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Collagen compositions for bone repair containing autogeneic marrow 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-037/02
  • A61K-035/28
  • A61F-002/28
출원번호 US-0829809 (1986-02-14)
발명자 / 주소
  • Piez Karl A. (Menlo Park CA) Weintraub Shlomo (Tel-Aviv ILX)
출원인 / 주소
  • Collagen Corporation (Palo Alto CA 02) Ramot Ltd. (Tel-Aviv ILX 03)
인용정보 피인용 횟수 : 78  인용 특허 : 2

초록

A composition which combines autogenic bone marrow with a suspension of purified atelopeptide reconstituted collagen is used to repair bone defects in mammals.

대표청구항

A method to mediate the repair of bone defects which comprises placing into said defect a composition containing reconstituted fibrillar atelopeptide collagen and autogeneic bone marrow.

이 특허에 인용된 특허 (2)

  1. Jefferies Steven R. (5802 Leith Walk Baltimore MD 21239), Bone graft material for osseous defects and method of making same.
  2. Wahlig Helmut (Darmstadt DEX) Dingeldain Elvira (Dreieich DEX) Braun Dietrich (Darmstadt-Arheilgen DEX), Medicinally useful, shaped mass of collagen resorbable in the body.

이 특허를 인용한 특허 (78)

  1. Sehl, Louis C.; Trollsas, Olof Mikael; Wallace, Donald G.; Toman, David; DeLustro, Frank A.; Schroeder, Jacqueline A.; Chu, George H., Adhesive tissue repair patch.
  2. Sehl, Louis C.; Trollsas, Olof Mikael; Wallace, Donald G.; Toman, David; DeLustro, Frank A.; Schroeder, Jacqueline A.; Chu, George H., Adhesive tissue repair patch and collagen sheets.
  3. Eyre David R. (Mercer Island WA), Assay for peptide metabolites from the amino-terminal telopeptide domain of type I collagen.
  4. Eyre David R., Assay for type I collagen carboxy-terminal telopeptide analytes.
  5. Eyre David R. (Mercer Island WA), Assay for type I collagen carboxy-terminal telopeptide analytes.
  6. Rhee,Woonza M.; DeLustro,Frank A.; Berg,Richard A., Biocompatible crosslinked composition.
  7. Alan M. Polson ; Deryl D. Swanbom ; Richard L. Dunn ; Charles P. Cox ; Richard L. Norton ; Bryan K. Lowe ; Kenneth S. Peterson, Biodegradable implant precursor.
  8. Dunn Richard L. (451 Boardwalk Dr. RLD ; Apt. 501 Fort Collins CO 80526) English James P. (2500 Melinda Cir. Birmingham AL 35214) Cowsar Donald R. (4657 Round Forest Dr. Birmingham AL 35213) Vanderbi, Biodegradable in-situ forming implants and methods of producing the same.
  9. Dunn Richard L. ; English James P. ; Cowsar Donald R. ; Vanderbilt David D., Biodegradable in-situ forming implants and methods of producing the same.
  10. Dunn Richard L. ; English James P. ; Cowsar Donald R. ; Vanderbilt David P., Biodegradable in-situ forming implants and methods of producing the same.
  11. Norton Richard L. (Fort Collins CO) Knight Stephen Michael Gregory (Fort Collins CO) Tipton Arthur J. (Birmingham AL), Biodegradable polymeric composition.
  12. Richard L. Dunn ; James P. English ; Donald R. Cowsar ; David P. Vanderbilt, Biogradable in-situ forming implants and methods of producing the same.
  13. Gower, Laurie B.; Olszta, Matthew J.; Douglas, Elliot P.; Munisamy, Sivakumar; Wheeler, Donna L., Biomimetic organic/inorganic composites.
  14. Thorne, Kevin J., Bone growth particles and osteoinductive composition thereof.
  15. Thorne, Kevin J., Bone growth particles and osteoinductive composition thereof.
  16. Akella, Rama; Garrett, Ian Ross; Wen, Hai Bo; Li, Shuliang; Acker, Dean M.; Wilhelm, Nichole, Bone void fillers.
  17. Li, Shu-Tung; Yuen, Debbie; Chen, Hui-chen, Calcium-containing bone implants.
  18. Han, Bo; Nimni, Marcel E., Composite containing collagen and elastin as a dermal expander and tissue filler.
  19. Bittmann, Pedro; Atkinson, Brent; Benedict, James J.; Ranieri, John; Whitney, Marsha L.; Chickering, Donald, Composition and device for in vivo cartilage repair.
  20. Thorne, Kevin J., Composition and process for bone growth and repair.
  21. Rhee, Woonza M.; DeLustro, Frank A.; Berg, Richard A., Composition for administration of a biologically active compound.
  22. Akella, Rama; Ranieri, John, Compositions and methods for promoting myocardial and peripheral angiogenesis.
  23. Daniloff, George Y.; Sehl, Louis C.; Trollsas, Olof Mikael; Schroeder, Jacqueline A.; Gravett, David M.; Toleikis, Philip M., Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use.
  24. Daniloff, George Y.; Sehl, Louis C.; Trollsas, Olof Mikael; Schroeder, Jacqueline A.; Gravett, David M.; Toleikis, Philip M., Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use.
  25. Daniloff, George Y.; Sehl, Louis C.; Trollsas, Olof Mikael; Schroeder, Jacqueline; Gravett, David M.; Toleikis, Philip M., Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use.
  26. Olof Mikael Trollsas ; Donald G. Wallace ; Frank A. DeLustro, Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use.
  27. Sehl, Louis C.; Trollsas, Olof Mikael; Wallace, Donald G.; Toman, David; DeLustro, Frank A.; Schroeder, Jacqueline A.; Chu, George H., Compositions and systems for forming crosslinked biomaterials and methods of preparation of use.
  28. Atkinson, Brent; Benedict, James J., Compositions for regeneration and repair of cartilage lesions.
  29. Dunn, Richard L.; Yarborough, Cody L., Coupling syringe system and methods for obtaining a mixed composition.
  30. Rhee, Woonza M.; DeLustro, Frank A.; Berg, Richard A., Cross-linked polymer compositions and methods for their use.
  31. Rhee,Woonza M.; DeLustro,Frank A.; Berg,Richard A., Crosslinked polymer compositions.
  32. Rhee Woonza M. ; DeLustro Frank A. ; Berg Richard A., Crosslinked polymer compositions and methods for their use.
  33. Rhee Woonza M. ; DeLustro Frank A. ; Berg Richard A., Crosslinked polymer compositions and methods for their use.
  34. Eyre David R. (Mercer Island WA), Detection of collagen degradation in vivo.
  35. Eyre David R., Detection of type 1 collagen degradation in vivo.
  36. Gravett, David M.; Takacs-Cox, Aniko; Toleikis, Philip M.; Maiti, Arpita; Embree, Leanne, Drug delivery from rapid gelling polymer composition.
  37. Eyre David R., Elisa kit for quantification of C-terminal telopeptides of type I collagen in human serum.
  38. Dunn,Richard L., Emulsions for in-situ delivery systems.
  39. Eyre, David R., Immunoassay for quantification of C-terminal telopeptides of type I collagen in human serum.
  40. Pfirrmann Rolf Wilhelm,CHX, Implant for use in bone surgery.
  41. Benedict, James J.; Damien, Christopher J., Implantable putty material.
  42. Benedict, James J.; Damien, Christopher J., Implantable putty material.
  43. Van Dyke, Mark E., Keratin bioceramic compositions.
  44. Van Dyke, Mark E.; Teli, Thaleia, Keratin compositions for treatment of bone deficiency or injury.
  45. Eyre David R., Kit for detecting analyte indicative of type I collagen resorption in vivo.
  46. Eyre David R., Kit for detecting analyte indicative of type II collagen resorption in vivo.
  47. Daniloff, George Y.; Ngo, Michael Huy; Trollsas, Olof Mikael; Gravett, David M.; Toleikis, Philip M., Kit for multifunctional compounds forming crosslinked biomaterials.
  48. Polson Alan M. ; Swanbom Deryl D. ; Dunn Richard L. ; Cox Charles P. ; Norton Richard L. ; Lowe Bryan K. ; Peterson Kenneth S., Method and composition for treating a bone tissue defect.
  49. Lloyd Wolfinbarger, Jr., Method and process for the production of collagen preparations from invertebrate marine animals and compositions thereof.
  50. Wolfinbarger, Jr., Lloyd, Method and process for the production of collagen preparations from invertebrate marine animals and compositions thereof.
  51. Rhee, Woonza M.; DeLustro, Frank A.; Berg, Richard A., Method for preventing the formation of adhesions following surgery or injury.
  52. Gower,Laurie B.; Olszta,Matthew J., Method for producing a mineral fiber.
  53. Gower, Laurie B.; Olszta, Matthew J.; Douglas, Elliot P.; Munisamy, Sivakumar; Wheeler, Donna L., Method for treating a bone defect with an organic/inorganic composite.
  54. Rhee, Woonza M.; DeLustro, Frank A.; Berg, Richard A., Method for treating or inhibiting the formation of adhesions following surgery or injury.
  55. Rhee Woonza M. ; DeLustro Frank A. ; Berg Richard A., Method of making crosslinked polymer matrices in tissue treatment applications.
  56. Szymaitis,Dennis W., Method of treating periodontal disease using periodontal regeneration composition.
  57. Rhee Woonza M. ; DeLustro Frank A. ; Berg Richard A., Method of using crosslinked polymer compositions in tissue treatment applications.
  58. Moehlenbruck, Jeffrey William; Ranieri, John Paul, Methods and compositions for treating intervertebral disc degeneration.
  59. Sehl, Louis C.; Trollsas, Olof Mikael; Wallace, Donald G.; Toman, David; DeLustro, Frank A.; Schroeder, Jacqueline A.; Chu, George H., Methods for tissue repair using adhesive materials.
  60. Eyre David R., Methods of monitoring patient responses to anti-resorptive therapies.
  61. McKay, William F., Osteogenic paste compositions and uses thereof.
  62. McKay,William F., Osteogenic paste compositions and uses thereof.
  63. Szymaitis, Dennis W., Periodontal regeneration composition and method of using same.
  64. Szymaitis, Dennis W., Periodontal regeneration composition and method of using same.
  65. Szymaitis,Dennis W., Periodontal regeneration composition and method of using same.
  66. Dunn Richard L. (Fort Collins CO) Tipton Arthur J. (Fort Collins CO), Polymeric compositions useful as controlled release implants.
  67. Dunn Richard L. ; Tipton Arthur J., Polymeric compositions useful as controlled release implants.
  68. Gower, Laurie B.; Olszta, Matthew J.; Douglas, Elliot P.; Munisamy, Sivakumar; Wheeler, Donna L., Process for making organic/inorganic composites.
  69. Gower, Laurie B.; Olszta, Matthew J.; Douglas, Elliot P.; Munisamy, Sivakumar; Wheeler, Donna L., Process for making organic/inorganic composites.
  70. Thorne, Kevin; Akella, Rama, Rapid isolation of osteoinductive protein mixtures from mammalian bone tissue.
  71. Eyre David R., Sandwich immunoassays for collagen type I degradation products.
  72. Eyre David R., Sandwich immunoassays for collagen type II degradation products.
  73. Nies, Berthold; Jeschke, Brigitte; Schaffner, Patricia, Structured composites as a matrix (scaffold) for the tissue engineering of bones.
  74. Rhee, Woonza M.; DeLustro, Frank A.; Berg, Richard A., Synthetic implant with nonimmunogenicity coating.
  75. Eyre David R., Synthetic peptides corresponding to telopeptide sequences of cross-linked type I collagen metabolites.
  76. Eyre David R., Synthetic peptides corresponding to telopeptide sequences of cross-linked type II collagen metabolites.
  77. Eyre, David R., Urinary assay for measuring bone resorption.
  78. Eyre, David R., Uses of synthetic peptides corresponding to telopeptide sequences of cross-linked type I collagen metabolites.
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