초록 ▼

A dispensing device is disclosed for delivering a beneficial agent. The device comprises (1) a semipermeable housing defining an internal space, (2) a dense member in the space, (3) a heat responsive composition containing a beneficial agent in the space, (4) an expandable member in the space, and (

A dispensing device is disclosed for delivering a beneficial agent. The device comprises (1) a semipermeable housing defining an internal space, (2) a dense member in the space, (3) a heat responsive composition containing a beneficial agent in the space, (4) an expandable member in the space, and (5) a passageway in the semipermeable housing for delivering the beneficial agent from the dispensing device.

대표청구항 ▼

A delivery system for delivering a beneficial agent formulation to an environment of use, the delivery system comprising: (a) a wall that surrounds and defines an internal lumen, the wall comprising a semipermeable composition that is permeable to the passage of fluid and substantially impermeable t

A delivery system for delivering a beneficial agent formulation to an environment of use, the delivery system comprising: (a) a wall that surrounds and defines an internal lumen, the wall comprising a semipermeable composition that is permeable to the passage of fluid and substantially impermeable to the passage of a beneficial agent; (b) means in the lumen for maintaining the delivery system in the environment of use over time, said means having a density of at least 1.5; (c) means in the lumen for expanding and occupying an increased volume of the lumen; (d) a heat sensitive beneficial agent formulation in the lumen that forms a dispensable formulation at a temperature of at least 31°C.; and, (e) means in the delivery system for communicating with the lumen for delivering the beneficial agent to the environment of use over time.