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특허 상세정보

MyON담기
내보내기 페이스북 공유 카카오톡 공유

Vaginal ring

특허상세정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판) A61M-007/00   
미국특허분류(USC) 424/432 ; 604/8911 ; 424/430
출원번호 US-0014316 (1987-02-13)
우선권정보 DE-3040978 (1980-10-28)
발명자 / 주소
  • Zimmermann Ingfried (Berlin DEX) Windt Fred (Berlin DEX) Reck Hans-Jrgen (Berlin DEX)
출원인 / 주소
  • Schering Aktiengesellschaft (Berlin and Bergkamen DEX 03)
인용정보 피인용 횟수 : 49  인용 특허 : 4
초록
▼

A vaginal ring comprises a supporting ring 1 free of active agent. A layer 2, which contains an active agent such as a steroid, is applied on its outer rim, optionally in a continuous groove provided in the supporting ring. This layer, in turn, is coated with a layer 3 devoid of active ingredient. All components preferably comprise an LTV silicone elastomer. The ratio of the thickness of the layer 2, containing an active agent, to the layer 3, free of active agent, is about 5-50:1. As a result, a long-term and uniform release rate is achieved for the act...

대표
청구항
▼

A vaginal ring spaced from an axis of revolution, the ring having an inside diameter and an outside diameter, a radial thickness with respect to the axis and an axial thickness in the direction of the axis, the ring having first and second exposed radial surfaces and the ring further comprising: a supporting ring made of a pharmacologically acceptable material and being essentially free of medicament; the supporting ring having a first annular surface between inner and outer circumferential peripheries extending in a radial direction and generally facing...

인용문헌 (4)

  1. Schopflin Gisela (Berlin DT), Drug excipient of silicone rubber.
  2. Nash Harold A. (Harrington Park NJ) Mishell ; Jr. Daniel R. (Palos Verdes Estates CA), Intravaginal ring.
  3. Schopflin Gisela (Berlin DEX) Laudahn Gerhard (Berlin DEX) Muhe Barbara (Berlin DEX) Hartmann Heidemarie (Berlin DEX) Windt Fred (Berlin DEX), Vaginal ring.
  4. Schopflin Gisela (Berlin DT) Laudahn Gerhard (Berlin DT) Muhe Barbara (Berlin DT) Hartmann Heidemarie (Berlin DT) Windt Fred (Berlin DT), Vaginal ring.

이 특허를 인용한 특허 (49)

  1. Alster, Yair; de Juan, Jr., Eugene; Reich, Cary J.; Boyd, Stephen; Sierra, David; Alejandro, Jose D.; Macfarlane, K. Angela; Sutton, Douglas, Anterior segment drug delivery.
  2. Alster, Yair; de Juan, Jr., Eugene; Reich, Cary J.; Boyd, Stephen; Sierra, David; Alejandro, Jose D.; Macfarlane, K. Angela; Sutton, Douglas, Anterior segment drug delivery.
  3. Contente Audrey ; Guthrie Wendell W. ; Wills Randy S., Apparatus for manufacturing elastomeric articles.
  4. Anderson David W. ; Buuck Robert E. ; Thornton Arnold W. ; Zhang Xiao Kang, Channeled vaginal insert and method for treating urogenital disorders.
  5. Berg, Eric P.; Stella, Rita, Coating with antimicrobial agents.
  6. Berg, Eric P.; Stella, Rita, Coating with antimicrobial agents.
  7. Devlin, Brid; Holt, Jonathon Daryll; Brimer, Andrew Nathan; Nuttall, Jeremy Peter; Malcolm, Karl; Fetherston, Susan Margaret; Boyd, Peter John James, Combination therapy intravaginal rings.
  8. Anderson David W. ; Buuck Robert E. ; Thornton Arnold W. ; Zhang Xiao Kang, Compressible vaginal insert and method for treating urogenital disorders.
  9. Prescott,James H.; Kreiger,Timothy; Proos,Elizabeth R., Control of drug release by transient modification of local microenvironments.
  10. Smith, Molly K.; Arehart, Kelly D.; Huang, Lei; Yang, Shu-Ping; Huang, Yanbin, Degradable therapeutic delivery device.
  11. Smith, Molly K.; Arehart, Kelly D.; Huang, Lei; Yang, Shu-Ping; Huang, Yanbin, Degradable therapeutic delivery device.
  12. Ausiello, Dennis; Santini, Jr., John T.; Herman, Stephen J.; Prescott, James H.; Uhland, Scott A.; Maloney, John M.; Polito, Benjamin F., Implantable device for controlled, extended delivery of parathyroid hormone.
  13. Nabahi Shohre,GB2, Intravaginal drug delivery device.
  14. Contente Audrey, Intravaginal drug delivery system and discharge collection device.
  15. Saleh Saleh Ismail,EGX ; Nash Harold A. ; Bardin C. Wayne ; Harmon Troy, Intravaginal rings with insertable drug-containing core.
  16. Saleh Saleh Ismail,EGX ; Nash Harold A. ; Bardin C. Wayne ; Harmon Troy, Intravaginal rings with insertable drug-containing core.
  17. Ausiello,Dennis; Santini, Jr.,John T.; Herman,Stephen J.; Prescott,James H.; Uhland,Scott A.; Maloney,John M.; Polito,Benjamin F., Method and device for the controlled delivery of parathyroid hormone.
  18. Michelle McKenna ; Angela Reid-Haqq ; John F. Cline ; Edward J. Gabrielski, Method for injection molding manufacture of controlled release devices.
  19. Ron, Eyal S.; Langer, Robert S.; Crowley, Jr., William F., Methods and devices for the sustained release of multiple drugs.
  20. Ron, Eyal S.; Langer, Robert S.; Crowley, Jr., William F., Methods and devices for the sustained release of multiple drugs.
  21. Ron, Eyal S.; Langer, Robert S.; Crowley, Jr., William F., Methods and devices for the sustained release of multiple drugs.
  22. Ron, Eyal S.; Langer, Robert S.; Crowley, Jr., William F., Methods and devices for the sustained release of multiple drugs.
  23. DiLiberti, Charles E.; Mahashabde, Anu, Methods of reducing symptoms in subjects using single dosage forms with tapering release rates.
  24. Ahmed, Salah U.; Tsao, Jiaxiang; Mahashabde, Anu; Harrison, Diane D., Monolithic intravaginal rings comprising progesterone and methods of making and uses thereof.
  25. Variano, Bruce; Speck, Jeffrey; Sallent, Maria Teresa; Evans, Simone, Multi-layered gradient vaginal ring.
  26. Bernick, Brian A.; Cacace, Janice Louise; Persicaner, Peter H. R.; Irani, Neda; Amadio, Julia M., Natural combination hormone replacement formulations and therapies.
  27. Bernick, Brian A.; Cacace, Janice Louise; Persicaner, Peter H. R.; Irani, Neda; Amadio, Julia M., Natural combination hormone replacement formulations and therapies.
  28. Bernick, Brian A.; Cacace, Janice Louise; Persicaner, Peter H. R.; Irani, Neda; Amadio, Julia M., Natural combination hormone replacement formulations and therapies.
  29. Bernick, Brian A.; Cacace, Janice Louise; Persicaner, Peter H. R.; Irani, Neda; Amadio, Julia M., Natural combination hormone replacement formulations and therapies.
  30. Bernick, Brian A.; Cacace, Janice Louise; Persicaner, Peter H. R.; Irani, Neda; Amadio, Julia M., Natural combination hormone replacement formulations and therapies.
  31. Bernick, Brian A.; Cacace, Janice Louise; Persicaner, Peter H. R.; Irani, Neda; Amadio, Julia M., Natural combination hormone replacement formulations and therapies.
  32. Bernick, Brian A.; Cacace, Janice Louise; Persicaner, Peter H. R.; Irani, Neda; Amadio, Julia M., Natural combination hormone replacement formulations and therapies.
  33. Bernick, Brian A.; Cacace, Janice Louise; Persicaner, Peter H. R.; Irani, Neda; Amadio, Julia M., Natural combination hormone replacement formulations and therapies.
  34. Bernick, Brian A.; Cacace, Janice Louise; Persicaner, Peter H. R.; Irani, Neda; Amadio, Julia M., Natural combination hormone replacement formulations and therapies.
  35. Bernick, Brian A.; Persicaner, Peter H. R.; Amadio, Julia M., Natural combination hormone replacement formulations and therapies.
  36. Saxena, Brij; Singh, Mukul; Lerner, Sidney, Non-hormonal vaginal contraceptive.
  37. de Juan, Jr., Eugene; Alster, Yair; Reich, Cary J.; MacFarlane, K. Angela; Chang, Janelle; Boyd, Stephen; Sierra, David; Alejandro, Jose D.; Sutton, Douglas; Gould, Alexander J., Ocular insert apparatus and methods.
  38. de Juan, Jr., Eugene; Alster, Yair; Reich, Cary J.; Macfarlane, K. Angela; Chang, Janelle; Boyd, Stephen; Sierra, David; Alejandro, Jose D.; Sutton, Douglas; Gould, Alexander J., Ocular insert apparatus and methods.
  39. Rubin, Anne Brody; Alster, Yair; Reich, Cary J., Ophthalmic system for sustained release of drug to eye.
  40. Malcolm, Karl; Woolfson, David; Romano, Joseph, Platinum-catalyzed intravaginal rings.
  41. Malcolm, Karl; Woolfson, David; Romano, Joseph, Platinum-catalyzed intravaginal rings.
  42. Bernick, Brian A.; Amadio, Julia M.; Persicaner, Peter H. R.; Cacace, Janice Louise; Thorsteinsson, Thorsteinn; Sancilio, Frederick D., Progesterone formulations.
  43. Bernick, Brian A.; Amadio, Julia M.; Persicaner, Peter H. R.; Irani, Neda; Cacace, Janice Louise; Thorsteinsson, Thorsteinn; Sancilio, Frederick D., Soluble estradiol capsule for vaginal insertion.
  44. Shadiack, Annette; Persicaner, Peter H. R.; Inskeep, Philip B.; Thorsteinsson, Thorsteinn; Sancilio, Frederick D.; Legassie, Jason D., Steroid hormone pharmaceutical composition.
  45. Bernick, Brian A.; Amadio, Julia M.; Persicaner, Peter H. R.; Cacace, Janice Louise; Irani, Neda; Sancilio, Frederick D., Transdermal hormone replacement therapies.
  46. Contente, Audrey; Ross, Bruce F.; Potter, Richard C., Vaginal discharge collection device and intravaginal drug delivery system.
  47. Anderson David W. ; Buuck Robert E. ; Thornton Arnold W. ; Zhang Xiao Kang, Vaginal insert and method for treating urogenital disorders.
  48. Bernick, Brian A.; Amadio, Julia M., Vaginal inserted estradiol pharmaceutical compositions and methods.
  49. Mirkin, Sebastian; Amadio, Julia M.; Bernick, Brian A., Vaginal inserted estradiol pharmaceutical compositions and methods.

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