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Electrodes, electrode assemblies, methods, and systems for tissue stimulation 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61N-001/30
출원번호 US-0077706 (1987-07-24)
발명자 / 주소
  • Powers Whitney R. (Topsfield MA) Sisun Henry (Pawtucket RI)
출원인 / 주소
  • Trustees of Boston University (Boston MA 02)
인용정보 피인용 횟수 : 69  인용 특허 : 14

초록

A novel electrode and electrode assembly is provided which preferably uses alternating and direct electrical energy for transdermal delivery of pharmacologically active ligands and for stimulation of tissues in-vivo. Methods and systems are also disclosed which allow a broad range of therapeutic age

대표청구항

An active electrode comprising: a source of energy; a hydrophilic porous polymeric matrix which supports a confluent aqueous phase and has an initial ohmic resistance not greater than 500 ohms per square inch in the absence of electrically conductive salt solutions above 1.0% in concentration; and m

이 특허에 인용된 특허 (14)

  1. Larimore Franklin C. (Shoreview MN) Heilmann Steven M. (North St. Paul MN), Biomedical electrode.
  2. Carim Hatim M. (St. Paul MN), Cohesive nonsticky electrically conductive gel composition.
  3. Long ; Gregor Dean, Diagnostic electrode assembly.
  4. Monter Robert Paul (Centerville OH) Hall Albert Moore (Centerville OH) Cartmell James Vernon (Dayton OH), Electrode and conductor therefor.
  5. Larke ; John R. ; Barber ; Colin ; Cotterill ; David J., Electrode assemblies.
  6. Yamamoto Katsuhiro (Osaka JPX) Matsumoto Katsuo (Osaka JPX) Okada Yoshiyuki (Osaka JPX), Electrode pad.
  7. Sakurada Isoji (Kanuma JPX) Kawashima Tadasu (Utsunomiya JPX), Electrode to be used in contact with a living body.
  8. Jacobsen Stephen C. (Salt Lake City UT) Stephen Robert L. (Salt Lake City UT) Johnson R. Todd (Salt Lake City UT) Luntz Richard (Salt Lake City UT) Knutti David (Salt Lake City UT), Epidermal iontophoresis device.
  9. Jacobsen Stephen C. (Salt Lake City UT) Luntz Richard D. (Murray UT), Ion mobility limiting iontophoretic bioelectrode.
  10. Ariura Shunsuke (Matsudo JPX) Ogata Tadashi (Fuchu JPX) Kashima Norie (Tokyo JPX) Morihata Michiyo (Fuchu JPX), Iontophoresis device.
  11. Tapper Robert (175 Acari Dr. Los Angeles CA 90012), Iontophoretic burn-protection method.
  12. Lattin Gary A. (Forest Lake MN) Spevak Richard (Minneapolis MN), Iontophoretic device with reversible polarity.
  13. Webster, Henry L., Iontophoretic electrode device, method and gel insert.
  14. Bare ; Rex O. ; Robinson ; Earl F. ; Smith ; Kevin R., Non-metallic pregelled electrode.

이 특허를 인용한 특허 (69)

  1. Yanaki, Jamal S., Active electrode for transdermal medicament administration.
  2. Yanaki, Jamal S., Active transdermal medicament patch and circuit board for same.
  3. Hoenig, Peter A; Trembly, B Stuart, Apparatus and method for the treatment of infectious disease in keratinized tissue.
  4. Hoenig,Peter A.; Trembly,B. Stuart, Apparatus and method for the treatment of infectious disease in keratinized tissue.
  5. Nova Michael P. ; Lillig John E. ; Karunaratne Kanchana Sanjaya Gunesekera ; Ewing William ; Satoda Yozo ; Potash Hanan, Automated sorting system for matrices with memory.
  6. Barman,Shikha P.; Schramm,Helice A.; Warner,Nicholas F., Biocompatible chemically crosslinked hydrogels for glucose sensing.
  7. Weaver James C. (Sudbury MA) Powell Kevin T. (Boston MA) Langer ; Jr. Robert S. (Newton MA), Control of transport of molecules across tissue using electroporation.
  8. Axelgaard Jens, Current-controlling electrode.
  9. Axelgaard Jens, Current-controlling electrode.
  10. Owen, James M.; Fincke, Randall W.; O'Leary, James P.; Totman, Mark H., Defibrillation system.
  11. Owen James M. ; Fincke Randall W. ; O'Leary James P. ; Totman Mark H., Defibrillation system having segmented electrodes.
  12. Freed, Marcy L., Device and method for treating dysphagia with electrical stimulation.
  13. Pawlowicz, III, John S., Devices and methods for transcutaneous electrical neural stimulation.
  14. Brogan, Michael S.; Edsberg, Laura E.; Kalinowski, Douglas P., Electrical stimulation unit and waterbath system.
  15. Brogan, Michael S.; Edsberg, Laura E.; Kalinowski, Douglas P., Electrical stimulation unit and waterbath system.
  16. Dunlay, Ed; Kretschmer, Tim, Electrodes for use in treatment of oropharyngeal disorders by application of neuromuscular electrical stimulation.
  17. Riddle Thomas A. ; McNichols Larry A. ; Badzinski John D., Electrotransport delivery device with voltage boosting circuit.
  18. Riddle, Thomas A.; McNichols, Larry A.; Badzinski, John D., Electrotransport delivery device with voltage boosting circuit.
  19. Riddle, Thomas A.; McNichols, Larry A.; Badzinski, John D., Electrotransport delivery device with voltage boosting circuit.
  20. Murdock Thomas O., Electrotransport drug delivery reservoirs containing inert fillers.
  21. Akiyama, Hidero; Nakayama, Mizuo; Matsumura, Takehiko; Matsumura, Akihiko, Iontophoresis device.
  22. Kanamura, Kiyoshi; Kosiba, Nobuharu; Nakayama, Mizuo; Matsumura, Takehiko; Akiyama, Hidero; Matsumura, Akihiko, Iontophoresis device.
  23. Atanasoska Ljiljana, Iontophoresis electrode.
  24. Maulding, Hawkins V.; Siverly, James R., Iontophoretic delivery of peptides.
  25. Keusch,Preston; Vilambi,NRK; Eliash,Bruce Michael, Iontophoretic drug delivery device and reservoir and method of making same.
  26. Tapper Robert, Iontophoretic treatment system.
  27. Tapper Robert, Iontophoretic treatment system.
  28. Tapper Robert, Iontophoretic treatment system.
  29. Tapper, Robert, Iontophoretic treatment system.
  30. Tapper, Robert, Iontophoretic treatment system.
  31. Tapper, Robert, Iontophoretic treatment system.
  32. Chien Yie W. (North Brunswick NJ) Kong-Jiann Li John (Plainsboro NJ) Liu Jue-Chen (East Brunswick NJ) Shi Wei-Min (Piscataway NJ) Siddiqui Ovais (Piscataway NJ) Sun Ying (King of Prussia PA), Iontotherapeutic device and process and iontotherapeutic unit dose.
  33. Chien Yie W. ; Li John Kong-Jiann ; Liu Jue-Chen ; Shi Wei-Min ; Siddiqui Ovais,AUX ; Sun Ying,CAX, Iontotherapeutic device and process and iontotherapeutic unit dose.
  34. Gyory J. Richard ; Haak Ronald P., Layered rate controlling membranes for use in an electrotransport device.
  35. Owen, James M.; Fincke, Randall W.; O'Leary, James P.; Totman, Mark H., Long term wear electrode for defibrillation system.
  36. Nova Michael P. ; Parandoosh Zahra ; Senyei Andrew E. ; Xiao Xiao-Yi ; David Gary S. ; Satoda Yozo ; Zhao Chanfeng ; Potash Hanan, Matrices with memories and uses thereof.
  37. Phipps Joseph B., Method and apparatus for controlled environment electrotransport.
  38. Phipps Joseph B., Method and apparatus for controlled environment electrotransport.
  39. Phipps Joseph B. (Plymouth MN), Method and apparatus for controlled environment electrotransport.
  40. Mitragotri, Samir S.; Kost, Joseph; Kellogg, Scott C.; Warner, Nicholas F.; Elstrom, Tuan A., Method and apparatus for enhancement of transdermal transport.
  41. Mitragotri, Samir S.; Kost, Joseph; Kellogg, Scott C.; Warner, Nicholas F; Elstrom, Tuan A, Method and apparatus for enhancement of transdermal transport.
  42. Freed,Marcy L.; Freed,Leonard A.; Christian,Michael O.; Tucker,Howard; Kotton,Bernard; Beytas,Erol M.; Dunlay,Ed; Kretschmer,Tim; Asmar,Marie, Method and apparatus for treating oropharyngeal disorders with electrical stimulation.
  43. Silverstone, Leon M., Method and apparatus for treatment of viral diseases.
  44. Silverstone, Leon M., Method and apparatus for treatment of viral diseases.
  45. Silverstone,Leon M., Method and apparatus for treatment of viral diseases.
  46. Edward W. Knowlton, Method for controlled contraction of collagen in fibrous septae in subcutaneous fat layers.
  47. Guy, Richard; Rao, Girish, Method for the iontophoretic non-invasive determination of the in vivo concentration level of an inorganic or organic substance.
  48. Guy, Richard; Rao, Girish; Cullander, Christopher; Hinz, Robert S.; Glikfeld, Peretz, Method for the iontophoretic non-invasive determination of the in vivo concentration level of an inorganic or organic substance.
  49. Guy Richard ; Rao Girish ; Glikfeld Peretz,ILX ; Cullander Christopher ; Hinz Robert S., Method for the iontophoretic non-invasive determination of the in vivo concentration level of glucose.
  50. Bureau, Michel; Mir, Lluis; Scherman, Daniel, Method for transferring nucleic acid into multicelled eukaryotic organism cells and combination therefor.
  51. Bureau, Michel; Mir, Lluis; Scherman, Daniel, Method for transferring nucleic acid into striated muscles.
  52. Hakky Said ; Hakki A-Hamid, Non-invasive bodily fluid withdrawal and monitoring system.
  53. Silverstone, Leon M., Non-invasive method and apparatus for the treatment of viral infections.
  54. Kraft, Edward R.; Kulp, Gabriela, Photokinetic delivery of biologically active substances using pulsed incoherent light.
  55. Kraft,Edward R.; Kulp,Gabriela, Photokinetic delivery of biologically active substances using pulsed incoherent light.
  56. Murdock, Thomas O., Polymeric foam reservoirs for an electrotransport delivery device.
  57. Mosk, Michael D.; Breen, Michael M., Process for the stimulation of production of extracellular dermal proteins in human tissue.
  58. Michael P. Nova ; Andrew E. Senyei, Remotely programmable matrices with memories.
  59. Nova Michael P. ; Senyei Andrew E., Remotely programmable matrices with memories.
  60. Nova Michael P. ; Senyei Andrew E. ; David Gary S., Remotely programmable matrices with memories.
  61. Soichiro Kawakami JP; Tomoya Yamamoto JP; Hironao Kimura JP, Secondary battery having an ion conductive member and manufacturing process thereof.
  62. Chuang, Han; Eslava, Juan P.; Hurley, James P.; Ghosh, Debashis; Krystyniak, Keith; Kellogg, Scott C., Skin permeation device for analyte sensing or transdermal drug delivery.
  63. Chuang, Han; Eslava, Juan P.; Hurley, James P.; Ghosh, Debashis; Krystyniak, Keith; Kellogg, Scott C., Skin permeation device for analyte sensing or transdermal drug delivery.
  64. Tapper Robert, Sweat control system.
  65. Kellogg, Scott C.; Chuang, Han, System and method for analyte sampling and analysis with hydrogel.
  66. Custer,Linda; Elstrom,Tuan A.; Kellogg,Scott C.; Kost,Joseph; Warner,Nicholas F., System, method, and device for non-invasive body fluid sampling and analysis.
  67. Carter, Darrick; Hoyt, Joshua K.; Thorne, James; Seitz, Forrest, Systems, devices, and methods for powering and/or controlling devices, for instance transdermal delivery devices.
  68. Chuang, Han; Hurley, James P.; Kost, Joseph, Transdermal analyte monitoring systems and methods for analyte detection.
  69. Siegel, Robert J.; Birnbaum, Yochai; Luo, Huai, Ultrasonic bath to increase tissue perfusion.
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