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Pharmaceutical products providing enhanced analgesia 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-031/19
  • A61K-031/16
출원번호 US-0684642 (1984-12-24)
발명자 / 주소
  • Brand Larry M. (West Chester OH)
출원인 / 주소
  • The Procter & Gamble Company (Cincinnati OH 02)
인용정보 피인용 횟수 : 39  인용 특허 : 15

초록

An analgesic composition comprising capsaicin or a capsaicin analogue and an analgesic selected from the class of non-steroidal anti-inflammatory, antipyretic and analgesic drugs is disclosed. This combination has been found to exhibit unexpectedly enhanced analgesic activity in humans and lower ani

대표청구항

An analgesic composition comprising a safe and effective amount of: (a) a capsaicinoid analgesic compound of the general formula: [Figure] wherein R1 is selected from the group consisting of OH and OCH3, X is selected from the group consisting of [Figure] and R is a C16-C21 cis-monounsaturated alken

이 특허에 인용된 특허 (15)

  1. Capetola Robert J. (Doylestown PA) McGuire John L. (Whitehouse Station NJ), Analgesic composition.
  2. Capetola, Robert J.; McGuire, John L., Analgesic composition.
  3. Schmidt William K. (Wilmington DE), Analgesic mixture of nalbuphine and ibuprofen.
  4. Schmidt William K. (Wilmington DE), Analgesic mixture of nalbuphine and indomethacin.
  5. Schmidt William K. (Wilmington DE), Analgesic mixture of nalbuphine and zomepirac.
  6. Yamamoto ; Hisao ; Inukai ; Toshiya ; Koga ; Yoshihiko, Analgetic composition.
  7. LaHann Thomas R. (Cleves OH) Buckwalter Brian L. (Yardley PA), Hydroxyphenylacetamides having analgesic and anti-irritant activity.
  8. Flora Lawrence (Hamilton OH) Francis Marion D. (Cincinnati OH), Indole anti-inflammatory composition.
  9. Flora Lawrence (Hamilton OH) Francis Marion D. (Cincinnati OH), Isobutylphenylacetate anti-inflammatory composition.
  10. Nelson Edward B. (Williamsville NY), Method for analgesia using 3-hydroxyacetanilide.
  11. LaHann Thomas R. (Cleves OH), Method of producing analgesia.
  12. Buckwalter Brian L. (Yardley PA) LaHann Thomas R. (Cleves OH), Novel sulfonamide derivatives.
  13. Flora Lawrence (Hamilton OH) Francis Marion D. (Cincinnati OH), Phenylacetate anti-inflammatory composition.
  14. Flora Lawrence (Hamilton OH) Francis Marion D. (Cincinnati OH), Pyrazolidine anti-inflammatory composition and methods of use.
  15. Flora Lawrence (Hamilton OH) Francis Marion D. (Cincinnati OH), Salicylate anti-inflammatory composition.

이 특허를 인용한 특허 (39)

  1. Ohannesian Lena A. ; Nadig David ; Higgins ; III John D. ; Rey Max,SEX ; Martellucci Stephen A., Alkali metal and alkaline-earth metal salts of acetaminophen.
  2. Fossel, Eric T., Beneficial effects of increasing local blood flow.
  3. Fossel, Eric T., Delivery of ibuprofen and other compounds.
  4. Fossel, Eric T., Delivery of ibuprofen and other compounds.
  5. Fossel, Eric T., Delivery of ibuprofen and other compounds.
  6. Grassano Alessandro,ITX ; Marchiorri Maurizio,ITX ; Di Toro Mauro,ITX ; Castegini Franco,ITX, Fast dissolving compositions having analgesic activity.
  7. Loew Dieter (Wuppertal DEX) Schuster Otto (Frankfurt DEX) Lukas H. (Frankfurt DEX), Ibuprofen-containing medicament.
  8. Burch, Ronald; Carter, Richard B.; Lazar, Jeff, Infiltration of capsaicin into surgical sites and open wounds.
  9. Burch, Ronald; Carter, Richard B.; Lazar, Jeff, Injectable capsaicin.
  10. Sangameswaran, Lakshmi; Kramer, Susan, Instillation administration of capsaicinoids for the treatment of pain.
  11. Haas Ronald T. (West Windsor Township ; Mercer County NJ), Liquid ibuprofen compositions and methods of making them.
  12. Park Moo K. (Fayetteville NY) Caldwell Henry C. (Wilmington NC), Liquid oral pharmaceutical compositions of non-steroidal anti-inflammatory drugs.
  13. Park Moo K. (Rockville MD) Caldwell Henry C. (Ambler PA), Liquid oral pharmaceutical compositions of non-steroidal anti-inflammatory drugs.
  14. Bernstein Joel E. (Deerfield IL), Method and compositions utilizing capsaicin as an external analgesic.
  15. Holt Stephen D., Non-irritating capsaicin formulations and applicators therefor.
  16. Mody Dhiraj S. (Hammonton NJ) Mogavero Annabelle (Deptford NJ), Pediatric ibuprofen compositions.
  17. Yang Heechung ; Nguyen Vu Anh ; Dong Liang C. ; Wong Patrick S. L., Peptide formulation.
  18. Stroppolo Federico,CHX ; Bonadeo Daniele,ITX ; Pagano Alberto,ITX ; Gazzaniga ; deceased Annibale,ITX ITX by Cisella Adele Marabelli Gazzaniga ; Giovanni Battista Gazzaniga ; legal representatives ; , Solid pharmaceutical compositions containing (S)-2-(4-isobutylphenyl) propionic acid active ingredient and microcrystal.
  19. Ho Ying T. R. (Haddonfield NJ) Blank Robert G. (Vineland NJ), Spray dried ibuprofen.
  20. Reuter Gerald L. (Plattsburgh NY) Harrison Maureen M. (St. Albans VT), Spray dried ibuprofen.
  21. Reuter Gerald L. (Plattsburgh NY) Harrison Maureen M. (St. Albans VT), Spray dried ibuprofen.
  22. Bakthavatchalam,Rajagopal; Blum,Charles A.; Brielmann,Harry; Caldwell,Timothy M.; De Lombaert,Stephane; Hodgetts,Kevin J.; Zheng,Xiaozhang, Substituted quinazolin-4-ylamine analogues.
  23. Bakthavatchalam,Rajagopal; Blum,Charles A.; Brielmann,Harry; Caldwell,Timothy M.; De Lombaert,St챕phane; Hodgetts,Kevin J.; Zheng,Xiaozhang; Yoon,Taeyoung, Substituted quinazolin-4-ylamine analogues.
  24. Fossel, Eric T., Systems and methods for treatment of allergies and other indications.
  25. Fossel, Eric T., Topical composition containing ibuprofen.
  26. Fossel, Eric T., Topical composition containing naproxen.
  27. Fossel, Eric T., Topical delivery of L-arginine to cause beneficial effects.
  28. Fossel, Eric T., Topical delivery of L-arginine to cause beneficial effects.
  29. Fossel Eric T., Topical delivery of L-arginine to cause tissue warming.
  30. Fossel Eric T., Topical delivery of arginine to overcome pain.
  31. Fossel, Eric Thor, Transdermal delivery of beneficial substances effected by a hostile biophysical environment.
  32. Fossel, Eric T., Treatment of erectile dysfunction and other indications.
  33. Fossel, Eric T., Treatment of erectile dysfunction and other indications.
  34. Fossel, Eric T., Treatment of erectile dysfunction and other indications.
  35. Fossel, Eric T., Treatment of erectile dysfunction and other indications.
  36. Fossel, Eric T., Treatment of erectile dysfunction and other indications.
  37. Fossel, Eric T., Treatment of erectile dysfunction and other indications.
  38. Fossel, Eric T., Treatment of erectile dysfunction and other indications.
  39. Haas Ronald T. (West Windsor Township ; Mercer County NJ), Water soluble ibuprofen compositions and methods of making them.
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