초록 ▼

A drug delivery system is provided which is in the form of hydrogel beads employed in a new interpenetrating polymer network which is formed by swelling hydrogel beads with an acrylic swelling agent and reacting the swelling agent with a cross-linking agent. The drug delivery system has superior dru

A drug delivery system is provided which is in the form of hydrogel beads employed in a new interpenetrating polymer network which is formed by swelling hydrogel beads with an acrylic swelling agent and reacting the swelling agent with a cross-linking agent. The drug delivery system has superior drug loading capacity and controlled release characteristics.

대표청구항 ▼

An interpenetrating polymer network drug delivery system comprised of a hydrogel polymer interpendetrated by and interwoven with a diffusion rate controlling membrane formed of a cross-linked polymer consisting essentially of the reaction product of a swelling agent which is acrylic acid, methyl met

An interpenetrating polymer network drug delivery system comprised of a hydrogel polymer interpendetrated by and interwoven with a diffusion rate controlling membrane formed of a cross-linked polymer consisting essentially of the reaction product of a swelling agent which is acrylic acid, methyl methacrylate, acrylic anhydride, ethylene-vinyl acetate, hydroxyehtyl acrylate, methyl acrylate, vinyl pryidine, vinyl chloride, methacrylic acid, acrylamide, hydroxy propyl methacrylate, hydroxyethyl methacrylate, butyl acrylate or mixtures thereof and a cross-linking agent which is butylene diacrylate, ethylene diemthacrylate, divinyl benzene, ethylene glycol dimethacrylate, tetraethylene glycol dimethacrylate or methyl bisacrylamide.