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Biodegradable porous ceramic delivery system for bone morphogenetic protein 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61F-002/28
  • A61F-002/32
  • C07G-007/00
출원번호 US-0609810 (1984-05-14)
발명자 / 주소
  • Urist Marshall R. (Pacific Palisade CA)
출원인 / 주소
  • The Regents of the University of California (Berkeley CA 02)
인용정보 피인용 횟수 : 277  인용 특허 : 8

초록

Disclosed is a biodegradable porous ceramic delivery system useful for delivery of bone morphogenic protein (BMP) to viable tissue and to induce formation of new bone therein. The delivery composite is substantially pure BMP in combination with a biodegradable porous ceramic (sintered), e.g. beta-tr

대표청구항

A composition comprising a physiologically acceptable, biodegradable porous ceramic containing bone morphogenic protein (BMP).

이 특허에 인용된 특허 (8)

  1. Broemer Heinz (Hermannstein DT) Kaes Hans-Herbert (Wetzlar-Dorlar DT) Pfeil Emanuel (Marburg DT), Biocompatible glass ceramic material.
  2. Urist Marshall R. (Pacific Palisades CA), Bone morphogenetic protein.
  3. Urist Marshall R. (Pacific Palisade CA), Bone morphogenetic protein process.
  4. Reiner Roland (Eishborn DEX) KiBing Wolfgang (Eschwege DEX) Dring Helga (Cologne DEX) Kster-Lsche Kari (Usingen DEX) Heide Helmut (Kelkheim DEX), Implantable drug depot and process for the production thereof.
  5. Wahlig Helmut (Darmstadt DEX) Dingeldain Elvira (Dreieich DEX) Braun Dietrich (Darmstadt-Arheilgen DEX), Medicinally useful, shaped mass of collagen resorbable in the body.
  6. Jefferies Steven R. (5802 Leith Walk Baltimore MD 21239), Method of inducing osseous formation by implanting bone graft material.
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  8. Simon Jaime (Angleton TX) Wilson David A. (Richwood TX) Volkert Wynn A. (Columbia MO), Radioactive metals complexed with phosphonate derivatives of bicycloheptane bis(alkylamines).

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