$\require{mediawiki-texvc}$
  • 검색어에 아래의 연산자를 사용하시면 더 정확한 검색결과를 얻을 수 있습니다.
  • 검색연산자
검색도움말
검색연산자 기능 검색시 예
() 우선순위가 가장 높은 연산자 예1) (나노 (기계 | machine))
공백 두 개의 검색어(식)을 모두 포함하고 있는 문서 검색 예1) (나노 기계)
예2) 나노 장영실
| 두 개의 검색어(식) 중 하나 이상 포함하고 있는 문서 검색 예1) (줄기세포 | 면역)
예2) 줄기세포 | 장영실
! NOT 이후에 있는 검색어가 포함된 문서는 제외 예1) (황금 !백금)
예2) !image
* 검색어의 *란에 0개 이상의 임의의 문자가 포함된 문서 검색 예) semi*
"" 따옴표 내의 구문과 완전히 일치하는 문서만 검색 예) "Transform and Quantization"

통합검색

도움말도움말
상세검색 다국어 입력

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

특허 상세정보

MyON담기
내보내기 페이스북 공유 카카오톡 공유

Porous microspheres for drug delivery and methods for making same

특허상세정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판) A61K-009/16    A61K-009/50    A61K-009/52    B01J-013/02   
미국특허분류(USC) 424/491 ; 34/5 ; 264/46 ; 424/486
출원번호 US-0846513 (1986-03-31)
발명자 / 주소
출원인 / 주소
인용정보 피인용 횟수 : 253  인용 특허 : 2
초록

Controlled release drug delivery systems comprised of spherical microporous polymeric network of interconnecting channels containing pore incorporated drugs or other agents wherein the drugs or agents are confined within the pore channel are described. Also disclosed are processing parameters in connection with the novel method of the invention for obtaining drug delivery systems especially suited for parenteral as well as oral administration.

대표
청구항
▼

A method for preparing a relatively homogenous essentially spherical microporous polymeric network of interconnecting channels containing a pore incorporated agent confined essentially completely inside the channels comprising preparing an agentpolymer-solvent dispersed first phase, dispersing said first phase in a continuous solvent second phase to obtain a suspension, removing solvent from said suspension by freeze drying, or dilution-extraction-precipitation and recovering said microporous polymeric network. A drug delivery system comprising a spheric...

이 특허에 인용된 특허 (2)

  1. Morishita Masataka (Shizuoka JA) Inaba Yoshihito (Shizuoka JA) Fukushima Mitsuru (Shizuoka JA) Kobari Sadami (Shizuoka JA) Nagata Akiho (Shizuoka JA) Abe Jinnosuke (Shizuoka JA). Preparation of microcapsules. USP1976033943063.
  2. Fong, Jones W.. Process for preparation of microspheres. USP1983054384975.

이 특허를 인용한 특허 피인용횟수: 253

  1. Gough, Edward J.; Stein, Alan A.; Edwards, Stuart D.. Ablation apparatus and method. USP2014058734439.
  2. Barrows, Thomas H.; Lewis, Terry W.; Truong, Myhanh T.; Scholz, Matthew T.. Adhesive sealant composition. USP200510RE38827.
  3. Barrows, Thomas H.; Lewis, Terry W.; Truong, Myhanh T.; Scholz, Matthew T.. Adhesive sealant composition. USP200306RE38158.
  4. David A. Edwards ; Giovanni Caponetti ; Jeffrey S. Hrkach ; Noah Lotan IL; Justin Hanes ; Abdellaziz Ben-Jebria ; Robert S. Langer. Aerodynamically light particles for pulmonary drug delivery. USP2002066399102.
  5. Edwards David A. ; Caponetti Giovanni,ITX ; Hrkach Jeffrey S. ; Lotan Noah,ILX ; Hanes Justin ; Ben-Jebria Abdell Aziz ; Langer Robert S.. Aerodynamically light particles for pulmonary drug delivery. USP2000106136295.
  6. Edwards David A. ; Caponetti Giovanni,ITX ; Hrkach Jeffrey S. ; Lotan Noah,ILX ; Hanes Justin ; Ben-Jebria Abdell Aziz ; Langer Robert S.. Aerodynamically light particles for pulmonary drug delivery. USP1999025874064.
  7. Edwards, David A.; Caponetti, Giovanni; Hrkach, Jeffrey S.; Lotan, Noah; Hanes, Justin; Ben-Jebria, Abdellaziz; Langer, Robert S.. Aerodynamically light particles for pulmonary drug delivery. USP2005096942868.
  8. Edwards, David A.; Caponetti, Giovanni; Hrkach, Jeffrey S.; Lotan, Noah; Hanes, Justin; Ben-Jebria, Abdellaziz; Langer, Robert S.. Aerodynamically light particles for pulmonary drug delivery. USP2003106635283.
  9. Edwards, David A.; Caponetti, Giovannia; Hrkach, Jeffrey S.; Lotan, Noah; Hanes, Justin; Ben-Jebria, Abdell Aziz; Langer, Robert S.. Aerodynamically light particles for pulmonary drug delivery. USP2003016503480.
  10. Edwards, David A.; Caponetti, Giovannia; Hrkach, Jeffrey S.; Lotan, Noah; Hanes, Justin; Ben-Jebria, Abdell Aziz; Langer, Robert S.. Aerodynamically light particles for pulmonary drug delivery. USP2005126977087.
  11. David A. Edwards ; Giovanni Caponetti ; Jeffrey S. Hrkach ; Noah Lotan IL; Justin Hanes ; Robert S. Langer ; Abdellaziz Ben-Jebria. Amorphous porous particles for deep lung delivery. USP2002096447752.
  12. Zhang, Liangfang; Radovic-Moreno, Aleksandar F.; Gu, Frank X.; Alexis, Frank; Langer, Robert S.; Farokhzad, Omid C.. Amphiphilic compound assisted nanoparticles for targeted delivery. USP2016059333179.
  13. Lillard, James W.; Singh, Shailesh; Singh, Rajesh. Anti-CCL25 and anti-CCR9 antibodies for the prevention and treatment of cancer and cancer cell migration. USP2016019233120.
  14. Lillard, James W.; Singh, Rajesh; Singh, Shailesh. Anti-CXCL13 and anti-CXCR5 antibodies for the prevention and treatment of cancer and cancer cell migration. USP2013088512701.
  15. Mayes, Sarah; Schmidt, Christine E.. Anti-adhesive barrier membrane using alginate and hyaluronic acid for biomedical applications. USP2015089095558.
  16. Mayes, Sarah; Schmidt, Christine E.. Anti-adhesive barrier membrane using alginate and hyaluronic acid for biomedical applications. USP2017059656001.
  17. Lillard, James W.; Singh, Shailesh; Stiles, Jonathan K.. Anti-chemokine and associated receptors antibodies for inhibition of growth of neoplasms. USP2012018097250.
  18. Yi, Chin-Feng; Gosiewska, Anna; Roweton, Susan. Bioabsorbable bag containing bioabsorbable materials of different bioabsorption rates for tissue engineering. USP2003126656488.
  19. Edith Mathiowitz ; Donald E. Chickering, III ; Jules Serge Jacob. Bioadhesive microspheres and their use as drug delivery and imaging systems. USP2002046365187.
  20. Mathiowitz Edith ; Chickering ; III Donald ; Jacob Jules S.. Bioadhesive microspheres and their use as drug delivery and imaging systems. USP2001056235313.
  21. Mathiowitz Edith ; Chickering Donald ; Jacob Jules Serge. Bioadhesive microspheres and their use as drug delivery and imaging systems. USP2001046217908.
  22. Athanasiou Kyriacos A. ; Boyan Barbara D.. Biodegradable implant. USP1999035876452.
  23. Ng, Steven Y.; Heller, Jorge. Bioerodible poly (orthoesters) from dioxolane-based diketene acetals. USP2004116822000.
  24. Wise Donald L. ; Gresser Joseph D. ; Trantolo Debra J. ; Hsu Yung-Yueh. Bioerodible polymeric semi-interpenetrating network alloys for surgical plates and bone cements, and method for making same. USP2000066071982.
  25. Vert Michel (Castelnau le Lez FRX) Coudane Jean (Montpellier FRX) Ustariz Christine (Montpellier FRX) Schwach Gregoire (Montpellier FRX). Bioresorbable-polymer microspheres of hydroxy acid polymer free from surfactant, their preparation and their application. USP1997095662938.
  26. Ng, Steven Y.; Heller, Jorge. Block copolymers based on poly(ortho esters) containing amine groups. USP2005096946145.
  27. Hair, Gregory A.; Boden, Scott D.. Bone mineralization proteins, DNA, vectors expression systems. USP2005026858431.
  28. Gregory A. Hair ; Scott D. Boden. Bone mineralization proteins, DNA, vectors, expression systems. USP2002096444803.
  29. Hair Gregory A. ; Boden Scott D.. Bone mineralization proteins, DNA, vectors, expression systems. USP2001106300127.
  30. Hair, Gregory A.; Boden, Scott D.. Bone mineralization proteins, DNA, vectors, expression systems. USP2003026521750.
  31. Gough Edward J.. Cell necrosis apparatus. USP2000066080150.
  32. Gough Edward J.. Cell necrosis apparatus. USP1999115980517.
  33. Gough Edward J.. Cell necrosis apparatus. USP2000106132425.
  34. McGregor, James; Watt, Paul W.. Coated bioabsorbable beads for wound treatment. USP2004036713083.
  35. Jon, Sangyong; Farokhazd, Omid C.; Langer, Robert S.; Cheng, Jianjun. Coated controlled release polymer particles as efficient oral delivery vehicles for biopharmaceuticals. USP2016119492400.
  36. Fertala, Andrzej; Ko, Frank. Collagen or collagen-like peptide containing polymeric matrices. USP2004066753311.
  37. Baird, Andrew; Gonzalez, Ana Maria; Logan, Ann; Berry, Martin. Compositions and methods for delivery of agents for neuronal regeneration and survival. USP2003046551618.
  38. Santamaria, Pedro; Moore, Anna. Compositions and methods for the prevention and treatment of autoimmune conditions. USP2013018354110.
  39. Santamaria, Pedro. Compositions and methods for the prevention and treatment of cancer. USP2016129511151.
  40. Santamaria, Pedro. Compositions and methods for the prevention and treatment of cancer. USP20190110172955.
  41. Kuo, Mei-chang; Lechuga-Ballesteros, David. Compositions comprising an active agent. USP2013088501240.
  42. Kuo,Mei chang; Lechuga Ballesteros,David. Compositions comprising an active agent. USP2009017482024.
  43. Thanoo Bagavathikanun Chithambara ; Murtagh James. Continuous microsphere process. USP1999085945126.
  44. Athanasiou Kyriacos A ; Boyan Barbara D. Continuous release polymeric implant carrier. USP2000016013853.
  45. Garver, Robert I.; Kalyanasundaram, Subramanian; Leong, Kam W.. Controlled release of bioactive substances. USP2005076916490.
  46. Sparks Randall T. (Gainesville GA) Geoghegan Edward J. (Athlone IEX). Controlled release powder and process for its preparation. USP1990074940588.
  47. Sparks Randall T. (Gainesville GA) Geoghegan Edward J. (Athlone IEX). Controlled release powder and process for its preparation. USP1990084952402.
  48. Labrie Fernand (Quebec CAX) Lepage Martin (Quebec CAX). Controlled release systems and low dose androgens. USP1997055629303.
  49. Labrie Fernand,CAX ; Lepage Martin,CAX. Controlled release systems and low dose androgens. USP1999015861387.
  50. Lenaerts, Vincent; Beck, Roland Herwig Friedrich; Van Bogaert, Elsie; Chouinard, Francois; Hopcke, Reiner; Desevaux, Cyril. Cross-linked high amylose starch for use in controlled-release pharmaceutical formulations and processes for its manufacture. USP2003086607748.
  51. Cheng, Jianjun; Davis, Mark E.; Khin, Kat T.. Cyclodextrin-based polymers for therapeutics delivery. USP2013118580242.
  52. Cheng, Jianjun; Davis, Mark E.; Khin, Kay T.. Cyclodextrin-based polymers for therapeutics delivery. USP2017019550860.
  53. Cheng, Jianjun; Davis, Mark E.; Khin, Kay T.. Cyclodextrin-based polymers for therapeutics delivery. USP2012118314230.
  54. Cheng, Jianjun; Davis, Mark E.; Khin, Kay T.. Cyclodextrin-based polymers for therapeutics delivery. USP2012088252276.
  55. Cheng, Jianjun; Davis, Mark E.; Khin, Kay T.. Cyclodextrin-based polymers for therapeutics delivery. USP2013038399431.
  56. Cheng, Jianjun; Davis, Mark E.; Khin, Kay T.. Cyclodextrin-based polymers for therapeutics delivery. USP2013038389499.
  57. Cheng, Jianjun; Davis, Mark E.; Khin, Kay T.. Cyclodextrin-based polymers for therapeutics delivery. USP2014038680202.
  58. Cheng, Jianjun; Davis, Mark E.; Khin, Kay T.. Cyclodextrin-based polymers for therapeutics delivery. USP2013088518388.
  59. Cheng, Jianjun; Davis, Mark E.; Khin, Kay T.. Cyclodextrin-based polymers for therapeutics delivery. USP2013128609081.
  60. Cheng, Jianjun; Davis, Mark E.; Khin, Kay T.. Cyclodextrin-based polymers for therapeutics delivery. USP2013118580243.
  61. Cheng, Jianjun; Davis, Mark E.; Khin, Kay T.. Cyclodextrin-based polymers for therapeutics delivery. USP2013118580244.
  62. Cheng, Jianjun; Davis, Mark E.; Khin, Kay T.. Cyclodextrin-based polymers for therapeutics delivery. USP2013128603454.
  63. Cheng, Jianjun; Davis, Mark E.; Khin, Kay T.. Cyclodextrin-based polymers for therapeutics delivery. USP2012028110179.
  64. Cheng, Jianjun; Davis, Mark; Khin, Kay T.. Cyclodextrin-based polymers for therapeutics delivery. USP2013078475781.
  65. Cheng, Jianjun; Davis, Mark; Khin, Kay T.. Cyclodextrin-based polymers for therapeutics delivery. USP2013038404662.
  66. Davis, Mark E.; Hwang, Jungyeon; Ke, Tianyi; Lim, Ching-Jou; Schluep, Thomas. Cyclodextrin-based polymers for therapeutics delivery. USP2013078497365.
  67. Brocchini,Stephen J.; Heller,Jorge; Tomlinson,Ryan; Duncan,Ruth; Garrett,Shane; Klee,Marcus M.. Degradable polyacetal polymers. USP2007057220414.
  68. Brown, Larry R.; Bisker-Leib, Vered; Scott, Terrence L.; Lafreniere, Debra; Machen, Jennifer; Giannoukakis, Nick. Delivery of AS-oligonucleotide microspheres to induce dendritic cell tolerance for the treatment of autoimmune type 1 diabetes. USP2015089115357.
  69. Brown, Larry R.; Bisker-Leib, Vered; Scott, Terrence L.; Lafreniere, Debra; Machen, Jennifer; Giannoukakls, Nick. Delivery of AS-oligonucleotide microspheres to induce dendritic cell tolerance for the treatment of autoimmune type 1 diabetes. USP2011027884085.
  70. Zawko, Scott; Schmidt, Christine. Dendritic macroporous hydrogels prepared by crystal templating. USP2018029896561.
  71. Zawko, Scott; Schmidt, Christine. Dendritic macroporous hydrogels prepared by crystal templating. USP2016049320827.
  72. Zawko, Scott; Schmidt, Christine. Dendritic macroporous hydrogels prepared by crystal templating. USP2014058728499.
  73. Zawko, Scott; Schmidt, Christine E.. Dendritic macroporous hydrogels prepared by crystal templating. USP2014038668863.
  74. Mason, David; Sambu, Shiva; Li, Chunhua; Chen, Yan. Dental appliance having ornamental design. USP20190210201409.
  75. Chen, Jennifer C.; Li, Chunhua; Morefield, Anthony. Dental appliance wear indication. USP2010127854609.
  76. Lillard, James W.; Singh, Rajesh; Singh, Shailesh. Detecting cancer with anti-CCL25 and anti-CCR9 antibodies. USP2014028658377.
  77. Dellamary,Luis A.; Tarara,Thomas E.; Kabalnov,Alexey; Weers,Jeffry G.; Schutt,Ernest G.. Dispersion for pulmonary delivery of a bioactive agent. USP2008077393544.
  78. Niitsu, Yoshiro; Yu, Lei; Liu, Jian; Zhao, Gang; Ma, Nianchun; Van, Sang. Drug carriers. USP2011088003621.
  79. Deluca Patrick P.. Drug delivery system involving interaction between protein or polypeptide and hydrophobic biodegradable polymer. USP2001106306406.
  80. Gibson John W. ; Holl Richard J. ; Tipton Arthur J.. Emulsion-based processes for making microparticles. USP2001096291013.
  81. John W. Gibson ; Richard J. Holl ; Arthur J. Tipton. Emulsion-based processes for making microparticles. USP2002086440493.
  82. Dunn,Richard L.. Emulsions for in-situ delivery systems. USP2006107128927.
  83. Farrar Graham Henry,GBX ; Tinsley-Bown Anne Margaret,GBX ; Jones David Hugh,CAX. Encapsulation of bioactive agents. USP2001106309569.
  84. Farrar, Graham Henry; Tinsley-Bown, Anne Margaret; Jones, David Hughes. Encapsulation of bioactive agents. USP2003056565777.
  85. Graham Henry Farrar GB; Anne Margaret Tinsley-Brown GB; David Hugh Jones CA. Encapsulation of bioactive agents. USP2002066406719.
  86. Tarara, Thomas E.; Weers, Jeffry G.; Kabalnov, Alexey; Schutt, Ernest G.; Dellamary, Luis A.. Engineered particles and methods of use. USP2012058168223.
  87. Tarara,Thomas E.; Weers,Jeffry G.; Kabalnov,Alexey; Schutt,Ernest G.; Dellamary,Luis A.. Engineered particles and methods of use. USP2007127306787.
  88. Robert E. Short ; Thomas B. Ottoboni. Excipient for the lyophilization of aqueous suspensions of microparticles. USP2002116482518.
  89. Yen Richard C. K.. Fibrinogen-coated microspheres. USP2001076264988.
  90. Richard C. K. Yen. Fibrinogen-coated particles for therapeutic use. USP2002056391343.
  91. Muller Walter (Neuwied DEX) Anders Edzard (Bornheim DEX). Floating system for oral therapy. USP1997055626876.
  92. Leonard, Edward F.; Reich, Ilan K.; Cortell, Stanley. Fluid separation devices, systems and methods. USP2013078496606.
  93. Tarara, Thomas E.; Weers, Jeffry G.; Eldon, Michael A.; Narashimhan, Rangachari; Clark, Andrew. Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use. USP2013038404217.
  94. Lipp, Michael W.; Batycky, Richard P.; Caponetti, Giovanni. Formulation for spray-drying large porous particles. USP2004066749835.
  95. Desai, Neil P.; Tao, Chunlin; Yang, Andrew; Louie, Leslie; Soon-Shiong, Patrick. Formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof. USP2012038137684.
  96. Bonadio Jeffrey ; Goldstein Steven A.. Gene transfer into bone cells and tissues. USP1998065763416.
  97. Thanoo, Bagavathikanun C.; Murtagh, James. Gonadotropin releasing hormone antagonists. USP2012128329863.
  98. Yasuharu Hakamatsuka JP; Hiroyuki Irie JP; Gen Horie JP. Hollow porous ceramic carrier for embedding in patient for sustained medicament release and method of preparation thereof. USP2002026350462.
  99. Kitagawa Naotaka. Hydrophilic polymeric material. USP2000046048908.
  100. Kitagawa Naotaka. Hydrophilic polymeric material and method of preparation. USP2001046218440.
  101. Iannacone, Matteo; Alexis, Frank; Basto, Pamela; Moseman, Elliott Ashley; Shi, Jinjun; Langer, Robert S.; Farokhzad, Omid C.; von Andrian, Ulrich; Tonti, Elena. Immunonanotherapeutics that provide IGG humoral response without T-cell antigen. USP2014128906381.
  102. Patel, Rajesh A.; Bucalo, Louis R.; Costantini, Lauren; Kleppner, Sofie. Implantable polymeric device for sustained release of dopamine agonist. USP2016039278163.
  103. Patel, Rajesh A.; Bucalo, Louis R.; Costantini, Lauren; Kleppner, Sofie. Implantable polymeric device for sustained release of dopamine agonist. USP2014108852623.
  104. Goldstein Steven A. ; Bonadio Jeffrey. In vivo gene transfer methods for wound healing. USP1999105962427.
  105. Bezwada Rao S. (Whitehouse Station NJ) Arnold Stephen C. (Franklin NJ) Shalaby Shalaby W. (Anderson SC) Williams Bernard L. (Martinsville NJ). Liquid absorbable copolymers for parenteral applications. USP1997055631015.
  106. Yewey Gerald L. ; Krinick Nancy L. ; Dunn Richard L. ; Radomsky Michael L. ; Brouwer Gerbrand ; Tipton Arthur J.. Liquid delivery compositions. USP1998065759563.
  107. Yewey Gerald L. ; Krinick Nancy L. ; Dunn Richard L. ; Radomsky Michael L. ; Brouwer Gerbrand ; Tipton Arthur J.. Liquid delivery compositions. USP1998075780044.
  108. Yewey Gerald L. ; Krinick Nancy L. ; Dunn Richard L. ; Radomsky Michael L. ; Brouwer Gerbrand ; Tipton Arthur J.. Liquid delivery compositions. USP1998045744153.
  109. Woiszwillo James E. ; Brown Larry R. ; Scott Terrence L. ; Di Jie ; Sudhalter Judith ; Blizzard Charles D.. Macromolecular microparticles and methods of production and use. USP2000076090925.
  110. Woiszwillo James E. ; Brown Larry R. ; Scott Terrence L. ; Di Jie ; Sudhalter Judith ; Blizzard Charles D. ; Riske Frank J.. Macromolecular microparticles and methods of production and use. USP1999115981719.
  111. Woiszwillo James E. ; Brown Larry R. ; Scott Terrence L. ; Di Jie ; Sudhalter Judith ; Blizzard Charles D. ; Riske Frank J.. Macromolecular microparticles and methods of production and use. USP2001076268053.
  112. Bernstein, Howard; Chickering, Donald; Khattak, Sarwat; Straub, Julie. Matrices formed of polymer and hydrophobic compounds for use in drug delivery. USP2004026689390.
  113. Bernstein, Howard; Chickering, Donald; Khattak, Sarwat; Straub, Julie. Matrices formed of polymer and hydrophobic compounds for use in drug delivery. USP2004056730322.
  114. Bernstein,Howard; Chickering,Donald; Khattak,Sarwat; Straub,Julie. Matrices formed of polymer and hydrophobic compounds for use in drug delivery. USP2007017160557.
  115. Bernstein,Howard; Chickering,Donald; Khattak,Sarwat; Straub,Julie. Matrices formed of polymer and hydrophobic compounds for use in drug delivery. USP2006057052719.
  116. Bagavathikanun Chithambara Thanoo ; James Murtagh. Method and apparatus for formulating microspheres and microcapsules. USP2002036361798.
  117. Thanoo Bagavathikanun Chithambara ; Murtagh James. Method and apparatus for formulating microspheres and microcapsules. USP2001086270802.
  118. Burke Paul A.. Method for fabricating polymer-based controlled-release devices. USP2001026183781.
  119. Burke Paul A.. Method for fabricating polymer-based controlled-release devices. USP1998105817343.
  120. Mathiowitz, Edith; Jong, Yong S.; Carino, Gerardo; Jacob, Jules S.. Method for gene therapy using nucleic acid loaded polymeric microparticles. USP2004016677313.
  121. Yen Richard C. K.. Method for making non-crosslinked protein particles for therapeutic and diagnostic use. USP1999085945033.
  122. Mathiowitz Edith (Brookline MA) Bernstein Howard (Cambridge MA) Morrel Eric (Needham MA) Schwaller Kirsten (Duxbury MA). Method for producing protein microspheres. USP1993125271961.
  123. Yi, Chin Feng; Gosiewska, Anna; Roweton, Susan. Method for promoting growth of tissue. USP2009107604817.
  124. Jones David Hugh,GBX ; Farrar Graham Henry,GBX ; Clegg James Christopher Stephen,GBX. Method of making microencapsulated DNA for vaccination and gene therapy. USP2001086270795.
  125. Jones, David Hugh; Farrar, Graham Henry; Clegg, James Christopher Stephen. Method of making microencapsulated DNA for vaccination and gene therapy. USP2004066743444.
  126. Xia, Younan; Im, Sang Hyuk; Jeong, Unyong. Method of making polymer hollow particles with controllable holes in their surfaces. USP2014048696955.
  127. Seo Young Jeong KR; Kuiwon Choi KR; Ick-Chan Kwon KR; Yong-Hee Kim KR; Jae Bong Choi KR; Kyu Back Lee KR. Method of manufacturing porous matrix-type controlled release systems using emulsion technique. USP2002096451348.
  128. Davis,Mark E.; Gonzalez,Hector; Hwang,Suzie (Sue Jean). Method of preparing a supramolecular complex containing a therapeutic agent and a multi-dimensional polymer network. USP2008057375096.
  129. Bonadio Jeffrey ; Goldstein Steven A.. Methods and compositions for multiple gene transfer into bone cells. USP1999085942496.
  130. Santamaria, Pedro. Methods and compositions for sustained immunotherapy. USP20181110124045.
  131. Santamaria, Pedro. Methods and compositions for treating multiple sclerosis and related disorders. USP20180910080808.
  132. Santamaria, Pedro. Methods and compositions for treating multiple sclerosis and related disorders. USP2017039603948.
  133. Tracy Mark A. ; Herberger John D. ; Burke Paul A. ; Herbert Paul F.. Methods for fabricating polymer-based controlled release devices. USP1999115989463.
  134. Brown, Larry; McGeehan, John K.; Rashba-Step, Julia; Scott, Terrence L.. Methods for fabrication, uses and compositions of small spherical particles prepared by controlled phase separation. USP2011128075919.
  135. Fu-Jya Tsai ; Brian T. Etzel. Methods for making a thermoplastic composition including polyethlene oxide and fibers including same. USP2002116479001.
  136. Mathiowitz, Edith; Thanos, Christopher; Liu, Zhi. Methods for micronization of hydrophobic drugs. USP2013098524829.
  137. Rutherford,Bruce; Somogyi,Christopher; White,Clinton; Rabins,Erick. Methods for treating dental conditions using tissue scaffolds. USP2007127309232.
  138. D'Souza,Martin J.; Oettinger,William Carl; Oliver,James Cameron. Methods of administering microencapsulated materials for immune modulated diseases. USP2006097105158.
  139. Leonard, Edward F.; West, Alan C.; Shapley, Nina C.; Tang, Zhongliang. Methods of blood-based therapies having a microfluidic membraneless exchange device. USP2011098021318.
  140. Darvari, Ramin; Lambert, Adam; Rashba-Step, Julia E.; Yang, Mark X.; Zhang, Junhong; O'Connell, Ed. Methods of processing compositions containing microparticles. USP2013028367427.
  141. Piran, Uri; Mehr, Eugene; Brown, Larry R.; McGeehan, John K.; O'Connell, Ed. Methods of processing compositions containing microparticles. USP2012128323685.
  142. Piran, Uri. Methods of processing multi-phasic dispersions. USP2012128323615.
  143. Tarara, Thomas E.; Weers, Jeffry G.; Kabalnov, Alexey; Schutt, Ernest G.; Dellamary, Luis A.. Methods of spray drying pharmaceutical compositions. USP2003056565885.
  144. Bonadio, Jeffrey; Yin, Wushan. Methods of using latent TGF-β binding proteins. USP2004086774105.
  145. Jones, David Hugh; Farrar, Graham Henry; Clegg, James Christopher Stephen. Microencapsulated DNA for vaccination and gene therapy. USP2003126667294.
  146. Mark A. Tracy ; Kevin L. Ward ; David S. Scher ; J. Keith Johnson. Microencapsulation and sustained release of biologically active acid-stable or free sulfhydryl-containing proteins. USP2002106465425.
  147. Burke Paul A.. Microencapsulation and sustained release of oligonucleotides. USP2001076265389.
  148. Burke, Paul A.. Microencapsulation and sustained release of oligonucleotides. USP2003046555525.
  149. Karnik, Rohit; Gu, Frank X.; Basto, Pamela; Cannizzaro, Chris; Khademhosseini, Alireza; Langer, Robert S.; Farokhzad, Omid C.. Microfluidic synthesis of organic nanoparticles. USP2016079381477.
  150. Hedley Mary Lynne ; Curley Joanne M. ; Langer Robert S.. Microparticles for delivery of nucleic acid. USP1998075783567.
  151. Brown, Larry R.; Giannoukakis, Nick; Gillis, Kimberly A.; Trucco, Massimo. Microsphere-based composition for preventing and/or reversing new-onset autoimmune diabetes. USP2013038389493.
  152. Spenlehauer Gilles,FRX ; Veillard Michel,FRX ; Verrechia Thierry,FRX. Microspheres, process for their preparation and their use. USP2000096120805.
  153. Rasschaert, Kristien; Goddeeris, Bruno; Cox, Eric; Deforce, Dieter. Mucosal membrane receptor and uses thereof. USP2017059636417.
  154. Rasschaert, Kristien; Goddeeris, Bruno; Cox, Eric; Deforce, Dieter. Mucosal membrane receptor and uses thereof. USP2015069052317.
  155. Chandrashekhar P. Pathak ; Shikha P. Barman ; C. Michael Philbrook ; Amarpreet S. Sawhney ; Arthur J. Coury ; Luis Z. Avila ; Mark T. Kieras. Multiblock biodegradable hydrogels for drug delivery and tissue treatment. USP2002066410645.
  156. Pathak Chandrashekhar P. ; Barman Shikha P. ; Philbrook C. Michael ; Sawhney Amarpreet S. ; Coury Arthur J. ; Avila Luis Z. ; Kieras Mark T.. Multiblock biodegradable hydrogels for drug delivery and tissue treatment. USP2001036201065.
  157. Pathak, Chandrashekhar P.; Barman, Shikha P.; Philbrook, C. Michael; Sawhney, Amarpreet S.; Coury, Arthur J.; Avila, Luis Z.; Kieras, Mark T.. Multiblock biodegradable hydrogels for drug delivery and tissue treatment. USP2003106639014.
  158. Pathak, Chandrashekhar P.; Barman, Shikha P.; Philbrook, C. Michael; Sawhney, Amarpreet S.; Coury, Arthur J.; Avila, Luis Z.; Kieras, Mark T.. Multiblock biodegradable hydrogels for drug delivery and tissue treatment. USP2005086923986.
  159. Gough Edward J. ; Stein Alan A.. Multiple antenna ablation apparatus and method. USP1999095951547.
  160. Gough Edward J. ; Stein Alan A.. Multiple antenna ablation apparatus and method. USP1999075925042.
  161. Gough Edward J. ; Stein Alan A.. Multiple antenna ablation apparatus and method. USP1999065913855.
  162. Gough, Edward J.; Stein, Alan A.; Edwards, Stuart D.. Multiple antenna ablation apparatus and method. USP2005106958062.
  163. Gough Edward J. ; Stein Alan A.. Multiple antenna ablation apparatus and method with cooling element. USP2000056059780.
  164. Edwards Stuart D. ; Lax Ronald G. ; Sharkey Hugh. Multiple electrode ablation apparatus. USP2000066071280.
  165. Zepeda John ; Hirsch Chaya ; Lee Kee ; Gough Edward J.. Multiple electrode ablation apparatus and method. USP2000076090105.
  166. Iannacone, Matteo; von Andrian, Ulrich; Farokhzad, Omid C.; Alexis, Frank; Basto, Pamela; Shi, Jinjun; Moseman, Elliott Ashley; Langer, Robert S.; Tonti, Elena. Nicotine immunonanotherapeutics. USP2015018932595.
  167. Yen Richard C. K.. Non-crosslinked protein particles for therapeutic and diagnostic use. USP1998035725804.
  168. Yen Richard C. K. (Glendora CA). Non-crosslinked protein particles for therapeutic and diagnostic use. USP1997045616311.
  169. Brown, Larry R.; Scott, Terrence L.; Lafreniere, Debra; Bisker-Leib, Vered. Nucleic acid microspheres, production and delivery thereof. USP2010107815941.
  170. Scott, Terrence; Lafreniere, Debra; Bisker-Leib, Vered; Brown, Larry. Nucleic acid microspheres, production and delivery thereof. USP2016059339465.
  171. Mayes, Sarah; Schmidt, Christine E.. One-step processing of hydrogels for mechanically robust and chemically desired features. USP2015028946194.
  172. Moretti, Matteo G.; Freed, Lisa E.; Langer, Robert S.. Oscillating cell culture bioreactor. USP2015129217129.
  173. Ma, Peter X.; Wei, Guobao. Particle-containing complex porous materials. USP2012098268344.
  174. Ma, Peter X.; Wei, Guobao. Particle-containing complex porous materials. USP2013108568769.
  175. Basu,Sujit K.; Hrkach,Jeffrey; Lipp,Michael; Elbert,Katharina; Edwards,David A.. Particles for inhalation having sustained release properties. USP2006057048908.
  176. Edwards, David A.; Hrkach, Jeffrey S.. Particles for inhalation having sustained release properties. USP2010037678364.
  177. Edwards, David A.; Langer, Robert S.; Vanbever, Rita; Mintzes, Jeffrey; Wang, Jue; Chen, Donghao. Particles for inhalation having sustained release properties. USP2009127628977.
  178. Vanbever,Rita; Langer,Robert S.; Edwards,David A.; Mintzes,Jeffrey; Wang,Jue; Chen,Donghao. Particles for inhalation having sustained release properties. USP2006057052678.
  179. Hanes Justin ; Edwards David A. ; Evora Carmen,ESX ; Langer Robert. Particles incorporating surfactants for pulmonary drug delivery. USP200102RE37053.
  180. Hanes Justin ; Edwards David A. ; Evora Carmen,ESX ; Langer Robert. Particles incorporating surfactants for pulmonary drug delivery. USP1999015855913.
  181. Batycky,Richard P.; Edwards,David A.; Lipp,Michael M.. Particulate compositions for pulmonary delivery. USP2007027182961.
  182. Batycky,Richard P.; Edwards,David A.; Lipp,Michael M.. Particulate compositions for pulmonary delivery. USP2008067384649.
  183. Ron Eyal (Lexington MA) Turek Thomas J. (Boston MA) Isaacs Benjamin S. (Tewksbury MA) Patel Himakshi (Tewksbury MA) Kenley Richard A. (Andover MA). Pharmaceutical formulations of osteogenic proteins. USP1997015597897.
  184. Kasica James J. ; Thomas David J. ; Zallie James P.. Pharmaceutical products containing thermally-inhibited starches. USP1998115830884.
  185. Weers, Jeffry G.; Tarara, Thomas E.; Dellamary, Luis A.; Riess, Jean G.; Schutt, Ernest G.. Phospholipid-based powders for drug delivery. USP2014048709484.
  186. Weers, Jeffry G; Tarara, Thomas E; Dellamary, Luis A; Riess, Jean G; Schutt, Ernest G. Phospholipid-based powders for drug delivery. USP2016099439862.
  187. Weers,Jeffry G.; Tarara,Thomas E.; Dellamary,Luis A.; Riess,Jean G.; Schutt,Ernest G.. Phospholipid-based powders for drug delivery. USP2008107442388.
  188. Tsai Fu-Jya ; Etzel Brian T.. Polyethylene oxide thermoplastic composition. USP2000016010971.
  189. Davis, Mark E.; Hwang, Jungyeon; Ke, Tianyi; Lim, Ching-jou; Schluep, Thomas. Polymer drug conjugates with tether groups for controlled drug delivery. USP2017049610360.
  190. Southard Jeffrey L. ; Dunn Richard L.. Polymer formulation for prevention of surgical adhesions. USP1999105962006.
  191. Li Nai-Hong,CAX ; Benson James R. ; Kitagawa Naotaka. Polymeric microbeads and methods of preparation. USP2000086100306.
  192. Mao, Hai-Quan; Lin, Kevin Y.; Hendriks, Bart S.; Leong, Kam W.; Haller, Michael F.. Polymers for delivery of nucleic acids. USP2003046548302.
  193. Cooper,Andrew Ian; Zhang,Haifei. Porous beads and method of production thereof. USP2006127153572.
  194. Straub, Julie; Altreuter, David; Bernstein, Howard; Chickering, III, Donald E.; Khattak, Sarwat; Randall, Greg. Porous drug matrices and methods of manufacture thereof. USP2014098821938.
  195. Straub, Julie; Bernstein, Howard; Chichering, III, Donald E.; Khattak, Sarwat; Randall, Greg. Porous drug matrices and methods of manufacture thereof. USP2005086932983.
  196. Straub,Julie A.; Bernstein,Howard; Chickering, III,Donald E.; Khattak,Sarwat; Randall,Greg. Porous paclitaxel matrices and methods of manufacture thereof. USP200809RE40493.
  197. David A. Edwards ; Giovanni Caponetti ; Jeffrey S. Hrkach ; Noah Lotan IL; Justin Hanes ; Robert S. Langer ; Abdellaziz Ben-Jebria. Porous particles comprising excipients for deep lung delivery. USP2002086436443.
  198. Edwards, David A.; Caponetti, Giovanni; Hrkach, Jeffrey S.; Lotan, Noah; Hanes, Justin; Langer, Robert S.; Ben-Jebria, Abdellaziz. Porous particles comprising excipients for deep lung delivery. USP2004056740310.
  199. Edwards,David A.; Caponetti,Giovanni; Hrkach,Jeffrey S.; Lotan,Noah; Hanes,Justin; Langer,Robert S.; Ben Jebria,Abdellaziz. Porous particles comprising excipients for deep lung delivery. USP2008107435408.
  200. David A. Edwards ; Giovanni Caponetti ; Jeffrey S. Hrkach ; Noah Lotan IL; Justin Hanes ; Robert S. Langer ; Abdellaziz Ben-Jebria. Porous particles for deep lung delivery. USP2002096447753.
  201. Edwards, David A.; Langer, Robert S.; Vanbever, Rita; Mintzes, Jeffrey; Wang, Jue; Chen, Donghao. Preparation of novel particles for inhalation. USP2003116652837.
  202. Edwards David A. ; Langer Robert S. ; Vanbever Rita ; Mintzes Jeffrey ; Wang Jue ; Chen Donghao. Preparation of particles for inhalation. USP1999115985309.
  203. Mathiowitz, Edith; Chickering, III, Donald; Jong, Yong S.; Jacob, Jules S.. Process for preparing microparticles through phase inversion phenomena. USP2003096616869.
  204. Brown,Larry R.. Production of microspheres. USP2008057374782.
  205. Bernstein Howard (Cambridge MA) Morrel Eric (Needham MA) Mathiowitz Edith (Brookline MA) Schwaller Kirsten (Duxbury MA) Beck Thomas R. (Concord MA). Protein microspheres and methods of using them. USP1997105679377.
  206. Brown, Larry; Bisker-Leib, Vered; LaFreniere, Debra; McGeehan, John; Rashba-Step, Julia; Scott, Terrence. Protein microspheres having injectable properties at high concentrations. USP2012128333995.
  207. Brown, Larry R.; Yang, Mark X.; O'Connell, Ed. Protein microspheres retaining pharmacokinetic and pharmacodynamic properties. USP2014058728525.
  208. Tarara, Thomas E.; Weers, Jeffry G.; Venthoye, Geraldine. Pulmonary delivery of aminoglycoside. USP2014058715623.
  209. Tarara, Thomas E; Weers, Jeffry G; Venthoye, Maria Geraldine. Pulmonary delivery of aminoglycoside. USP2016089421166.
  210. Tarara,Thomas E.; Weers,Jeffry G.; Venthoye,Geraldine. Pulmonary delivery of aminoglycosides. USP2008057368102.
  211. Tarara, Thomas E.; Weers, Jeffrey G.; Kabalnov, Alexey; Schutt, Ernest G.; Dellamary, Luis A.. Pulmonary delivery particles comprising an active agent. USP2017019554993.
  212. Bonadio Jeffrey ; Yin Wushan. Recombinant production of latent TGF-beta binding protein-3 (LTBP-3). USP2000066074840.
  213. Chen, Jennifer C.; Su, Li-Hung; Li, Chunhua. Release agent receptacle. USP2014128899976.
  214. Chen, Jennifer C.; Su, Li-Hung; Li, Chunhua. Release agent receptacle. USP2017089730769.
  215. Chen, Jennifer C.; Su, Li-Hung; Li, Chunhua. Release agent receptacle. USP20181210154889.
  216. Weers, Jeffry G.; Schutt, Ernest G.; Dellamary, Luis A.; Tarara, Thomas E.; Kabalnov, Alexey. Respiratory dispersion for metered dose inhalers comprising perforated microstructures. USP2012088246934.
  217. Tombran Tink,Joyce; Chader,Gerald J.; Becerra,Sofia Patricia; Rodriguez,Ignacio R.; Steele,Fintan R.; Johnson,Lincoln V.. Retinal pigmented epithelium derived neurotrophic factor. USP2009037511009.
  218. Joyce Tombran-Tink ; Gerald J. Chader ; Sofia Patricia Becerra ; Ignacio R. Rodriguez ; Fintan R. Steele ; Lincoln V. Johnson. Retinal pigmented epithelium derived neurotrophic factor and methods of use. USP2002096451763.
  219. Roser, Bruce J.; Kampinga, Jaap; Colaco, Camilo; Blair, Julian. Solid dose delivery vehicle and methods of making same. USP2010067744925.
  220. Roser, Bruce J.; Kampinga, Jaap; Colaco, Camilo; Blair, Julian. Solid dose delivery vehicle and methods of making same. USP2010087785631.
  221. Roser, Bruce J.; Kampinga, Jaap; Colaco, Camilo; Blair, Julian. Solid dose delivery vehicle and methods of making same. USP2010087780991.
  222. Dellamary,Luis A.; Tarara,Thomas; Kabalnov,Alexey; Weers,Jeffry; Schutt,Ernest. Stabilized bioactive preparations and method of use. USP2007047205343.
  223. Luis A. Dellamary ; Thomas E. Tarara ; Alexey Kabalnov ; Jeffry G. Weers ; Ernest G. Schutt. Stabilized bioactive preparations and methods of use. USP2002086433040.
  224. Weers, Jeffry G.; Schutt, Ernest G.; Dellamary, Luis A.; Tarara, Thomas E.; Kabalnov, Alexey. Stabilized preparation for use in metered dose inhalers. USP2003106638495.
  225. Weers Jeffry G. ; Schutt Ernest G. ; Dellamary Luis A. ; Tarara Thomas E. ; Kabalnov Alexey. Stabilized preparations for use in metered dose inhalers. USP2001106309623.
  226. Weers, Jeffry G.; Schutt, Ernest G.; Dellamary, Luis; Tarara, Thomas E.; Kabalnov, Alexey. Stabilized preparations for use in metered dose inhalers. USP2009127628978.
  227. Schutt, Ernest G.; Tarara, Thomas E.; Dellamary, Luis A.; Kabalnov, Alexey; Weers, Jeffry G.. Stabilized preparations for use in nebulizers. USP2005096946117.
  228. Foster Linda C. ; Kuo Mei-chang ; Billingsley Sheila R.. Stable glassy state powder formulations. USP2001076258341.
  229. Foster Linda C. ; Kuo Mei-chang ; Billingsley Shelia R.. Stable glassy state powder formulations. USP2001106309671.
  230. Foster, Linda C.; Kuo, Mei-chang; Billingsley, Shelia R.. Stable glassy state powder formulations. USP2003076589560.
  231. Dellamary, Luis A.; Reiss, Jean; Schutt, Ernest G.; Weers, Jeffry G.; Tarara, Thomas E.. Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery. USP2014118877162.
  232. Dellamary, Luis A.; Riess, Jean; Schutt, Ernest G.; Weers, Jeffry G.; Tarara, Thomas E.. Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use. USP2011017871598.
  233. Dellamary, Luis A; Riess, Jean; Schutt, Ernest G; Weers, Jeffry G; Tarara, Thomas E. Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use. USP2013018349294.
  234. Edwards, David A.; Hrkach, Jeffrey S.. Stable spray-dried protein formulations. USP2005106956021.
  235. Farokhzad, Omid C.; Radovic-Moreno, Aleksandar Filip; Langer, Robert S.. System for screening particles. USP2016029267937.
  236. Cheng, Jianjun; Farokhzad, Omid C.; Langer, Robert S.; Teply, Benjamin A.; Zale, Stephen E.. System for targeted delivery of therapeutic agents. USP2014088802153.
  237. Abolfathi, Amir; Chen, Jennifer C.; Li, Chunhua; Tricca, Robert E.; Wu, Benjamin M.. Systems and methods for dental appliance compliance indication. USP2010117824180.
  238. Abolfathi, Amir; Chen, Jennifer C.; Li, Chunhua; Tricca, Robert E.; Wu, Benjamin M.. Systems and methods for dental appliance compliance indication. USP2009067553157.
  239. Leonard, Edward F.; West, Alan C.; Shapley, Nina C.; Tang, Zhongliang. Systems and methods for membraneless dialysis. USP2013078491516.
  240. Leonard, Edward F.; West, Alan C.; Shaplely, Nina C.; Tang, Zhongliang. Systems and methods of blood-based therapies having a microfluidic membraneless exchange device. USP2009097588550.
  241. Leonard, Edward F.; West, Alan C.; Shapley, Nina C.; Tang, Zhongliang. Systems and methods of blood-based therapies having a microfluidic membraneless exchange device. USP2010127850633.
  242. Leonard, Edward F.; West, Alan C.; Aucoin, Christian P.; Nanne, Edgar E.. Systems and methods of microfluidic membraneless exchange using filtration of extraction outlet streams. USP2010067727399.
  243. Leonard, Edward F.; West, Alan C.; Aucoin, Christian Paul; Nanne, Edgar E.. Systems and methods of microfluidic membraneless exchange using filtration of extraction outlet streams. USP2012098257593.
  244. Leonard, Edward F.; West, Alan C.; Aucoin, Christian Paul; Nanne, Edgar E.. Systems and methods of microfluidic membraneless exchange using filtration of extraction outlet streams. USP2013068470180.
  245. Leonard, Edward F.; West, Alan C.; Aucoin, Christian Paul; Nanne, Edgar E.. Systems and methods of microfluidic membraneless exchange using filtration of extraction outlet streams. USP2012018097162.
  246. Leonard, Edward F.; West, Alan C.; Aucoin, Christian Paul; Nanne, Edgar E.. Systems and methods of microfluidic membraneless exchange using filtration of extraction outlet streams. USP2012018092684.
  247. Leonard, Edward F.; West, Alan C.; Aucoin, Christian Paul; Nanne, Edgar E.. Systems and methods of microfluidic membraneless exchange using filtration of extraction outlet streams. USP2012018097153.
  248. Tsai Fu-Jya ; Etzel Brian T.. Thermoplastic composition including polyethylene oxide. USP2000086110849.
  249. Gough Edward J. ; Stein Alan A.. Tumor ablation apparatus. USP1999075928229.
  250. von Andrian, Ulrich H.; Farokhzad, Omid C.; Langer, Robert S.; Junt, Tobias; Moseman, Elliott Ashley; Zhang, Liangfang; Basto, Pamela; Iannacone, Matteo; Alexis, Frank. Vaccine nanotechnology. USP2016109474717.
  251. von Andrian, Ulrich H.; Farokhzad, Omid C.; Langer, Robert S.; Junt, Tobias; Moseman, Elliott Ashley; Zhang, Liangfang; Basto, Pamela; Iannacone, Matteo; Alexis, Frank. Vaccine nanotechnology. USP2016129526702.
  252. von Andrian, Ulrich H.; Farokhzad, Omid C.; Langer, Robert S.; Junt, Tobias; Moseman, Elliott Ashley; Zhang, Liangfang; Basto, Pamela; Iannacone, Matteo; Alexis, Frank. Vaccine nanotechnology. USP2017019539210.
  253. Gombotz Wayne R. (Lexington MA) Healy Michael S. (E. Bridgewater MA) Brown Larry R. (Newton MA). Very low temperature casting of controlled release microspheres. USP1991055019400.

IPC 상위 출원인