartment comprises a flexible and transparent I.V. type bag, said bag having an upper opening, said dry medicament compartment being insertable in and sealable in said opening, said bag further including a bottom addition port and a bottom spike receiving port for intravenous system connections.