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Controlled release drug delivery systems comprised of spherical microporous polymeric network of interconnecting channels containing pore incorporated drugs or other agents wherein the drugs or agents are confined within the pore channel are described. Also disclosed are processing parameters in con

Controlled release drug delivery systems comprised of spherical microporous polymeric network of interconnecting channels containing pore incorporated drugs or other agents wherein the drugs or agents are confined within the pore channel are described. Also disclosed are processing parameters in connection with the novel method of the invention for obtaining drug delivery systems especially suited for parenteral as well as oral administration.

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A method for preparing a relatively homogenous essentially spherical microporous polymeric network of interconnecting channels containing a pore incorporated agent confined essentially completely inside the channels comprising preparing an agentpolymer-solvent dispersed first phase, dispersing said

A method for preparing a relatively homogenous essentially spherical microporous polymeric network of interconnecting channels containing a pore incorporated agent confined essentially completely inside the channels comprising preparing an agentpolymer-solvent dispersed first phase, dispersing said first phase in a continuous solvent second phase to obtain a suspension, removing solvent from said suspension by freeze drying, or dilution-extraction-precipitation and recovering said microporous polymeric network. A drug delivery system comprising a spherical microporous polymeric network of interconnecting channels containing a drug wherein said drug is distributed essentially within the channels of said microporous polymeric network. The drug delivery system according to claim 15 or 16 wherein said polymer comprises a polyester polymer of polyglycolic acid or polylactic acid or a co-polymer of glycolide and L(-)lactide.