초록 ▼

The disclosure herein describes a controlled release tablet which includes a core formed of a solid mixture having a hydrophilic releasable agent; the core has a central hole and is coated, on all faces except that bordering the hole with a hydrophobic material. The thickness of the core gradually i

The disclosure herein describes a controlled release tablet which includes a core formed of a solid mixture having a hydrophilic releasable agent; the core has a central hole and is coated, on all faces except that bordering the hole with a hydrophobic material. The thickness of the core gradually increases from the hole to the outer border, this being a factor in the rate of release of the mixture through the hole. One application of such a tablet is for the controlled release of a therapeutic agent in the field of drug delivery systems.

대표청구항 ▼

A pharmaceutical tablet comprising: a body having a disc-like configuration with a cylindrical hole extending centrally therethrough, said body including: a core formed of a compressed mixture of a therapeutic agent and of a biocompatible polymeric material, said core being defined by centrally tape

A pharmaceutical tablet comprising: a body having a disc-like configuration with a cylindrical hole extending centrally therethrough, said body including: a core formed of a compressed mixture of a therapeutic agent and of a biocompatible polymeric material, said core being defined by centrally tapering upper and lower annular faces and by inner and outer cylindrical faces; and a coating of impermeable material covering said upper and lower annular faces and said outer cylindrical face; said agent being released from said hole at a biological site of absorption.