초록 ▼

An improved clot activator system for reducing the clotting time for blood samples in serum separation tubes, and the like, as well as increasing the degree of clotting, while at the same time, reducing the cost of production. This is achieved by the addition of glass pieces to the tube which pieces

An improved clot activator system for reducing the clotting time for blood samples in serum separation tubes, and the like, as well as increasing the degree of clotting, while at the same time, reducing the cost of production. This is achieved by the addition of glass pieces to the tube which pieces are formed in a particular way by a sol-gel process. The particles are pieces of glass, and are a porous substantially rigid amorphous inorganic sponge with substantial reactive surfaces. When a blood sample is introduced into a serum separation tube containing such pieces, the blood enters the interstices of the pieces causing fragmentation thereof, which fragmentation causes sound and shock waves which, in turn, enhance the clotting of the blood.

대표청구항 ▼

A process for producing and utilizing a blood clot activator material, characterized by the steps of (a) forming a mixture by admixing ethylsilicate and ethyl alcohol; (b) initiating hydrolysis of the mixture formed from said forming step by adding a reactant selected from the group consisting of am

A process for producing and utilizing a blood clot activator material, characterized by the steps of (a) forming a mixture by admixing ethylsilicate and ethyl alcohol; (b) initiating hydrolysis of the mixture formed from said forming step by adding a reactant selected from the group consisting of ammonia, acetic acid, sulphuric acid, and hydrochloric acid; (c) partially hydrolyzing said mixture from said adding step, by introducing therein less than a stoichiometric quantity of water; (d) maintaining in a first maintaining step said mixture from said partial hydrolysis step at room temperature while stirring for a period of time sufficient to polymerize said ethylsilicate into a solidified form of glass; (e) maintaining in a second maintaining step said solidified glass obtained from said first maintaining step at room temperature for a period of time sufficient to dry said solidified glass; (f) maintaining in a third maintaining step said solidified glass from said second maintaining step at an elevated temperature within the range of between about 110°C. and 120°C. to break down said solidified glass into small pieces; and (g) introducing a quantity of said small pieces from said third maintaining step into each of a plurality of blood collection containers; (h) whereby blood samples subsequently introduced into said plurality of blood collection containers are caused to clot.