초록 ▼

Collagen-based compositions for augmenting soft tissue, wound dressings, implants, injectable formulations or other drug delivery systems, comprising resorbable collagen matrix beads, the beads having an average pore size of from 50 to 350 microns, and the collagen comprising from 1 to 30% by volume

Collagen-based compositions for augmenting soft tissue, wound dressings, implants, injectable formulations or other drug delivery systems, comprising resorbable collagen matrix beads, the beads having an average pore size of from 50 to 350 microns, and the collagen comprising from 1 to 30% by volume of the beads, the collagen matrix being sufficiently open to stimulate cellular ingrowth therethrough and yet sufficiently stiff and non-compressible to fill and protect a wound, and the formulation being sufficiently moisture and gas permeable to prevent liquid pooling on a wound and to permit sufficient oxygen diffusion for promoting wound healing.

대표청구항 ▼

A wound dressing or implant comprising resorbable, porous collagen matrix beads having particle sizes of from about 100 to 4000 microns, the beads having an average pore size of from about 50 to 350 microns, and the collagen comprising from 1 to 30% by volume of the beads, the porous collagen matrix

A wound dressing or implant comprising resorbable, porous collagen matrix beads having particle sizes of from about 100 to 4000 microns, the beads having an average pore size of from about 50 to 350 microns, and the collagen comprising from 1 to 30% by volume of the beads, the porous collagen matrix forming a skeleton providing a volume sufficient for cells to attach and grow into the matrix and being stiff and non-compressible to a degree sufficient to fill and protect a wound, the dressing or implant having a degree of moisture and gas permeability sufficient to prevent liquid pooling on a wound and to permit sufficient oxygen diffusion for promoting wound healing.