초록 ▼

A dosage inhalator for the inhalation of a pharmacologically active compound in solution form is disclosed. The inhalator comprises a propellant container, a propellant dispensing unit, and a dosing unit for dosing the pharmacologically active compound. The dosing unit comprises a storage chamber fo

A dosage inhalator for the inhalation of a pharmacologically active compound in solution form is disclosed. The inhalator comprises a propellant container, a propellant dispensing unit, and a dosing unit for dosing the pharmacologically active compound. The dosing unit comprises a storage chamber for the active compound, a dose loading unit directly connected thereto, and a nozzle. The does loading unit comprises a movable perforated membrane, and a holder for the perforated membrane. The membrane is displaceable between a first position where a solution of active compound is introduced into the perforations of the membrane, and second position where the perforations of the membrane are inserted into a propellant passage. While the membrane is in the second position, the propellant dispensing unit may be operated, allowing propellant originally stored in the propellant container to remove the solution of the active compound from the perforations inserted into the propellant passage and carry said solution out the nozzle.

대표청구항 ▼

An inhaler for administering a solution of a phramacologically active compound to a patient as droplets suspended in a propellant comprising: a gas conduit through which a dose of said solution suspended in said propellant is supplied to said patient, a storage chamber means for storing said solutio

An inhaler for administering a solution of a phramacologically active compound to a patient as droplets suspended in a propellant comprising: a gas conduit through which a dose of said solution suspended in said propellant is supplied to said patient, a storage chamber means for storing said solution, a perforated membrane having a plurality of preselected portions each adapted to hold and dispense a reproducible unit dose \less than 50 mg of said compound in solution, and a propellant supply unit for supplying a pharmacologically acceptable propellant to the inhaler, said conduit, membrane and propellant supply unit being operably connected to each other so that propellant released from the propellant supply unit passes through one of said preselected portions of said perforated membrane that is positioned across said gas conduit, releases said solution carried thereby, and carries said solution as suspended droplets through said gas conduit to the patient, wherein said perforated membrane is adapted to be displaceable through a plurality of positions in each of which another preselected portion thereof holding a reproducible dose of said solution is moved into a dispensing postion relative to said gas conduit and propellant supply unit, and another portion thereof is moved into said storage chamber, and whereby reproducible doses of the solution can be transferred from said storage chamber means by said membrane, positioned across said gas conduit by said membrane, and removed therefrom by propellant discharged from said propellant supply unit.