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A process for coating a polymer surface with a hydrophilic coating with low friction in wet condition. The process comprises applying to the polymer surface a solution containing between 0.05 to 40% of a compound which comprises at least two unreacted isocyanate groups per molecule, evaporating the

A process for coating a polymer surface with a hydrophilic coating with low friction in wet condition. The process comprises applying to the polymer surface a solution containing between 0.05 to 40% of a compound which comprises at least two unreacted isocyanate groups per molecule, evaporating the solvent, applying a solution containing between 0.5 to 50% of polyvinylpyrrolidone to the thus treated polymer surface and then evaporating the solvent of the last mentioned solution, and curing the coating at elevated temperature. The process is preferably carried out in the presence of a catalyst for the curing of isocyanate.

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A medical article for insertion in the body which is provided with a hydrophilic coating prepared in accordance with a process which consists essentially of applying a solution to the surface of an article made from a polymer selected from the group consisting of rubber, vinyl polymers, polyesters a

A medical article for insertion in the body which is provided with a hydrophilic coating prepared in accordance with a process which consists essentially of applying a solution to the surface of an article made from a polymer selected from the group consisting of rubber, vinyl polymers, polyesters and polyacrylates, which solution consists essentially of an organic solvent and a solute in an amount of between 0.05 to 40% (weight to volume), said solute consisting essentially of an isocyanate monomer having at least 2 unreacted isocyanate groups per molecule, an isocyanate prepolymer thereof having up to 5 monomer units, or a mixture of such monomers and prepolymers, evaporating the solvent, applying a second solution consisting essentially of a solvent containing between 0.5 to 10% (weight to volume) of polyvinyl pyrrolidone to the thus treated polymer surface, and then evaporating the solvent of the second solution and curing the coating in the presence of a water-containing gas at elevated temperature. A medical article according to claim 5 wherein the isocyanate is selected from the group consisting of toluene diisocyanate, hexamethylene diisocyanate and 4,4′-diphenylmethane diisocyanate. A medical article according to claim 5 wherein the polymer surface to be coated comprises a polymer selected from the group consisting of latex rubber and polyvinylchloride. A medical article according to claim 6 wherein the hydrophilic coating is treated with iodine. A medical article according to claims 5, 6, 7 or 8 which comprises a catheter.