초록 ▼

A transdermal drug applicator for application to a body for the migration of medicament through the skin into the blood stream of a patient embodies a plurality of reservoirs for containing the medicament. A battery which supplies a charge for the medicament in the applicator is disposed adjacent on

A transdermal drug applicator for application to a body for the migration of medicament through the skin into the blood stream of a patient embodies a plurality of reservoirs for containing the medicament. A battery which supplies a charge for the medicament in the applicator is disposed adjacent one side of the reservoirs with a side of the battery facing the reservoir for charging/driving the medicament. Also, a cover comprising an electrically conductive material partially encloses the battery and one side of the reservoir opposite that of the battery is exposed for contacting the skin. An electrical circuit is further provided for electrically connecting the battery to the cover, and the cover having a lip defining the periphery of the applicator for making contact with the skin when mounted on the skin leaving the battery and reservoir generally fully enclosed. An electrically conductive adhesive material coating is disposed on the underside of the lip, said reservoir renders the applicator conformable to the body contours of the patient, and when the applicator is adhered to and mounted on the skin a complete electrical circuit through the skin is formed and the medicament in the reservoir migrates out of the reservoir and through the skin into the patient\s blood stream.

대표청구항 ▼

A transdermal drug applicator for application to the body for migration of medicament through the skin to the blood stream of a patient comprising: reservoir means containing at least one medicament, battery means for supplying a current to said applicator and being close to said reservoir means for

A transdermal drug applicator for application to the body for migration of medicament through the skin to the blood stream of a patient comprising: reservoir means containing at least one medicament, battery means for supplying a current to said applicator and being close to said reservoir means for charging/driving the medicament, means for covering comprising an electrically conductive material for partially enclosing at least said reservoir means leaving the side of said reservoir means opposite that of said battery means exposed for contacting said skin, means for electrically connecting the battery means to the cover means, said cover means having lip means for making contact with said skin when mounted on said skin leaving at least said reservoir means substantially fully enclosed, an electrically conductive adhesive material coating disposed on a side of said lip means in contact with the skin when in use, and a sensing electrode and circuit means in a feedback loop mounted on said skin when in use and connected with said electrical circuit for sensing a predetermined chemical in said body and providing a control signal for regulating drug dosage at a desired level, said applicator being generally conformable to the body contour of said patient, whereby when said applicator is adhered to and mounted on said skin a complete electrical circuit through said skin is formed and a medicament in said reservoir means migrates out of said reservoir means and through said skin into the blood stream of said patient, due to the mass transfer activity attributed to at least one phenomena selected from the group consisting of electrophoresis and electro-osmosis.