|국가/구분||United States(US) Patent 등록|
|미국특허분류(USC)||528/361; 435/135; 528/496|
|발명자 / 주소|
|출원인 / 주소|
|대리인 / 주소||
|인용정보||피인용 횟수 : 33 인용 특허 : 4|
A continuous process for the extraction of 3-hydroxybutyrate polymers from micro-organism cells wherein a non-solvent is added to the extracted syrup to permit separation of the polymer and, by distillation, the bulk of the extraction liquid, which may be a solvent/non-solvent mixture, is recovered for re-use. Preferably the non-solvent added to the syrup is also recovered in the distillation.
1. A continuous, or cyclic batch, process for the extraction of a 3-hydroxybutyrate (HB) polymer from dried, solvent-permeable HB-polymer containing microorganism cells, said process comprising: (a) contacting said cells with an extraction liquid to form a syrup containing HB-polymer dissolved in the extraction liquid, said extraction liquid consisting of a mixture of (i) a solvent for said HB-polymer selected from dichloromethane, chloroform, and 1,2-dichloroethane, and (ii) a non-solvent for said HB polymer selected from methanol and ethanol, with...