$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

Bone morphogenetic agents 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C07G-007/00
  • C09H-001/00
  • A23J-001/00
출원번호 US-0763479 (1985-08-07)
발명자 / 주소
  • Urist Marshall R. (Pacific Palisades CA)
출원인 / 주소
  • The Regents of the University of California (Berkeley CA 02)
인용정보 피인용 횟수 : 112  인용 특허 : 6

초록

The production and isolation of bone morphogenetic peptide agents displaying the osteoinductive and immunoreactive activity of bone morphogenetic protein (BMP) and deriving from natural, synthetic or recombinant DNA sources, and said agents.

대표청구항

A bone morphogenetic peptide having an amino acid sequence, said sequence selected from the group consisting of amino acid sequences of peptide fragments (BMP-p) having a relative molecular weight (Mr) of about 4K to about 7K and derived from proteolysis of bone morphogenetic protein (BMP), said pep

이 특허에 인용된 특허 (6)

  1. Jefferies Steven R. (5802 Leith Walk Baltimore MD 21239), Bone graft material for osseous defects and method of making same.
  2. Urist Marshall R. (Pacific Palisades CA), Bone morphogenetic protein.
  3. Urist Marshall R. (Pacific Palisade CA), Bone morphogenetic protein process.
  4. Spilburg Curtis A. (St. Louis MO) Schuck James M. (Chesterfield MO), Novel glycoproteins from bovine cartilage.
  5. Seyedin Saeid (Mt. View CA) Thomas Thomas (Palo Alto CA), Partially purified osteogenic factor and process for preparing same from demineralized bone.
  6. Aoki Nobuo (Tokyo OK JPX) Kurosawa Shinichiro (Oklahoma City OK), Thrombin-binding substance and process for its production.

이 특허를 인용한 특허 (112)

  1. Michelson,Gary Karlin, Apparatus and method for anterior spinal stabilization.
  2. Michelson, Gary Karlin, Apparatus for insertion into an implantation space.
  3. Wang,Elizabeth A.; Wozney,John M.; Rosen,Vicki A., BMP products.
  4. Wang Elizabeth A. (Carlisle MA) Wozney John M. (Hudson MA) Rosen Vicki (Brookline MA), BMP-2 products.
  5. Rosen Vicki A. ; Wozney John M. ; Celeste Anthony J. ; Thies R. Scott ; Song Jeffrey R., BMP-9 compositions.
  6. Rosen Vicki A. ; Wozney John M. ; Celeste Anthony J. ; Thies Scott R. ; Song Jeffrey R., BMP-9 compositions.
  7. Alan M. Polson ; Deryl D. Swanbom ; Richard L. Dunn ; Charles P. Cox ; Richard L. Norton ; Bryan K. Lowe ; Kenneth S. Peterson, Biodegradable implant precursor.
  8. Dunn Richard L. (Fort Collins CO) Tipton Arthur J. (Fort Collins CO) Southard George L. (Fort Collins CO) Rogers Jack A. (Fort Collins CO), Biodegradable polymer composition.
  9. Norton Richard L. (Fort Collins CO) Knight Stephen Michael Gregory (Fort Collins CO) Tipton Arthur J. (Birmingham AL), Biodegradable polymeric composition.
  10. Hewick,Rodney M.; Wang,Jack H.; Wozney,John M.; Celeste,Anthony J., Bone and cartilage inductive proteins.
  11. Nimni, Marcel E., Bone graft material incorporating demineralized bone matrix and lipids.
  12. Nimni,Marcel E., Bone graft material incorporating demineralized bone matrix and lipids.
  13. Thorne, Kevin J., Bone growth particles and osteoinductive composition thereof.
  14. Behnam, Keyvan, Bone matrix compositions and methods.
  15. Behnam, Keyvan, Bone matrix compositions and methods.
  16. Behnam, Keyvan; Cioffi, Christopher, Bone matrix compositions and methods.
  17. Behnam, Keyvan; Cioffi, Christopher, Bone matrix compositions and methods.
  18. Behnam, Keyvan; Wei, Guobao; Forsyth, Nanette, Bone matrix compositions and methods.
  19. Behnam, Keyvan; Wei, Guobao; Forsyth, Nanette; Boyce, Todd M.; Shimp, Lawrence A., Bone matrix compositions and methods.
  20. Wei, Guobao; Behnam, Keyvan; Forsyth, Nanette, Bone matrix compositions having nanoscale textured surfaces.
  21. Wei, Guobao; Behnam, Keyvan; Forsyth, Nanette, Bone matrix compositions having nanoscale textured surfaces.
  22. Hair, Gregory A.; Boden, Scott D., Bone mineralization proteins, DNA, vectors expression systems.
  23. Gregory A. Hair ; Scott D. Boden, Bone mineralization proteins, DNA, vectors, expression systems.
  24. Hair Gregory A. ; Boden Scott D., Bone mineralization proteins, DNA, vectors, expression systems.
  25. Hair, Gregory A.; Boden, Scott D., Bone mineralization proteins, DNA, vectors, expression systems.
  26. Thies R. Scott ; Song Jeffrey J., Bone morphogenetic protein (BMP)-9 compositions and their uses.
  27. Kiefer Michael C. (Clayton CA) Masiarz Frank R. (San Francisco CA) Barr Philip J. (Oakland CA), Bone morphogenetic protein expression and DNA.
  28. Elizabeth A. Wang ; John M. Wozney ; Vicki Rosen, Bone morphogenetic protein-3 and compositions.
  29. Akella, Rama; Garrett, Ian Ross; Wen, Hai Bo; Li, Shuliang; Acker, Dean M.; Wilhelm, Nichole, Bone void fillers.
  30. Li,Rebecca H.; Seeherman,Howard, Calcium phosphate delivery vehicles for osteoinductive proteins.
  31. Thorne, Kevin J., Composition and process for bone growth and repair.
  32. Baird, Andrew; Gonzalez, Ana Maria; Logan, Ann; Berry, Martin, Compositions and methods for delivery of agents for neuronal regeneration and survival.
  33. Clancy,Brian; Pittman,Debra; Seeherman,Howard, Compositions and methods for systemic administration of sequences encoding bone morphogenetic proteins.
  34. Atkinson, Brent; Benedict, James J., Compositions for regeneration and repair of cartilage lesions.
  35. Dunn, Richard L.; Yarborough, Cody L., Coupling syringe system and methods for obtaining a mixed composition.
  36. Hewick Rodney M. (Lexington MA) Wang Jack H. (Lexington MA) Wozney John M. (Hudson MA) Celeste Anthony J. (Hudson MA), DNA encoding and methods for producing BMP-8 proteins.
  37. Wozney,John M.; Celeste,Anthony J.; Thies,R. Scott; Yamaji,Noboru, DNA molecules encoding BMP receptor proteins.
  38. Wang Elizabeth A. (Carlisle MA) Wozney John M. (Hudson MA) Rosen Vicki (Brookline MA), DNA sequences encoding osteoinductive products.
  39. Wei, Guobao; Behnam, Keyvan; Forsyth, Nanette; Winterbottom, John; Beisser, James; Boyce, Todd M., Delivery system.
  40. Wei, Guobao; Behnam, Keyvan; Forsyth, Nanette; Winterbottom, John; Beisser, James; Boyce, Todd M.; Berven, Sigurd H.; Betz, Randal R.; O'Brien, Michael F.; Shelokov, Alexis P., Delivery system.
  41. Wei, Guobao; Behnam, Keyvan; Forsyth, Nanette; Winterbottom, John; Beisser, James; Boyce, Todd M.; Attawia, Mohamed; Richards, Cristy J.; Shimp, Lawrence A., Delivery system attachment.
  42. Wei, Guobao; Behnam, Keyvan; Forsyth, Nanette; Winterbottom, John; Beisser, James; Boyce, Todd; Attawia, Mohamed; Richards, Cristy J.; Shimp, Lawrence A., Delivery system attachment.
  43. Wei, Guobao; Boyce, Todd M.; Shimp, Lawrence A., Delivery system cartridge.
  44. Betz, Randal R.; Boden, Scott; Gupta, Munish Chandra; O'Brien, Michael F.; Sandhu, Harvinder; Shelokov, Alexis; Sybert, Daryl R.; Vaccaro, Alexander; Wei, Guobao; Boyce, Todd M.; Cohen, Robert; Richards, Cristy; Shimp, Lawrence A., Delivery systems, tools, and methods of use.
  45. Behnam, Keyvan; Wei, Guobao; Beisser, James, Demineralized bone matrix compositions and methods.
  46. Behnam, Keyvan; Wei, Guobao; Beisser, James A., Demineralized bone matrix compositions and methods.
  47. Michelson, Gary Karlin, Device and method for locking a screw with a bendable plate portion.
  48. Michelson, Gary K., Dynamic plate system having moveable segments.
  49. Michelson, Gary K., Dynamic, modular, multilock anterior cervical plate system having detachably fastened assembleable and moveable segments and instrumentation for installation thereof.
  50. Michelson, Gary K., Dynamic, modular, single-lock anterior cervical plate system having assembleable and moveable segments and instrumentation for installation thereof.
  51. Dunn,Richard L., Emulsions for in-situ delivery systems.
  52. Leonard, Edward F.; Reich, Ilan K.; Cortell, Stanley, Fluid separation devices, systems and methods.
  53. Bonadio Jeffrey ; Goldstein Steven A., Gene transfer into bone cells and tissues.
  54. McKay, William F., Highly mineralized osteogenic sponge compositions and uses thereof.
  55. McKay, William F., Highly-mineralized osteogenic sponge compositions and uses thereof.
  56. McKay, William F., Highly-mineralized osteogenic sponge compositions, and uses thereof.
  57. Michelson, Gary K., Implant with openings adapted to receive bone screws.
  58. Michelson, Gary K., Implant with openings adapted to receive bone screws.
  59. Michelson, Gary K., Implant with openings adapted to receive bone screws.
  60. Michelson,Gary K., Implant with trailing end adapted to receive bone screws.
  61. Goldstein Steven A. ; Bonadio Jeffrey, In vivo gene transfer methods for wound healing.
  62. Li, Rebecca; Seeherman, Howard; Kim, Hyun, Injectable calcium phosphate solid rods and pastes for delivery of osteogenic proteins.
  63. Li, Rebecca; Seeherman, Howard; Kim, Hyun, Injectable calcium phosphate solid rods and pastes for delivery of osteogenic proteins.
  64. Kim,Hyun; Li,Rebecca; Pavesio,Alessandra; Callegaro,Lanfranco; Seeherman,Howard; Wozney,John, Injectable carrier formulations of hyaluronic acid derivatives for delivery of osteogenic proteins.
  65. Michelson, Gary K., Instrumentation for use with dynamic multilock anterior cervical plate system having non-detachably fastened and moveable segments.
  66. Michelson,Gary K., Instrumentation for use with dynamic single-lock anterior cervical plate system having non-detachably fastened and moveable segments.
  67. Michelson, Gary Karlin, Interbody spinal fusion implants.
  68. Michelson, Gary K., Interbody spinal implant with trailing end adapted to receive bone screws.
  69. Chern, Rey T.; Zingerman, Joel R., Liquid polymeric compositions for controlled release of bioactive substances.
  70. Polson Alan M. ; Swanbom Deryl D. ; Dunn Richard L. ; Cox Charles P. ; Norton Richard L. ; Lowe Bryan K. ; Peterson Kenneth S., Method and composition for treating a bone tissue defect.
  71. Michelson, Gary K., Method for installation of dynamic anterior cervical plate system having moveable segments.
  72. Michelson, Gary K., Method for installation of dynamic, single-lock anterior cervical plate system having non-detachably fastened and moveable segments.
  73. Michelson, Gary K., Method for installation of dynamic, single-lock anterior cervical plate system having non-detachably fastened and moveable segments.
  74. Michelson, Gary K., Method for installing dynamic multilock anterior cervical plate system having detachably fastened and moveable segments.
  75. Michelson,Gary K., Method for installing dynamic, modular, multilock anterior cervical plate system having detachably fastened assembleable and moveable segments.
  76. Michelson,Gary K., Method for installing dynamic, modular, single-lock anterior cervical plate system having assembleable and moveable segments.
  77. Peel, Sean A. F.; Clokie, Cameron M. L.; Turner, Jeffrey D., Method of enhancing recombinant protein production.
  78. Shimp, Lawrence A.; Wei, Guobao; Behnam, Keyvan, Method of treating bone tissue.
  79. Zhang,Renwen; Peluso,Diane; Morris,Elisabeth, Methods and compositions for healing and repair of articular cartilage.
  80. Bonadio Jeffrey ; Goldstein Steven A., Methods and compositions for multiple gene transfer into bone cells.
  81. Hunziker Ernst B. (Riedholz CHX), Methods and compositions for the treatment and repair of defects or lesions in cartilage or bone.
  82. Rutherford,Bruce; Somogyi,Christopher; White,Clinton; Rabins,Erick, Methods for treating dental conditions using tissue scaffolds.
  83. Leonard, Edward F.; West, Alan C.; Shapley, Nina C.; Tang, Zhongliang, Methods of blood-based therapies having a microfluidic membraneless exchange device.
  84. Wang,Elizabeth; Wozney,John M.; Rosen,Vicki A., Methods of treatment of periodontal disease.
  85. Bonadio, Jeffrey; Yin, Wushan, Methods of using latent TGF-β binding proteins.
  86. Oppermann,Hermann; Kuberasampath,Thangavel; Rueger,David C.; Ozkaynak,Engin, Nucleic acid molecules encoding osteogenic proteins.
  87. Oppermann Hermann ; Kuberasampath Thangavel ; Rueger David C. ; Ozkaynak Engin, Nucleotide sequences encoding osteogenic proteins.
  88. Damien Christopher J. (Denver CO) Benedict James J. (Golden CO) Poser James W. (Lawrenceville NJ), Osteogenic product and process.
  89. Behnam, Keyvan; Forsyth, Nanette; Russell, James; Winterbottom, John; Boyce, Todd, Osteoinductive demineralized cancellous bone.
  90. Behnam, Keyvan; Forsyth, Nanette; Russell, James; Winterbottom, John; Boyce, Todd, Osteoinductive demineralized cancellous bone.
  91. Agrawal C. Mauli ; Athanasiou Kyriacos A., Permeable compositions and methods for their preparation.
  92. Thorne, Kevin; Akella, Rama, Rapid isolation of osteoinductive protein mixtures from mammalian bone tissue.
  93. Israel, David; Wolfman, Neil M., Recombinant bone morphogenetic protein heterodimers, compositions and methods of use.
  94. Bonadio Jeffrey ; Yin Wushan, Recombinant production of latent TGF-beta binding protein-3 (LTBP-3).
  95. Wei, Guobao; Boyce, Todd M.; Cohen, Robert; Richards, Cristy; Shimp, Lawrence A., Segmented delivery system.
  96. Wei, Guobao; Boyce, Todd M.; Cohen, Robert; Richards, Cristy; Shimp, Lawrence A., Segmented delivery system.
  97. Gary Karlin Michelson, Spinal implant with bone screws.
  98. Clokie, Cameron M. L.; Peel, Sean A. F., System and method for multiphasic release of growth factors.
  99. Peel, Sean A. F.; Clokie, Cameron M. L., System and method for multiphasic release of growth factors.
  100. Leonard, Edward F.; West, Alan C.; Shapley, Nina C.; Tang, Zhongliang, Systems and methods for membraneless dialysis.
  101. Leonard, Edward F.; West, Alan C.; Shaplely, Nina C.; Tang, Zhongliang, Systems and methods of blood-based therapies having a microfluidic membraneless exchange device.
  102. Leonard, Edward F.; West, Alan C.; Shapley, Nina C.; Tang, Zhongliang, Systems and methods of blood-based therapies having a microfluidic membraneless exchange device.
  103. Leonard, Edward F.; West, Alan C.; Aucoin, Christian P.; Nanne, Edgar E., Systems and methods of microfluidic membraneless exchange using filtration of extraction outlet streams.
  104. Leonard, Edward F.; West, Alan C.; Aucoin, Christian Paul; Nanne, Edgar E., Systems and methods of microfluidic membraneless exchange using filtration of extraction outlet streams.
  105. Leonard, Edward F.; West, Alan C.; Aucoin, Christian Paul; Nanne, Edgar E., Systems and methods of microfluidic membraneless exchange using filtration of extraction outlet streams.
  106. Leonard, Edward F.; West, Alan C.; Aucoin, Christian Paul; Nanne, Edgar E., Systems and methods of microfluidic membraneless exchange using filtration of extraction outlet streams.
  107. Leonard, Edward F.; West, Alan C.; Aucoin, Christian Paul; Nanne, Edgar E., Systems and methods of microfluidic membraneless exchange using filtration of extraction outlet streams.
  108. Leonard, Edward F.; West, Alan C.; Aucoin, Christian Paul; Nanne, Edgar E., Systems and methods of microfluidic membraneless exchange using filtration of extraction outlet streams.
  109. Celeste,Anthony J.; Wozney,John M.; Rosen,Vicki A.; Wolfman,Neil M.; Thomsen,Gerald H.; Melton,Douglas A., Tendon-inducing compositions.
  110. Celeste,Anthony J.; Wozney,John M.; Rosen,Vicki A.; Wolfman,Neil M.; Thomsen,Gerald H.; Melton,Douglas A., Tendon-inducing methods.
  111. Stone Roger Lee (Hamilton OH), Therapeutic compositions for osteoinduction.
  112. Agrawal C. Mauli ; Athanasiou Kyriacos A., Variable permeability bone implants, methods for their preparation and use.
섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트

맨위로