초록 ▼

A synthetic resin wound dressing (e.g., a burn wound dressing) is disclosed consisting essentially of a polymer, such as poly(2-hydroxyethylmethacrylate), referred to as PHEMA, an organic solvent, such as polyethylene glycol (PEG), and a hydrogen binding plasticizer, such as dimethylsulfoxide (DMSO)

A synthetic resin wound dressing (e.g., a burn wound dressing) is disclosed consisting essentially of a polymer, such as poly(2-hydroxyethylmethacrylate), referred to as PHEMA, an organic solvent, such as polyethylene glycol (PEG), and a hydrogen binding plasticizer, such as dimethylsulfoxide (DMSO). The plasticizer regulates the set-up time of the synthetic resin so that the more plasticizer present, the shorter the set-up time. The dressing may be applied to the wound site in the form of a paste for the in situ curing or setting thereof, or the dressing may be preformed and then applied to the wound site. A variety of drug agents (e.g., silver sulfadiazine) may be incorporated in the synthetic resin so as to result in the time released administration of the drug agent to the area of the skin (e.g., a burn wound site or the like) covered by the wound dressing. A method of treatment using this dressing is also disclosed.

대표청구항 ▼

A synthetic resin wound dressing of the bonding type comprising a particulate, hydrophilic, water swellable polymer of an acrylate or acrylamide, an inert, non-toxic water miscible organic solvent of polyethylene glycol, the improvement which comprises, a hydrogen bonding plasticizer mixed with said

A synthetic resin wound dressing of the bonding type comprising a particulate, hydrophilic, water swellable polymer of an acrylate or acrylamide, an inert, non-toxic water miscible organic solvent of polyethylene glycol, the improvement which comprises, a hydrogen bonding plasticizer mixed with said polymer and solvent, said plasticizer is a material selected from the group consisting of dimethylsulfoxide, dimethylphthalate, 2,3-butylene carbonate, dimethylformamide, dimethyltetramethylene sulfone, diethylsulfone, methylene glycolate, methylpropyl sulfone, and butyrolactone, said polymer ranging between 30%-55% by weight of said dressing, with said solvent ranging between about 20%-60% by weight of said dressing, and said plasticizer ranging up to about 20% by weight of said dressing.