$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

Controlled release combination of carbidopa/levodopa 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-009/20
  • A61K-009/22
  • A61K-009/26
출원번호 US-0223861 (1988-07-25)
발명자 / 주소
  • Dempski Robert E. (Dresher PA) Scholtz Edward C. (King of Prussia PA) Nibbelink Donald W. (Lansdale PA) Reines Scott A. (New Hope PA)
출원인 / 주소
  • Merck & Co., Inc. (Rahway NJ 02)
인용정보 피인용 횟수 : 32  인용 특허 : 18

초록 ▼

A matrix or monolithic drug delivery system for the controlled release of carbidopa and levodopa consists of the two drugs uniformly dispersed in a polymer vehicle at a concentration that is greater than the solubility of either drug in the polymer. Treatment of parkinsonism with the controlled rele

대표청구항 ▼

A controlled release oral dosage formulation comprising a uniform dispersion of 25-100 mg of carbidopa, 100-400 mg of levodopa, 1-10 mg of a tablet lubricant and in mixture thereof with a pharmaceutically acceptable dye, in a polymer vehicle comprising 5-25 mg of water-soluble hydroxypropyl cellulos

이 특허에 인용된 특허 (18)

  1. Bagli Jehan F. (Kirkland CAX) Bgri Tibor (Montreal CAX) Voith Katherine (Dorval CAX), 2-(1-Piperazinyl)-2,4,6-cycloheptatrien-1-one derivatives.
    상세보기
  2. Bagli Jehan F. (Kirkland CAX) Bgri Tibor (Montreal CAX) Voith Katherine (Dorval CAX), 2-(4-Hydroxyalkyl-1-piperazinyl)-2,4,6-cycloheptatrien-1-one derivatives.
    상세보기
  3. Bagli Jehan F. (Kirkland CAX) Bgri Tibor (Montreal CAX) Voith Katherine (Dorval CAX), 2-(4-Substituted alkyl-1-piperazinyl)-2,4,6-cycloheptatrien-1-one derivatives.
    상세보기
  4. Fix Joseph A. (Lawrence KS) Pogany Stefano A. (Lawrence KS), a 상세보기
  • Narabayashi Hirotaro (5-12-8 Nakameguro ; Meguro-ku ; Tokyo-to JPX) Kondo Tomoyoshi (2-12-3 Sugamo ; Toshima-ku ; Tokyo-to JPX) Hayashi Akira (9-5 ; Tsukumodai 3-chome Suita-shi ; Osaka-fu JPX) Suzuk, Antiparkinsonian agent.
    상세보기
  • Palfreyman Michael G. (Fegersheim FRX) McDonald Ian A. (Truchtersheim FRX), Compounds and methods for treating depression.
    상세보기
  • Sheth Prabhakar R. (Pearl River NY) Tossounian Jacques L. (Pine Brook NJ), Hydrodynamically balanced controlled release compositions containing L-dopa and a decarboxylase inhibitor.
    상세보기
  • Pack Howard M. (12 Herkimer Rd. Scarsdale NY 10583), Method and composition for reducing weight.
    상세보기
  • Fahn Stanley (155 Edgars La. Hastings-on-Hudson NY 10706), Method and compositions of treating Parkinsonisms with levodopa and 3′,4′-dihydroxy-2-methylisopropiophenone.
    상세보기
  • Palfreyman Michael G. (Fegersheim FRX) McDonald Ian A. (Truchtersheim FRX), Method for treating depression.
    상세보기
  • Scriabine Alexander (Ambler PA), Method of treating hypertension.
    상세보기
  • Mori Tadashi (Kyoto JPX) Nakajima Teruo (Osaka JPX), Pharmaceutical composition and method for treatment of psychomotor excitement.
    상세보기
  • Seyfried Christoph (Darmstadt DT) Nowak Herbert (Darmstadt DT), Pharmaceutical preparation and method for treatment of parkinsonism.
    상세보기
  • Schor Joseph M. (Locust Valley NY) Nigalaye Ashok (Elmhurst NY) Gaylord Norman G. (New Providence NJ), Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose.
    상세보기
  • Dempski Robert E. (Dresher PA) Mehta Gunvant N. (Lansdale PA) Saboe Joseph C. (Norristown PA), Sustained release indomethacin.
    상세보기
  • Schor Joseph M. (Locust Valley NY) Nigalaye Ashok (Jackson Heights NY) Gaylord Norman G. (New Providence NJ), Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose.
    상세보기
  • Hammond Michael Douglas (Chesham EN) Schneider Cyril (Whitton EN), Treatment of ethanol withdrawal symptoms with levodopa.
    상세보기
  • Holland Donald R. (Indianapolis IN), Treatment of hypertension with fluoxetine and l-5-hydroxytryptophane.
    상세보기

    • 이 특허를 인용한 특허 (32)

    1. Han,Chien Hsuan; Hsu,Larry; Hsu,Ann F., Combination immediate release controlled release levodopa/carbidopa dosage forms.
      상세보기
    2. Dempski Robert E. (Dresher PA) Scholtz Edward C. (King of Prussia PA) Nibbelink Donald W. (Lansdale PA) Reines Scott A. (New Hope PA), Controlled release combination of carbidopa/levodopa.
      상세보기
    3. Hsu, Ann; Kou, Jim H.; Alani, Laman Lynn, Controlled release formulations of levodopa and uses thereof.
      상세보기
    4. Hsu, Ann; Kou, Jim H.; Alani, Laman Lynn, Controlled release formulations of levodopa and uses thereof.
      상세보기
    5. Hsu, Ann; Kou, Jim H.; Alani, Laman Lynn, Controlled release formulations of levodopa and uses thereof.
      상세보기
    6. Hsu, Ann; Kou, Jim H.; Alani, Laman Lynn, Controlled release formulations of levodopa and uses thereof.
      상세보기
    7. Hsu, Ann; Kou, Jim; Alani, Laman, Controlled release formulations of levodopa and uses thereof.
      상세보기
    8. Hsu, Ann; Kou, Jim; Alani, Laman, Controlled release formulations of levodopa and uses thereof.
      상세보기
    9. Nirmal Mulye, Controlled release oral dosage for suitable for oral administration.
      상세보기
    10. Yacoby-Zeevi, Oron, DOPA decarboxylase inhibitor compositions.
      상세보기
    11. Yacoby-Zeevi, Oron, Dopa decarboxylase inhibitor compositions.
      상세보기
    12. Jerzewski Robert L. (East Millstone NJ) Wong Thomas M. (North Brunswick NJ) Gryziewicz Lewis J. (North Brunswick NJ) Jain Nemichand B. (Monmouth Junction NJ) Thakur Ajit B. (East Brunswick NJ), Fosinopril tablet formulations.
      상세보기
    13. Chou, Kang-Jye; Guo, Hong; Ashton, Paul; Shimizu, Robert W.; Watson, David A., Injectable sustained release delivery devices.
      상세보기
    14. Ueki, Yosuke; Suzuki, Yasuyuki; Fujioka, Satoshi, Method for stabilizing anti-dementia drug.
      상세보기
    15. Ueki, Yosuke; Suzuki, Yasuyuki; Fujioka, Satoshi, Method for stabilizing anti-dementia drug.
      상세보기
    16. Ashton, Paul, Method for treating and/or preventing retinal diseases with sustained release corticosteroids.
      상세보기
    17. Kranzler, Jay D.; Rao, Srinivas G., Methods of treating fibromyalgia syndrome, chronic fatigue syndrome and pain.
      상세보기
    18. Kranzler, Jay D.; Rao, Srinivas G., Methods of treating fibromyalgia syndrome, chronic fatigue syndrome and pain.
      상세보기
    19. Blight, Andrew R.; Cohen, Ron, Methods of using sustained release aminopyridine compositions.
      상세보기
    20. Rao, Srinivas G.; Gendreau, Michael; Kranzler, Jay D., Milnacipran for the long-term treatment of fibromyalgia syndrome.
      상세보기
    21. Hsu, Ann; Dong, Liang C.; Ding, Amy; Gupta, Suneel, Muco-adhesive, controlled release formulations of levodopa and/or esters of levodopa and uses thereof.
      상세보기
    22. Sakaguchi Masao (Ikeda JPX) Honda Susumu (Nishinomiya JPX) Nishimura Osamu (Kawanishi JPX), Novel polypeptides and production thereof.
      상세보기
    23. Wenzel Udo (Halle DEX) Weber Gunther (Zwickau DEX) Metzner Jurgen (Halle DEX) Darr Alfred (Leipzig DEX) Freitag Sabine (Zwickau DEX) Flother Frank-Ulrich (Schaffhausen-Herblingen CHX) Albert Frank-Mi, Orally administrable drugs for the treatment of central dopamine deficiency conditions.
      상세보기
    24. Sabel Bernhard A. (Egmating DEX) Freese Andrew (Jamaica Plain MA) Saltzman William M. (Baltimore MD) During Matthew J. (Westport CT), Polymeric device for controlled drug delivery to the CNS.
      상세보기
    25. Mulye,Nirmal, Process for preparing sustained release tablets.
      상세보기
    26. Blight, Andrew R.; Cohen, Ron, Sustained release aminopyridine composition.
      상세보기
    27. Chen Jianbing ; Ashton Paul, Sustained release drug delivery devices.
      상세보기
    28. Guo, Hong; Ashton, Paul, Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof.
      상세보기
    29. Guo, Hong; Ashton, Paul, Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof.
      상세보기
    30. Guo, Hong; Ashton, Paul, Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof.
      상세보기
    31. Guo, Hong; Ashton, Paul, Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof.
      상세보기
    32. Hong Guo ; Paul Ashton, Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof.
      상세보기

    관련 콘텐츠

    섹션별 컨텐츠 바로가기

    AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

    AI-Helper 아이콘
    AI-Helper
    안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
    ※ AI-Helper는 부적절한 답변을 할 수 있습니다.

    선택된 텍스트

    맨위로