$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

Transdermal administration of fentanyl and device therefor 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A01N-025/24
  • A61K-009/70
출원번호 US-0633762 (1984-07-23)
발명자 / 주소
  • Gale Robert M. (Los Altos CA) Goetz Victor (Palo Alto CA) Lee Eun S. (Redwood City CA) Taskovich Lina T. (Palo Alto CA) Yum Su I. (Los Altos CA)
출원인 / 주소
  • Alza Corporation (Palo Alto CA 02)
인용정보 피인용 횟수 : 308  인용 특허 : 5

초록

Transdermal delivery systems for delivery of fentanyl and its analgetically effective derivatives for extended periods of time are disclosed which deliver the base form of the drug at a rate of from 0.5 to 10 m2/hr for a substantial portion of their useful life. The systems can be from 5-100 cm2 in

대표청구항

A process for inducing and maintaining analgesia which comprises administering through an area of intact skin, a skin permeable form of a material selected from the group consisting of fentanyl and its analgetically effective derivatives at an analgetically effective rate and continuing the administ

이 특허에 인용된 특허 (5)

  1. Capetola, Robert J.; McGuire, John L., Analgesic composition.
  2. Campbell, Patricia S.; Chandrasekaran, Santosh K., Dosage for coadministering drug and percutaneous absorption enhancer.
  3. Urquhart John (Palo Alto CA) Chandrasekaran Kumar (Palo Alto CA) Shaw Jane (Atherton CA), Method and therapeutic system for administering scopolamine transdermally.
  4. Chandrasekaran Santosh Kumar (Palo Alto CA) Urquhart John (Palo Alto CA) Shaw Jane Elizabeth (Atherton CA), Method and therapeutic system for providing chemotherapy transdermally.
  5. Wong ; Patrick S. L. ; Smith ; Kelly L. ; Michaels ; Alan S., Therapeutic systems made from certain segmented copolyesters.

이 특허를 인용한 특허 (308)

  1. Anderson, Carter R.; Morris, Russell L., Abuse potential reduction in abusable substance dosage form.
  2. Anderson, Carter R.; Morris, Russell L., Abuse potential reduction in abusable substance dosage form.
  3. Anderson, Carter R.; Morris, Russell L., Abuse potential reduction in abusable substance dosage form.
  4. Matthews, Frank; Boehm, Garth; Tang, Lijuan; Liang, Alfred, Abuse-deterrent multi-layer pharmaceutical composition comprising an opioid antagonist and an opioid agonist.
  5. Matthews, Frank; Boehm, Garth; Tang, Lijuan; Liang, Alfred, Abuse-deterrent multi-layer pharmaceutical composition comprising an opioid antagonist and an opioid agonist.
  6. Smith,David; Johns,Owen L., Adhesive attachment and removal device.
  7. Akemi, Hitoshi; Ninomiya, Kazuhisa; Kuroda, Hidetoshi; Matsuoka, Kensuke; Saeki, Yuji; Nishimura, Masato, Adhesive material and adhesive preparation.
  8. Ito, Takeshi; Tateishi, Tetsuro; Higo, Naruhito, Adhesive patch for fentanyl administration.
  9. Honma, Sachiko; Tateishi, Tetsuro, Adhesive preparation.
  10. Saeki, Yuji; Nishimura, Masato; Matsuoka, Kensuke; Muraoka, Takateru; Hosaka, Yoshifumi; Hori, Mitsuhiko; Ninomiya, Kazuhisa; Akemi, Hitoshi; Kuroda, Hidetoshi, Adhesive preparation containing fentanyl.
  11. Boer,F. Peter; Kupper,Robert, Analogs and prodrugs of buprenorphine.
  12. Nguyen, Anthony T., Clip advancer.
  13. Huitema, Thomas; Koch, Jr., Robert; Fuchs, Richard; Molitor, Nicholas, Clip advancer mechanism with alignment features.
  14. Nguyen, Anthony T.; Herrera-Davis, Denzel Z., Clip advancer with lockout mechanism.
  15. Nguyen, Anthony T.; Herrera-Davis, Denzel Z., Clip advancer with lockout mechanism.
  16. Parihar, Shailendra K., Clip applier adapted for use with a surgical robot.
  17. Parihar, Shaliendra, Clip applier adapted for use with a surgical robot.
  18. Huitema, Thomas W.; Davison, Mark A.; Koch, Jr., Robert L., Clip applier configured to prevent clip fallout.
  19. Huitema, Thomas; Davison, Mark; Koch, Jr., Robert, Clip applier configured to prevent clip fallout.
  20. Huitema, Thomas W., Clip applier with migrational resistance features.
  21. Huitema, Thomas W., Clip applier with migrational resistance features.
  22. Huitema, Thomas W., Clip applier with migrational resistance features.
  23. Pedersen, Ninfa Rangel; Palle, Steen, Colostrum composition.
  24. Ross, Russell Frederick, Composite microneedle array including nanostructures thereon.
  25. Ross, Russell Frederick, Composite microneedle array including nanostructures thereon.
  26. Holladay Leslie A. ; Treat-Clemons Lynda G. ; Bassett Patricia Margaret, Composition and method for enhancing electrotransport agent delivery.
  27. Brown,Teletha A.; Osborne,James; Rudella,Michael; Hunt,Brian; Malik,Vinod, Compositions and medical device for transdermal delivery of a drug and methods of making and using same.
  28. Hale Ron L. (Woodside CA) Lu Amy (Los Altos CA) Solas Dennis (San Francisco CA) Selick Harold E. (Belmont CA) Oldenburg Kevin R. (Fremont CA) Zaffaroni Alejandro C. (Atherton CA), Compositions and methods for enhanced drug delivery.
  29. Bozik, Michael E.; Petzinger, Jr., Thomas; Mather, James L.; Archibald, Donald, Compositions and methods for treating amyotrophic lateral sclerosis in responders.
  30. Bozik, Michael E.; Petzinger, Jr., Thomas; Mather, James L.; Archibald, Donald, Compositions and methods for treating amyotrophic lateral sclerosis in responders.
  31. Bozik, Michael E.; Dworetzky, Steven, Compositions and methods for treating chronic urticaria.
  32. Bozik, Michael E; Dworetzky, Steven, Compositions and methods for treating chronic urticaria.
  33. Bozik, Michael E.; Hebrank, Gregory; Farwell, Wildon; Petzinger, Jr., Thomas; Dworetzky, Steven, Compositions and methods for treating conditions related to increased eosinophils.
  34. Bozik, Michael E.; Dworetzky, Steven, Compositions and methods for treating plasma cell disorders and B-cell prolymphocytic disorders.
  35. Bozik, Michael E.; Dworetzky, Steven, Compositions and methods for treating plasma cell disorders and B-cell prolymphocytic disorders.
  36. Stanley Theodore H. (Salt Lake City UT) Hague Brian (West Valley UT), Compositions and methods of manufacture of compressed powder medicaments.
  37. Bozik, Michael E.; Gribkoff, Valentin; Petzinger, Jr., Thomas, Compositions and methods of using (R)-pramipexole.
  38. Bozik, Michael E.; Petzinger, Jr., Thomas; Gribkoff, Valentin, Compositions and methods of using (R)-pramipexole.
  39. Bozik, Michael E.; Petzinger, Jr., Thomas; Gribkoff, Valentin, Compositions of R(+) and S(−) pramipexole and methods of using the same.
  40. Bozik, Michael E.; Petzinger, Jr., Thomas; Gribkoff, Valentin, Compositions of R(+) and S(−) pramipexole and methods of using the same.
  41. Palmgren, Michael G.; Buch-Pedersen, Morten; Pedersen, Bjørn Pañella; Nissen, Poul, Crystal structure of a plasma membrane proton pump.
  42. White, Bradley E.; Hayter, Paul; Lemke, John; Satre, Scot; Chen, Corinna X.; Read, Brian W.; Dougherty, Jason E., Current control for electrotransport drug delivery.
  43. White, Bradley E.; Hayter, Paul; Lemke, John; Satre, Scot; Chen, Corinna X.; Read, Brian W.; Dougherty, Jason E., Current control for electrotransport drug delivery.
  44. Horiuchi Tetsuo (Osaka JPX) Inoue Yuichi (Osaka JPX), Dermal bandage and dermal preparation.
  45. Trautman,Joseph C.; Cormier,Michel J. N.; Eng,Kellee; Lin,Wei Qi; Kim,Hyunok L.; Sendelbeck,Sara L.; Neukermans,Armand P.; Edwards,Bruce P.; Lim,Wai Loong; Poutiatine,Andrew I.; Gyory,J. Richard, Device and method for enhancing skin piercing by microprotrusions.
  46. Theeuwes, Felix; Cormier, Michel J. N.; Neukermans, Armand P., Device and method for enhancing transdermal agent flux.
  47. Ross, Russell Frederick, Device for delivery of rheumatoid arthritis medication.
  48. Ross, Russell Frederick, Device for delivery of rheumatoid arthritis medication.
  49. Trautman Joseph Creagan ; Cormier Michel J. N. ; Kim Hyunok Lynn ; Zuck Michael G., Device for enhancing transdermal agent flux.
  50. Trautman Joseph Creagan ; Wong Patrick S.-L. ; Daddona Peter E. ; Kim Hyunok Lynn ; Zuck Michael G., Device for enhancing transdermal agent flux.
  51. Trautman, Joseph Creagan; Kim, Hyunok Lynn, Device for enhancing transdermal agent flux.
  52. Zuck Michael G., Device for enhancing transdermal agent flux.
  53. Mary Southam ; Keith J. Bernstein ; Henk Noorduin NL, Device for transdermal electrotransport delivery of fentanyl and sufentanil.
  54. Southam Mary ; Bernstein Keith J. ; Noorduin Henk,NLX, Device for transdermal electrotransport delivery of fentanyl and sufentanil.
  55. Southam, Mary; Bernstein, Keith J.; Noorduin, Henk, Device for transdermal electrotransport delivery of fentanyl and sufentanil.
  56. Southam,Mary; Bernstein,Keith J.; Noorduin,Henk, Device for transdermal electrotransport delivery of fentanyl and sufentanil.
  57. Southam,Mary; Bernstein,Keith J.; Noorduin,Henk, Device for transdermal electrotransport delivery of fentanyl and sufentanil.
  58. Johnson, Randolph Mellus; Theeuwes, Felix, Devices and methods for pain management.
  59. Johnson, Randolph Mellus; Theeuwes, Felix, Devices and methods for pain management.
  60. Cleary Gary W. (San Mateo CA), Diffusion matrix for transdermal drug administration and transdermal drug delivery devices including same.
  61. Enscore David J. ; Campbell Patricia S. ; Nedberge Diane ; Frame Richard D., Drug delivery devices and process of manufacture.
  62. Enscore David J. ; Campbell Patricia S. ; Nedberge Diane ; Frame Richard D., Drug delivery devices and process of manufacture.
  63. Choi, Young Kweon; Yu, Hyun Suk; Yoon, Hye Jeong; Kim, Ho Chin, Dual adhesive transdermal drug delivery system.
  64. McNichols, Larry A.; Phipps, Joseph B.; Lattin, Gary A.; Badzinski, John D.; Reining, Wiliam N.; Haak, Ronald P., Electrotransport delivery device having improved safety and reduced abuse potential.
  65. McNichols,Larry A.; Badzinski,John D.; Reining,William N.; Lattin,Gary A.; Haak,Ronald P; Phipps,Joseph B., Electrotransport delivery device having improved safety and reduced abuse potential.
  66. Huang, Haiyong Hugh, Encased tamper resistant controlled release dosage forms.
  67. Huang, Haiyong Hugh, Encased tamper resistant controlled release dosage forms.
  68. Huang, Haiyong Hugh, Encased tamper resistant controlled release dosage forms.
  69. Huang, Haiyong Hugh, Encased tamper resistant controlled release dosage forms.
  70. Huang, Haiyong Hugh, Encased tamper resistant controlled release dosage forms.
  71. Huang, Haiyong Hugh, Encased tamper resistant controlled release dosage forms.
  72. Grarup, Jesper; Nielsen, Hanne Wulf, Fentanyl composition for nasal administration.
  73. Grarup, Jesper; Nielsen, Hanne Wulf, Fentanyl composition for nasal administration.
  74. Grarup, Jesper; Nielsen, Hanne Wulf, Fentanyl composition for nasal administration.
  75. Miller, II, Kenneth J.; Govil, Sharad K.; Bhatia, Kuljit Singh, Fentanyl suspension-based silicone adhesive formulations and devices for transdermal delivery of fentanyl.
  76. Miller, II, Kenneth J.; Govil, Sharad K.; Bhatia, Kuljit Singh, Fentanyl suspension-based silicone adhesive formulations and devices for transdermal delivery of fentanyl.
  77. Matsushita, Kunihiko; Naruse, Mamoru; Hattori, Kenichi, Fentanyl-containing patch for external use.
  78. Williams, Simon F., Flushable disposable polymeric products.
  79. Huitema, Thomas W.; Bertke, Brian D.; Koch, Jr., Robert L.; Vitali, Dario; Molitor, Nicholas G., Force limiting mechanism for medical instrument.
  80. Gale, Robert M.; Nelson, Melinda K.; Cormier, Michel J. N.; Gupta, Suneel K.; Campbell, Patricia S., Formulations for the administration of fluoxetine.
  81. Gale,Robert M.; Nelson,Melinda K.; Cormier,Michel J. N.; Gupta,Suneel K.; Campbell,Patricia S., Formulations for the administration of fluoxetine.
  82. van Osdol, William W.; Crisologo, Nieves M.; Yum, Su Il, Formulations for the transdermal administration of fenoldopam.
  83. van Osdol, William W.; Crisologo, Nieves M.; Yum, Su Il, Formulations for the transdermal administration of fenoldopam.
  84. Yum Su I ; Nelson Melinda K. ; Campbell Patricia S., Formulations for transdermal delivery of pergolide.
  85. Yum, Su Il; Nelson, Melinda K.; Campbell, Patricia S., Formulations for transdermal delivery of pergolide.
  86. Qi, Xiaoyang, Fusogenic properties of saposin C and related proteins and peptides for application to transmembrane drug delivery systems.
  87. Fowler, William; Anderson, Clayton; Anderson, Carter, General medication disposal system.
  88. Nuwayser,Elie S., High drug loaded injectable microparticle compositions and methods of treating opioid drug dependence.
  89. Audett, Jay; Wen, Jianye; Goldman, Eli J.; Gale, Robert M.; Luciano, Allison; Foreman, Paul B.; Silverberg, Eric N., High enhancer-loading polyacrylate formulation for transdermal applications.
  90. Audett, Jay; Wen, Jianye; Goldman, Eli J.; Gale, Robert M.; Luciano, Allison; Foreman, Paul B.; Silverberg, Eric N., High enhancer-loading polyacrylate formulation for transdermal applications.
  91. Johnson, Randolph Mellus; Theeuwes, Felix; Gillis, Edward M.; Litmanovitz, Dana; Laidlaw, Barbara; Brown, James; Culwell, John; Filice, James A.; Wickman, Peter; Yum, Su-Il; Poutiatine, Andrew; Dinka, Implantable devices and methods for treatment of pain by delivery of fentanyl and fentanyl congeners.
  92. Landrau Felix A. ; Nedberge Diane E. ; Hearney Linda Mary, Incorporating poly-N-vinyl amide in a transdermal system.
  93. Ross, Russell Frederick, Injection molded microneedle array and method for forming the microneedle array.
  94. Green, Philip G.; Pettis, Ronald J.; Brosnan-Cook, Michelle R., Iontophoretic devices.
  95. Mohr Judy M. (Menlo Park CA) Baker Richard W. (Palo Alto CA) Nakaji Lisa A. (San Jose CA), Liquid reservoir transdermal patch for the administration of ketorolac.
  96. Jackson, Kristin; Miller, II, Kenneth James, Long-wearing removable pressure sensitive adhesive.
  97. Jackson, Kristin; Miller, II, Kenneth James, Long-wearing removable pressure sensitive adhesive.
  98. Hyatt Gary F. ; Bostic William M., Medical applicator and method.
  99. Williams, Simon F.; Martin, David P.; Skraly, Frank A., Medical devices and applications of polyhydroxyalkanoate polymers.
  100. Rizk, Said; Martin, David P.; Ho, Kicherl; Williams, Simon F., Medical devices containing oriented films of poly-4-hydroxybutyrate and copolymers.
  101. Ross, Russell Frederick, Medical devices for delivery of siRNA.
  102. Ross, Russell Frederick, Medical devices for delivery of siRNA.
  103. Anderson, Carter R.; Morris, Russell L., Medication disposal system.
  104. Phipps, Joseph B.; Southam, Mary; Bernstein, Keith J.; Noorduin, Henk, Method and device for transdermal electrotransport delivery of fentanyl and sufentanil.
  105. Southam Mary ; Bernstein Keith J. ; Noorduin Henk,NLX, Method and device for transdermal electrotransport delivery of fentanyl and sufentanil.
  106. Ross, Russell Frederick, Method for increasing the permeability of an epithelial barrier.
  107. Caldwell Larry J. (4146 Cranford Cir. San Jose CA 95124) Galer Bradley Stuart (7409 Woodlawn Ave. NE Seattle WA 98115), Method for treating headache pain with topical local anesthetic compositions.
  108. Osborne James L. (2365 Thompson Ct. Mountain View CA 94043) Nelson Melinda K. (1127 Hollenbeck Sunnyvale CA 94087) Enscore David J. (18291 Montpere Way Saratoga CA 95070) Yum Su I. (1021 Runnymead Ct, Method of administering nicotine transdermally.
  109. Levy Gerhard (Williamsville NY) Southam Mary (Portola Valley CA) Powers Cramer Marilou S. (Redwood CA), Method of fentanly administration for postoperative pain relief.
  110. Audett, Jay; Wen, Jianye; Goldman, Eli J.; Gale, Robert M.; Luciano, Allison; Foreman, Paul B.; Silverberg, Eric N., Method of making a high enhancer-loading polyacrylate formulation for transdermal applications.
  111. Martin, David P.; Rizk, Said; Ahuja, Ajay; Williams, Simon F., Method of making a medical textile from polyhydroxyalkanoate fibers.
  112. Rizk, Said, Method of making a polyhydroxyalkanoate filament.
  113. Reder Robert F. ; Goldenheim Paul D. ; Kaiko Robert F., Method of providing sustained analgesia with buprenorphine.
  114. Reder, Robert F.; Goldenheim, Paul D.; Kaiko, Robert F., Method of providing sustained analgesia with buprenorphine.
  115. Reder, Robert F.; Kaiko, Robert F.; Goldenheim, Paul D., Method of providing sustained analgesia with buprenorphine.
  116. Reder, Robert F.; Kaiko, Robert F.; Goldenheim, Paul D., Method of providing sustained analgesia with buprenorphine.
  117. Robert F. Reder ; Robert F. Kaiko ; Paul D. Goldenheim, Method of providing sustained analgesia with buprenorphine.
  118. Reder, Robert F.; Kaiko, Robert F.; Goldenheim, Paul D., Method of providing sustained analgesia with buprenorpine.
  119. Galer Bradley S. ; Caldwell Larry J., Method of treating neuroma pain.
  120. Stanley Theodore H. (Salt Lake City UT) Haque Brian (West Valley City UT), Methods and compositions for noninvasive administration of sedatives, analgesics, and anesthetics.
  121. Stanley Theodore H. (Salt Lake City UT) Hague Brian (West Valley City UT), Methods and compositions for noninvasive dose-to-effect administration of drugs with cardiovascular or renal vascular ac.
  122. Herschkowitz, Samuel; Fein, Seymour, Methods and devices for desmopressin drug delivery.
  123. Herschkowitz, Samuel; Fein, Seymour H., Methods and devices for desmopressin drug delivery.
  124. Klein, Bjarke Mimer; Norgaard, Jens Peter; Shumel, Brad, Methods comprising desmopressin.
  125. Klein, Bjarke Mirner; Norgaard, Jens Peter, Methods comprising desmopressin.
  126. Robert Martin Gale, Methods for transdermal drug administration.
  127. Ganatra, Amit; Felix, Fabio; Shah, Bhavin; Bernasconi, Matthew; Rizk, Said; Martin, David P.; Williams, Simon F., Methods of orienting multifilament yarn and monofilaments of poly-4-hydroxybutyrate and copolymers thereof.
  128. Ganatra, Amit; Felix, Fabio; Shah, Bhavin; Bernasconi, Matthew; Rizk, Said; Martin, David P.; Williams, Simon F., Methods of orienting multifilament yarn and monofilaments of poly-4-hydroxybutyrate and copolymers thereof.
  129. Guido, Debora; Huang, Haiyong Hugh, Methods of preparing tamper resistant pharmaceutical formulations.
  130. Sackler, Richard S., Methods of preparing tamper resistant solid oral dosage forms.
  131. Reder Robert F. ; Goldenheim Paul D. ; Kaiko Robert F., Methods of providing sustained treatment with opioids.
  132. Nilsson, Anders; Lindner, Hans; Wittendorff, Jørgen, Methods of treatment using orodispersible desmopressin pharmaceutical formulations.
  133. Nilsson, Anders; Lindner, Hans; Wittendorff, Jçrgen, Methods using desmopressin acetate in orodispersible form.
  134. Berner Bret ; Ebert Charles ; Mazzenga Gerard C. ; Otte John H., Mixed solvent mutually enhanced transdermal therapeutic system.
  135. Bozik, Michael E.; Petzinger, Jr., Thomas; Gribkoff, Valentin, Modified release formulations of (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine and methods of using the same.
  136. Lee Eun Soo ; Watanabe Tyler ; Gale Robert M. ; Burkoth Terry L., Monoglyceride/lactate ester permeation enhancer for oxybutnin.
  137. Lee Eun Soo ; Watanabe Tyler ; Gale Robert M. ; Burkoth Terry L., Monoglyceride/lactate ester permeation enhancer for oxybutynin.
  138. Nuwayser,Elie S., Multi-layered microcapsules and method of preparing same.
  139. Andriola Robert (Putnam Valley NY) Moore Donald J. (Pomona NY) Asche Henning (Bettingen CHX), Multicompartmentalized transdermal patches.
  140. Jansen, Rolf R.; Coronado, Dina J., Multilayer drug delivery system with barrier against reservoir material flow.
  141. Ross, Russell Frederick, Nanopatterned medical device with enhanced cellular interaction.
  142. Stanley Theodore H. ; Hague Brian, Non-dissolvable drug-containing dosage-forms for use in the transmucosal delivery of a drug to a patient.
  143. Silverberg, Eric; Chandran, Rama; Foreman, Paul; Philbin, Michael; Shah, Smita, Non-reactive adhesive useful in transdermal drug delivery system.
  144. Litmanovitz,Dana; Laidlaw,Barbara J. F., Opioid formulations.
  145. Nilsson, Anders; Lindner, Hans; Wittendorff, Jørgen, Orodispersible dosage forms of desmopressin acetate.
  146. Ihara, Katsumi; Nagata, Mitsuhiro; Inazuki, Sayoko, Patch containing fentanyl for mucous membrane of oral cavity.
  147. Patel Dinesh C. (Murray UT) Chang Yunik (Lakewood NJ), Penetration enhancement with binary system of oleic acid, oleins, and oleyl alcohol with lower alcohols.
  148. Lee Eun Soo ; Yum Su II, Permeation enhances for transdermal drug delivery compositions, devices and methods.
  149. Liang, Alfred; Matthews, Frank; Boehm, Garth; Tang, Lijuan; Johnson, Frank; Stauffer, Joseph, Pharmaceutical composition.
  150. Matthews, Frank; Boehm, Garth; Tang, Lijuan; Liang, Alfred, Pharmaceutical composition.
  151. Wright, Curtis; Oshlack, Benjamin; Breder, Christopher, Pharmaceutical composition containing gelling agent.
  152. Bosse, Paul, Pharmaceutical compositions.
  153. Bosse, Paul, Pharmaceutical compositions.
  154. Bosse, Paul, Pharmaceutical compositions.
  155. Bosse, Paul, Pharmaceutical compositions.
  156. Bosse, Paul, Pharmaceutical compositions.
  157. Bosse, Paul; Ameling, John; Schachtel, Bernard; Takigiku, Ray, Pharmaceutical compositions.
  158. Bosse, Paul; Ameling, John; Schachtel, Bernard; Takigiku, Ray, Pharmaceutical compositions.
  159. Bosse, Paul; Ameling, John; Schachtel, Bernard; Takigiku, Ray, Pharmaceutical compositions.
  160. Bosse, Paul; Ameling, John; Schachtel, Bernard; Takigiku, Ray, Pharmaceutical compositions.
  161. Bosse, Paul; Ameling, John; Schachtel, Bernard; Takigiku, Ray, Pharmaceutical compositions.
  162. Bosse, Paul; Ameling, John; Schachtel, Bernard; Takigiku, Ray, Pharmaceutical compositions.
  163. Bosse, Paul; Ameling, John; Schachtel, Bernard; Takigiku, Ray, Pharmaceutical compositions.
  164. Bosse, Paul; Ameling, John; Schachtel, Bernard; Takigiku, Ray, Pharmaceutical compositions.
  165. Bosse, Paul; Ameling, John; Schachtel, Bernard; Takigiku, Ray, Pharmaceutical compositions.
  166. Matthews, Frank; Boehm, Garth; Tang, Lijuan; Liang, Alfred, Pharmaceutical compositions.
  167. Bosse, Paul; Ameling, John; Kozarek, William; Schachtel, Bernard; Higgins, John, Pharmaceutical compositions comprising 5HT receptor agonist and antiemetic particulates.
  168. Matthews, Frank; Boehm, Garth; Tang, Lijuan; Liang, Alfred, Pharmaceutical compositions for the deterrence and/or prevention of abuse.
  169. Bosse, Paul; Ameling, John; Schachtel, Bernard; Takigiku, Ray, Pharmaceutical compositions for treating or preventing pain.
  170. Bosse, Paul; Ameling, John; Schachtel, Bernard; Takigiku, Ray, Pharmaceutical compositions for treating or preventing pain.
  171. Bosse, Paul; Ameling, John; Schachtel, Bernard; Takigiku, Ray, Pharmaceutical compositions for treating or preventing pain.
  172. Bosse, Paul; Ameling, John; Schachtel, Bernard; Takigiku, Ray, Pharmaceutical compositions for treating or preventing pain.
  173. Fein, Seymour, Pharmaceutical compositions including low dosages of desmopressin.
  174. Fein, Seymour, Pharmaceutical compositions including low dosages of desmopressin.
  175. Fein, Seymour H., Pharmaceutical compositions including low dosages of desmopressin.
  176. Fein,Seymour H., Pharmaceutical compositions including low dosages of desmopressin.
  177. Wright, Curtis; Oshlack, Benjamin; Breder, Christopher, Pharmaceutical formulation containing gelling agent.
  178. Wright, Curtis; Oshlack, Benjamin; Breder, Christopher, Pharmaceutical formulation containing gelling agent.
  179. Wright, Curtis; Oshlack, Benjamin; Breder, Christopher, Pharmaceutical formulation containing gelling agent.
  180. Wright, Curtis; Oshlack, Benjamin; Breder, Christopher, Pharmaceutical formulation containing gelling agent.
  181. Wright, Curtis; Oshlack, Benjamin; Breder, Christopher, Pharmaceutical formulation containing gelling agent.
  182. Wright, Curtis; Oshlack, Benjamin; Breder, Christopher, Pharmaceutical formulation containing gelling agent.
  183. Wright, Curtis; Oshlack, Benjamin; Breder, Christopher, Pharmaceutical formulation containing gelling agent.
  184. Wright, Curtis; Oshlack, Benjamin; Breder, Christopher, Pharmaceutical formulation containing gelling agent.
  185. Wright, Curtis; Oshlack, Benjamin; Breder, Christopher, Pharmaceutical formulation containing gelling agent.
  186. Wright, Curtis; Oshlack, Benjamin; Breder, Christopher, Pharmaceutical formulation containing gelling agent.
  187. Wright, Curtis; Oshlack, Benjamin; Breder, Christopher, Pharmaceutical formulation containing gelling agent.
  188. Wright, Curtis; Oshlack, Benjamin; Breder, Christopher, Pharmaceutical formulation containing gelling agent.
  189. Wright, Curtis; Oshlack, Benjamin; Breder, Christopher, Pharmaceutical formulation containing gelling agent.
  190. Wright, Curtis; Oshlack, Benjamin; Breder, Christopher, Pharmaceutical formulation containing gelling agent.
  191. Wright, Curtis; Oshlack, Benjamin; Breder, Christopher, Pharmaceutical formulation containing gelling agent.
  192. Wright, Curtis; Oshlack, Benjamin; Breder, Christopher, Pharmaceutical formulation containing gelling agent.
  193. Wright, Curtis; Oshlack, Benjamin; Breder, Christopher, Pharmaceutical formulation containing gelling agent.
  194. Wright, Curtis; Oshlack, Benjamin; Breder, Christopher, Pharmaceutical formulation containing gelling agent.
  195. Wright, Curtis; Oshlack, Benjamin; Breder, Christopher, Pharmaceutical formulation containing gelling agent.
  196. Wright, Curtis; Oshlack, Benjamin; Breder, Christopher, Pharmaceutical formulation containing gelling agent.
  197. Wright, Curtis; Oshlack, Benjamin; Breder, Christopher, Pharmaceutical formulation containing gelling agent.
  198. Wright, Curtis; Oshlack, Benjamin; Breder, Christopher, Pharmaceutical formulation containing gelling agent.
  199. Wright, Curtis; Oshlack, Benjamin; Breder, Christopher, Pharmaceutical formulation containing gelling agent.
  200. Wright, Curtis; Oshlack, Benjamin; Breder, Christopher, Pharmaceutical formulation containing gelling agent.
  201. Wright, Curtis; Oshlack, Benjamin; Breder, Christopher, Pharmaceutical formulation containing gelling agent.
  202. Wright, Curtis; Oshlack, Benjamin; Breder, Christopher, Pharmaceutical formulation containing gelling agent.
  203. Wright, Curtis; Oshlack, Benjamin; Breder, Christopher, Pharmaceutical formulation containing gelling agent.
  204. Wright, Curtis; Oshlack, Benjamin; Breder, Christopher, Pharmaceutical formulation containing gelling agent.
  205. Wright, Curtis; Oshlack, Benjamin; Breder, Christopher, Pharmaceutical formulation containing gelling agent.
  206. Wright, Curtis; Oshlack, Benjamin; Breder, Christopher, Pharmaceutical formulation containing gelling agent.
  207. Wright, Curtis; Oshlack, Benjamin; Breder, Christopher, Pharmaceutical formulation containing gelling agent.
  208. Wright, Curtis; Oshlack, Benjamin; Breder, Christopher, Pharmaceutical formulation containing gelling agent.
  209. Wright, Curtis; Oshlack, Benjamin; Breder, Christopher, Pharmaceutical formulation containing gelling agent.
  210. Nilsson, Anders; Lindner, Hans; Wittendorff, Jørgen, Pharmaceutical formulations of desmopressin.
  211. Nilsson, Anders; Lindner, Hans; Wittendorff, Jørgen, Pharmaceutical formulations of desmopressin.
  212. Martin, David P.; Rizk, Said; Ahuja, Ajay; Williams, Simon F., Polyhydroxyalkanoate medical textiles and fibers.
  213. Martin, David P.; Rizk, Said; Ahuja, Ajay; Williams, Simon F., Polyhydroxyalkanoate medical textiles and fibers.
  214. Martin, David P.; Rizk, Said; Ahuja, Ajay; Williams, Simon F., Polyhydroxyalkanoate medical textiles and fibers.
  215. Martin, David P.; Rizk, Said; Ahuja, Ajay; Williams, Simon F., Polyhydroxyalkanoate medical textiles and fibers.
  216. Miranda Jesus (Menlo Park CA) Cleary Gary W. (San Mateo CA), Printed transdermal drug delivery device.
  217. Martin, David P.; Rizk, Said; Ahuja, Ajay; Williams, Simon F., Process of making polyhydroxyalkanoate medical textiles.
  218. Lothar W. Kleiner ; Robert M. Gale ; Randall G. Berggren ; Gilbert T. Tong ; Guohua Chen ; Keith E. Dionne ; Paul R. Houston, Rate controlling membranes for controlled drug delivery devices.
  219. Cormier Michel J. N. ; Daddona Peter E. ; Johnson Juanita A., Reduction of skin reactions caused by transdermal drug delivery.
  220. Cleary Gary W. (San Mateo CA) Roy Samir (Redwood City CA), Resilient transdermal drug delivery device.
  221. Qi, Xiaoyang, Saposin C-DOPS: a novel anti-tumor agent.
  222. Qi, Xiaoyang, Saposin C-DOPS: a novel anti-tumor agent.
  223. Lattin Gary A. ; Belden Tighe M. ; Withell Andrew J.,NZX, Self-contained transdermal drug delivery device.
  224. White, Bradley E.; Lemke, John; Hayter, Paul; Chen, Corinna X.; Read, Brian W.; Dougherty, Jason E., Self-test for analgesic product.
  225. White, Bradley E.; Lemke, John; Hayter, Paul; Chen, Corinna X.; Read, Brian W.; Dougherty, Jason E., Self-test for analgesic product.
  226. White, Bradley E.; Lemke, John; Hayter, Paul; Chen, Corinna X.; Read, Brian W.; Dougherty, Jason E., Self-test for analgesic product.
  227. Boehm, Garth, Sequestering subunit and related compositions and methods.
  228. Boehm, Garth, Sequestering subunit and related compositions and methods.
  229. Beste Russell D. ; Hamlin Richard D., Skin permeation enhancer compositions comprising a monoglyceride and ethyl palmitate.
  230. Taskovich Lina T. (Palo Alto CA), Skin permeation enhancer compositions using glycerol monooleate.
  231. Osborne James L. (Mountain View CA) Nelson Melinda (Sunnyvale CA) Enscore David J. (Saratoga CA) Yum Su I. (Los Altos CA) Gale Robert M. (Los Altos CA), Subsaturated nicotine transdermal therapeutic system.
  232. Osborne James L. ; Nelson Melinda ; Enscore David J. ; Yum Su Il ; Gale Robert M., Subsaturated nicotine transdermal therapeutic system.
  233. Enscore David J. (Sunnyvale CA) Campbell Patricia S. (Palo Alto CA) Osborne James L. (Mountain View CA) Smart Melinda K. (Sunnyvale CA) Yum Su I. (Los Altos CA), Subsaturated transdermal therapeutic system having improved release characteristics.
  234. Molitor, Nicholas G.; Vitali, Dario; Koch, Jr., Robert L.; Huitema, Thomas W.; Larson, Kevin A.; Fuchs, Richard P., Surgical clip advancement mechanism.
  235. Vitali, Dario; Molitor, Nicholas G.; Huitema, Thomas W.; Koch, Jr., Robert L.; Bertke, Brian D.; Larson, Kevin A.; Fuchs, Robert P.; Davison, Mark A., Surgical clip applier methods.
  236. Vitali, Dario; Molitor, Nicholas G.; Huitema, Thomas W.; Koch, Jr., Robert L.; Bertke, Brian D.; Larson, Kevin A.; Fuchs, Robert P.; Davison, Mark A., Surgical clip applier methods.
  237. Vitali, Dario; Molitor, Nicholas G.; Huitema, Thomas W.; Koch, Robert L.; Bertke, Brian D.; Larson, Kevin A.; Fuchs, Robert P.; Davison, Mark A., Surgical clip applier methods.
  238. Huitema, Thomas W.; Koch, Jr., Robert L., Surgical clip applier ratchet mechanism.
  239. Huitema, Thomas W.; Koch, Jr., Robert L., Surgical clip applier ratchet mechanism.
  240. Lemke, John; Satre, Scot; Chen, Corinna X.; Read, Brian W., Switch validation circuit and method.
  241. Lemke, John; Satre, Scot; Chen, Corinna X.; Read, Brian W.; Dougherty, Jason E.; Joshi, Nitin B., Switch validation circuit and method.
  242. Chen, Weirong; Humora, Michael; Kwok, Daw-Iong Albert; Kiesman, William F.; Irdam, Erwin Ayandra, Synthesis of amine substituted 4,5,6,7-tetrahydrobenzothiazole compounds.
  243. Chen, Weirong; Humora, Michael; Kwok, Daw-long Albert; Kiesman, William F.; Irdam, Erwin Ayandra, Synthesis of amine substituted 4,5,6,7-tetrahydrobenzothiazole compounds.
  244. Raje, Prasad; Gadikota, Rajendrakumar Reddy; Chen, Jian-Xie; Lapina, Olga V.; McCall, John M., Synthesis of chirally purified substituted benzothiazole diamines.
  245. Raje, Prasad; Gadikota, Rajendrakumar Reddy; Chen, Jian-Xie; Lapina, Olga V.; McCall, John M., Synthesis of chirally purified substituted benzothiazole diamines.
  246. Judd Amrit K. (Belmont CA) Bucher Doris J. (New York NY) Popple Steven W. (Brooklyn NY), Synthetic peptides for diagnosis and prevention of influenza virus infection and their use.
  247. Hummel, Michele; Kyle, Donald J.; Whiteside, Garth, Systems and methods for treating an opioid-induced adverse pharmacodynamic response.
  248. Hummel, Michele; Kyle, Donald J.; Whiteside, Garth, Systems and methods for treating an opioid-induced adverse pharmacodynamic response.
  249. Hummel, Michele; Kyle, Donald J.; Whiteside, Garth, Systems and methods for treating an opioid-induced adverse pharmacodynamic response.
  250. Hummel, Michele; Kyle, Donald J.; Whiteside, Garth, Systems and methods for treating an opioid-induced adverse pharmacodynamic response.
  251. Hummel, Michele; Kyle, Donald J.; Whiteside, Garth, Systems and methods for treating an opioid-induced adverse pharmacodynamic response.
  252. Hummel, Michele; Kyle, Donald J.; Whiteside, Garth, Systems and methods for treating an opioid-induced adverse pharmacodynamic response.
  253. Hummel, Michelle; Kyle, Donald J.; Whiteside, Garth, Systems and methods for treating an opioid-induced adverse pharmacodynamic response.
  254. Hummel, Michele; Kyle, Donald J.; Whiteside, Garth, Systems for treating an opioid-induced adverse pharmacodynamic response.
  255. Huang, Haiyong Hugh, Tamper resistant controlled release dosage forms.
  256. Huang, Haiyong Hugh, Tamper resistant controlled release dosage forms.
  257. Guido, Debora; Huang, Haiyong Hugh, Tamper resistant pharmaceutical formulations.
  258. Guido, Debora; Huang, Haiyong Hugh, Tamper resistant pharmaceutical formulations.
  259. Guido, Debora; Huang, Haiyong Hugh, Tamper resistant pharmaceutical formulations.
  260. Guido, Debora; Huang, Haiyong Hugh, Tamper resistant pharmaceutical formulations.
  261. Shmeis, Rama Abu; Muley, Sheetal R.; Shen, Xiaohong; Zong, Zhixin, Tamper resistant pharmaceutical formulations.
  262. Shmeis, Rama Abu; Muley, Sheetal R.; Shen, Xiaohong; Zong, Zhixin, Tamper resistant pharmaceutical formulations.
  263. Sackler, Richard S., Tamper resistant solid oral dosage forms.
  264. Howard, Stephen A.; Reidenberg, Bruce, Tamper resistant transdermal dosage form.
  265. Howard, Stephen A.; Reidenberg, Bruce, Tamper resistant transdermal dosage form.
  266. Aung-Din, Ronald, Topical regional neuro-affective therapy.
  267. Aung-Din, Ronald, Topical regional neuro-affective therapy in mammals with cannabinoids.
  268. Aung-Din, Ronald, Topical therapy for migraine.
  269. Aung-Din, Ronald, Topical therapy for migraine.
  270. Aung-Din, Ronald, Topical therapy for the treatment of migraines, muscle sprains, muscle spasms, spasticity and related conditions.
  271. Kurihara-Bergstrom Tamie (New City NY) Good William R. (Suffern NY) Ebert Charles D. (Salt Lake City UT), Transdermal administration of a systemic active agent to a premature neonatal infant.
  272. Gale, Robert M.; Stein, Thomas M.; Audett, Jay; Stepic, Jane; Phipps, Joseph B.; Cormier, Michael J. N., Transdermal analgesic systems with reduced abuse potential.
  273. Gale, Robert M.; Stein, Thomas M.; Audett, Jay; Stepic, Jane; Phipps, Joseph B.; Cormier, Michel J. N., Transdermal analgesic systems with reduced abuse potential.
  274. Shipman ; Jr. Charles (Dexter MI) Nassiri Mohammad R. (Ann Arbor MI) Flynn Gordon L. (Ann Arbor MI), Transdermal delivery of the narcotic analgesics etorphine and analogs.
  275. Schacht, Dietrich Wilhelm; Hannay, Mike; Wolff, Hans-Michael, Transdermal delivery system.
  276. Yum, Su Il; Theeuwes, Felix, Transdermal delivery system for sufentanil.
  277. Yum, Su Il; Theeuwes, Felix, Transdermal delivery system for sufentanil.
  278. Schacht, Dietrich Wilhelm; Hannay, Mike; Wolff, Hans-Michael, Transdermal delivery system for the administration of rotigotine.
  279. Schacht, Dietrich Wilhelm; Hannay, Mike; Wolff, Hans-Michael, Transdermal delivery system for the administration of rotigotine.
  280. Yum, Su II; Kwon, Sung Yun; Song, Xiaoping; Brown, James E., Transdermal delivery systems.
  281. Yum, Su Il; Kwon, Sung Yun; Song, Xiaoping; Brown, James E., Transdermal delivery systems.
  282. Yum, Su Il; Theeuwes, Felix, Transdermal delivery systems.
  283. Lee,Eun Soo; Yum,Su Il, Transdermal drug delivery device.
  284. Watanabe, Tyler; Gale, Robert M., Transdermal drug delivery device package with improved drug stability.
  285. Woodard John T. (Midland MI) Metevia Virgil L. (Saginaw MI), Transdermal drug delivery devices with amine-resistant silicone adhesives.
  286. Tang, Jiansheng, Transdermal drug delivery systems comprising a coated release liner.
  287. Chang Yunik (Toms River NJ), Transdermal drug delivery using a dual permeation enhancer and method of performing the same.
  288. Cleary Gary W. (San Mateo CA) Roy Samir (Redwood City CA), Transdermal drug-delivery composition.
  289. Gale, Robert M.; Audett, Jay; Padmanabhan, Rama V.; Cormier, Michel J. N.; Luciano, Allison; Silverberg, Eric N.; Foreman, Paul B., Transdermal nicotine salt delivery system.
  290. Gale, Robert M.; Audett, Jay; Padmanabhan, Rama V.; Cormier, Michel J. N.; Luciano, Allison; Silverberg, Eric N.; Foreman, Paul B., Transdermal nicotine salt delivery system.
  291. Ross, Russell F., Transdermal patch containing microneedles.
  292. Fowler, William V.; Anderson, Carter R., Transdermal patch disposal system.
  293. Fowler, William; Anderson, Carter, Transdermal patch disposal system.
  294. Ito, Takeshi; Tateishi, Tetsuro; Higo, Naruhito, Transdermal patch for external use comprising fentanyl.
  295. Miller, II, Kenneth J., Transdermal patch incorporating active agent migration barrier layer.
  296. Miller, II, Kenneth J., Transdermal patch incorporating active agent migration barrier layer.
  297. Miller, II, Kenneth J., Transdermal patch incorporating active agent migration barrier layer.
  298. Amano, Satoshi; Shinoda, Tomohiro; Kase, Natsumi; Mori, Keita, Transdermal preparation.
  299. Woeller, Karl-Heinz; Kolbe, Ludger; Scherner, Cathrin; Wolber, Rainer, Transdermal therapeutic patches containing 4-N-butylresorcinol.
  300. M��ller,Walter, Transdermal therapeutic system (TTS) with fentanyl as a active ingredient.
  301. Deshmukh, Abhijit Mukund; Dixit, Akhilesh; Kumar, Prasanna; Bindra, Vikram, Transdermal therapeutic system for extended dosing of pramipexole in treating neurological disorders.
  302. Gale, Robert M., Transparent transdermal nicotine delivery devices.
  303. Gale, Robert M., Transparent transdermal nicotine delivery devices.
  304. Gale, Robert M., Transparent transdermal nicotine delivery devices.
  305. Gale, Robert M., Transparent transdermal nicotine delivery devices.
  306. Gale, Robert M., Transparent transdermal nicotine delivery devices.
  307. Ebert, Charles D.; Sanders, Steven W., Unoccluded topical oxybutynin gel composition and methods for transdermal oxybutynin therapy.
  308. Bond, Richard A.; Glass, Mitchell, Use of beta-adrenergic inverse agonists for smoking cessation.
섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트

맨위로