초록 ▼

A method of treating a patient with liquid medicament under circumstances where intravenous injection is not practical but the fast response time of an intravenous injection is desirable, including the treatment of individuals undergoing heart attack symptoms with t-PA. The method comprises the step

A method of treating a patient with liquid medicament under circumstances where intravenous injection is not practical but the fast response time of an intravenous injection is desirable, including the treatment of individuals undergoing heart attack symptoms with t-PA. The method comprises the steps of injecting the liquid medicament t-PA preferably with a blood absorption enhancing agent such as hydroxylamine hydrochloride into the muscle tissue of the patient, applying to the patient which has received the injection repeated blood flow stimulating cycles, each of which includes a period of electrical stimulus during which the muscle tissue which has received the injection tenses followed by a period of no electrical stimulus during which the muscle tissue which received the injection is allowed to relax inducing enhanced blood flow within the muscle tissue, and continuing the application of the repeated blood flow stimulating cycles until the injected liquid medicament has been sufficiently absorbed into the enhanced blood flow to achieve a desired possible patient response of reperfusion and apparatus for carrying out the method.

대표청구항 ▼

Apparatus for treating a patient with a liquid medicament for purposes of establishing reperfusion under circumstances where intravenous injection is not practical but the fast response time of an intravenous injection is desirable comprising an automatic injector assembly including outer housing me

Apparatus for treating a patient with a liquid medicament for purposes of establishing reperfusion under circumstances where intravenous injection is not practical but the fast response time of an intravenous injection is desirable comprising an automatic injector assembly including outer housing means, medicament cartridge means mounted within said outer housing means in a storage position, said medicament cartridge means including a hypodermic needle, a plurality of medicament containers, and a plurality of medicament ingredients in said medicament containers, moving means within said outer housing means for effecting movement of said medicament cartridge means out of said storage position, mixing means within said outer housing means operable when said medicament cartridge means is moved out of said storage position for mixing the medicament ingredients to form a liquid medicament, said moving means including stressed spring means releasable for effecting movement of said hypodermic needle outwardly of said outer housing means into the muscle tissue of the patient and said mixed liquid medicament outwardly through said needle into the muscle tissue of the patient, said mixed liquid medicament including a clot selective coronary thrombolytic agent and a blood absorption enhancing agent.