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Permanently bonded antithrombogenic polyurethane surface 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A01N-001/02
  • B05D-003/04
  • B05D-003/10
출원번호 US-0841505 (1986-03-19)
발명자 / 주소
  • Solomon Donald D. (Spring Valley OH) McGary Charles W. (Centerville OH) Pascarella Vincent J. (Dayton OH)
출원인 / 주소
  • Becton, Dickinson and Company (Franklin Lakes NJ 02)
인용정보 피인용 횟수 : 56  인용 특허 : 2

초록

An antithrombogenic polyurethane polymer being bound to a support substrate wherein the antithrombogenic agent is reacted through an aldehyde group with an amine functionality of a polyurethane-urea to form the covalently bonded antithrombogenic material.

대표청구항

A process for imparting antithrombogenic activity to polyurethane polymer materials, which comprises: a. treating the surface of a solid support with a solution of a protonated amine rich polyurethane-urea so that the polyurethane-urea is bonded to the support substrate; b. removing solvent from the

이 특허에 인용된 특허 (2)

  1. Kira Kazuaki (Kobe JPX), Antithrombogenic elastomer, molded products of the same, and a process for manufacturing the same.
  2. Solomon Donald D. (Spring Valley OH) McGary Charles W. (Centerville OH) Pascarella Vincent J. (Dayton OH), Covalent bonded antithrombogenic polyurethane material.

이 특허를 인용한 특허 (56)

  1. Calvo, Eric; Marinotti, Osvaldo; Ribeiro, Jose M. C.; Francischetti, Ivo M., Aegyptin and uses thereof.
  2. Calvo, Eric; Marinotti, Osvaldo; Ribeiro, Jose M. C.; Francischetti, Ivo M., Aegyptin and uses thereof.
  3. Calvo, Eric; Marinotti, Osvaldo; Ribeiro, Jose M. C.; Francischetti, Ivo M., Aegyptin and uses thereof.
  4. Solomon Donald D. ; Byron M. Parke, Anti-infective and antithrombogenic medical articles and method for their preparation.
  5. Joseph A. Chinn ; R. Michael Casanova, Antimicrobial annuloplasty ring having a biodegradable insert.
  6. Joseph A. Chinn ; R. Michael Casanova, Antithrombogenic annuloplasty ring having a biodegradable insert.
  7. Larsson Kare V. (Bjrred) Bergentz Sven E. (Malm) Lindblad Bengt L. T. (Malm SEX), Antithrombogenic article containing lysozyme and heparin adsorbed on a substrate.
  8. Cahalan Linda L. (Geleen NLX) Cahalan Patrick T. (Geleen NLX) Verhoeven Michel (Maastricht NLX) Hendriks Marc (Hoensbroek NLX) Fouache Benedicte (Maastricht NLX), Biocompatible medical article and method.
  9. Cahalan Linda L.,NLX ; Cahalan Patrick T.,NLX ; Verhoeven Michel,NLX ; Hendriks Marc,NLX ; Fouache Benedicte,NLX, Biocompatible medical article and method.
  10. Schwartz Robert S. (Rochester MN) Wolff Rodney G. (Minnetonka Beach MN), Bioelastomeric stent.
  11. Schwartz Robert S. (Rochester MN) Wolff Rodney G. (Minnetonka Beach MN), Bioelastomeric stent.
  12. Tuch Ronald J., Blood contacting medical device and method.
  13. Tuch Ronald J., Blood-contacting medical device and method.
  14. Patnaik Birendra K., Bonding bio-active materials to expanded polytetrafluoroethylene or polyethylene terephthalate via an isocyanate-terminated spacer.
  15. Patnaik Birendra K., Bonding bio-active materials to substrate surfaces.
  16. Patnaik, Birendra K.; Zdrahala, Richard J., Composition and process for preparing biocompatible polymer coatings.
  17. Alferiev, Ivan; Fishbein, Ilia; Levy, Robert J., Derivatized polyurethane compositions which exhibit enhanced stability in biological systems and methods of making the same.
  18. Levy Robert J. ; Alferiev Ivan, Derivatized polyurethane compositions which exhibit enhanced stability in biological systems and methods of making the same.
  19. Levy, Robert J.; Alferiev, Ivan, Derivatized polyurethane compositions which exhibit enhanced stability in biological systems and methods of making the same.
  20. Dinh Thomas Q. (Minnetonka MN) Tuch Ronald J. (Plymouth MN) Schwartz Robert S. (Rochester MN), Drug eluting stent.
  21. Dinh Thomas Q. (Minnetonka MN) Tuch Ronald J. (Plymouth MN) Schwartz Robert S. (Rochester MN), Drug eluting stent.
  22. Koulik, Edouard, Heparin compositions and methods of making and using the same.
  23. Koulik, Edouard, Heparin compositions and methods of making and using the same.
  24. Keogh James R., Ionic attachment of biomolecules with a guanidino moiety to medical device surfaces.
  25. Fan You Ling ; Marlin Lawrence ; Bouldin Lisa M. ; Marino Isabel Maria, Lubricious coatings containing polymers with vinyl and carboxylic acid moieties.
  26. Keogh James R., Method for covalent attachment of biomolecules to surfaces of medical devices.
  27. Patnaik, Birendra K.; Lin, Horng-Ban; Lentz, David J.; Zdrahala, Richard J., Method for imparting a bio-active coating.
  28. Verhoeven Michel (Maastricht NLX) Cahalan Linda L. (Geleen NLX) Hendriks Marc (Hoensbroek NLX) Fouache Benedicte (Hoensbroek NLX) Cahalan Patrick T. (Geleen NLX), Method for making heparinized biomaterials.
  29. Dinh Thomas Q. (Minnetonka MN) Dror Michael (Edina MN) Schwartz Robert S. (Rochester MN), Method for preventing restenosis.
  30. Chinn, Joseph A.; Phillips, Jr., Richard E.; Sauter, Joseph A.; Casanova, R. Michael; Pathak, Chandrashekhar P.; Moore, Mark A.; Bruce, L. Diane, Method for producing antimicrobial antithrombogenic medical devices.
  31. Yudelson Joseph S. (Rochester NY) Verdone Joseph A. (Rochester NY), Method of hardening.
  32. Dinh Thomas Q. (Minnetonka MN) Tuch Ronald J. (Plymouth MN) Schwartz Robert S. (Rochester MN), Method of making a drug eluting stent.
  33. Michal, Eugene T.; Ding, Ni; Buchko, Christopher, Methods for immobilizing anti-thrombogenic material onto a medical device or into a coating thereon.
  34. Bezuidenhout, Deon; Theron, Jacobus P.; Higham, Lawrence J.; Zilla, Peter P., Modification of thermoplastic polymers.
  35. Fan You L. (East Brunswick NJ) Marlin Lawrence (Bridgewater NJ) Bouldin Lisa M. (Cranford NJ) Marino Isabel M. (Somerset NJ), Non-reactive lubicious coating process.
  36. Keogh James R., Oxidative method for attachment of biomolecules to surfaces of medical devices.
  37. Keogh James R., Oxidative method for attachment of glycoproteins or glycopeptides to surfaces of medical devices.
  38. Keogh James R., Oxidative method for attachment of glycoproteins to surfaces of medical devices.
  39. Keogh James R., Periodate oxidative method for attachment and crosslinking of biomolecules to medical device surfaces.
  40. Keogh James R., Periodate oxidative method for attachment of biomolecules to medical device surfaces.
  41. Birendra K. Patnaik ; Richard J. Zdrahala, Polymer coatings grafted with polyethylene oxide chains containing covalently bonded bio-active agents.
  42. Patnaik Birendra K. ; Zdrahala Richard J., Polymer coatings grafted with polyethylene oxide chains containing covalently bonded bio-active agents.
  43. Patnaik Birendra K. ; Zdrahala Richard J., Polyurethanes grafted with polyethylene oxide chains containing covalently bonded heparin.
  44. Wirt David F. ; Sirvio Larry M., Process for modifying surfaces using the reaction product of a water-insoluble polymer and a polyalkylene imine.
  45. Hostettler Fritz ; Rhum David ; Forman Michael R. ; Helmus Michael N. ; Ding Ni, Process for preparation of slippery, tenaciously adhering, hydrophilic polyurethane hydrogel coating, coated polymer and metal substrate materials, and coated medical devices.
  46. Patnaik Birendra K. ; Zdrahala Richard J., Process for preparing polymer coatings grafted with polyethylene oxide chains containing covalently bonded bio-active a.
  47. Hostettler Fritz (Lambertville NJ) Rhum David (New York NY) Forman Michael R. (Ramsey CA) Helmus Michael N. (St. Louis Park MN) Ding Ni (Plymouth MN), Process for producing slippery, tenaciously adhering hydrogel coatings containing a polyurethane-urea polymer hydrogel c.
  48. Hostettler Fritz ; Rhum David ; Forman Michael R. ; Helmus Michael N. ; Ding Ni, Process for the preparation of slippery, tenaciously adhering, hydrophilic polyurethane hydrogel coatings, coated metal substrate materials, and coated medical devices.
  49. Hostettler Fritz ; Rhum David ; Forman Michael R. ; Helmus Michael N. ; Ding Ni, Process for the preparation of slippery, tenaciously adhering, hydrophilic polyurethane hydrogel coatings, coated polymer and metal substrate materials, and coated medical devices.
  50. Wirt David F. ; Sirvio Lary M., Removal of biologically active agents.
  51. Hostettler Fritz ; Rhum David ; Forman Michael R. ; Helmus Michael N. ; Ding Ni, Slippery, tenaciously adhering hydrophilic polyurethane hydrogel coatings, coated metal substrate materials, and coated medical devices.
  52. Hostettler Fritz ; Rhum David ; Forman Michael R. ; Helmus Michael N. ; Ding Ni, Slippery, tenaciously adhering hydrophilic polyurethane hydrogel coatings, coated polymer substrate materials, and coated medical devices.
  53. Levy, Robert J.; Alferiev, Ivan; Stachelek, Stanley J., Steroid lipid-modified polyurethane as an implantable biomaterial, the preparation and uses thereof.
  54. Levy, Robert J.; Alferiev, Ivan; Stachelek, Stanley J., Steroid lipid-modified polyurethane as an implantable biomaterial, the preparation and uses thereof.
  55. Levy,Robert J.; Alferiev,Ivan; Stachelek,Stanley J., Steroid lipid-modified polyurethane as an implantable biomaterial, the preparation and uses thereof.
  56. Patnaik Birendra K. ; Lin Horng-Ban ; Lentz David J. ; Zdrahala Richard J., ePTFE small caliber vascular grafts with significant patency enhancement via a surface coating which contains covalently bonded heparin.
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