초록 ▼

An applicator for the electrophoretic deposition of a medicament through or on a skin surface. The device consists of layers of a reservoir containing the drug, a battery layer superimposed on the reservoir, and a cover of electrically conductive material fully enclosing the layers and having a lip

An applicator for the electrophoretic deposition of a medicament through or on a skin surface. The device consists of layers of a reservoir containing the drug, a battery layer superimposed on the reservoir, and a cover of electrically conductive material fully enclosing the layers and having a lip along its periphery to engage the skin surface. An electrically conductive adhesive bonds the lip of the cover to the skin.

대표청구항 ▼

1. An applicator for the migration of medicament through the skin into the blood stream of a patient comprising: reservoir means for containing said medicament, battery means for supplying a charge for the medicament and being adjacent one side of said reservoir means with the side of said battery m

1. An applicator for the migration of medicament through the skin into the blood stream of a patient comprising: reservoir means for containing said medicament, battery means for supplying a charge for the medicament and being adjacent one side of said reservoir means with the side of said battery means facing said reservoir means for charging the medicament, means for covering comprising an electrically conductive material for partially enclosing said battery means and said reservoir means leaving the side of said reservoir means opposite that of said battery means exposed for contacting said skin, means for electrically connecting the battery means to the cover means, said cover means having a lip defining the periphery of said applicator for making contact with said skin when mounted on said skin leaving said battery means and reservoir means fully enclosed, and electrically conductive adhesive material coating disposed on the underside of said lip, whereby when said applicator is mounted on said skin a complete electrical circuit through said skin is formed and the medicament in said reservoir means migrates out of said reservoir means and through said skin into the blood steam of said patient. 2. The applicator of claim 1 in which said reservoir means is made from a microporous material whereby said medicament provides an electrical path therethrough. 3. The applicator of claim 2 said covering an reservoir means being conformable to the shape of said skin. 4. The applicator of claim 3 having a semipermeable membrane within said cover means on the side of said reservoir means facing said skin. 5. The applicator of claim 4 having means within said cover means for electrically insulating the latter from said reservoir means. 6. The applicator of claim 2 said circuit having means to maintain constant current flow during the period said medicament is being delivered. 7. The applicator of claim 6 said circuit having means to terminate deposition of said medicament after a predetermined quantity of medicament is delivered. 8. The applicator of claim 7 in which the last named means is a reverse plating cell.