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Calcification mitigation of implantable bioprostheses 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61F-002/24
출원번호 US-0039295 (1987-04-17)
발명자 / 주소
  • Nashef Aws S. (Huntington Beach CA)
출원인 / 주소
  • Baxter Travenol Laboratories, Inc. (Deerfield IL 02)
인용정보 피인용 횟수 : 53  인용 특허 : 8

초록 ▼

A process for treating biological tissue prior to implantation to mitigate the calcification of the tissue following implantation comprises incorporating acetylsalicylic acid into the tissue in an amount effective to reduce calcification of the tissue after it is implanted. In accordance with one em

대표청구항 ▼

A process for treating animal biological tissue prior to implantation in an animal to reduce calcification of said tissue following implantation, which comprises: (a) fixing said tissue under tissue-fixing conditions, and (b) contacting said tissue with a solution of acetylsalicylic acid for a time

이 특허에 인용된 특허 (8)

  1. Nimni, Marcel E.; Cheung, David T., Coating for bioprosthetic device and method of making same.
    상세보기
  2. Hudgin Donald Edward (Princeton Junction NJ) Blair Edgar Allan (Cranbury NJ), Hydrophilic or hydrogel carrier systems such as coatings, body implants and other articles.
    상세보기
  3. Carpentier Alain (Paris FRX) Carpentier Sophie (Paris CA FRX) Nashef Aws S. (Costa Mesa CA), Implantable biological tissue and process for preparation thereof.
    상세보기
  4. Lentz David J. (Mission Viejo CA) Pollock Elisabeth M. (Yorba Linda CA), Method for inhibiting mineralization of natural tissue during implantation.
    상세보기
  5. Nashef Aws S. (Costa Mesa CA), Polymer incorporation into implantable biological tissue to inhibit calcification.
    상세보기
  6. Marconi Walter (S. Donato Mi ITX) Bartoli Francesco (Rome ITX) Pittalis Francesco (Rome ITX), Preparation of biocompatible materials by immobilization of apyrase.
    상세보기
  7. Dewanjee, Mrinal K., Treatment of collagenous tissue with glutaraldehyde and aminodiphosphonate calcification inhibitor.
    상세보기
  8. Mueller Karl F. (New York NY) Good William R. (Yorktown Height NY), Water-insoluble hydrophilic copolymers used as carriers for medicaments and pesticides.
    상세보기

이 특허를 인용한 특허 (53)

  1. Chandrashenkhar P. Pathak ; Mark A. Moore ; Richard E. Phillips, Anticalcification treatments for fixed biomaterials.
    상세보기
  2. Paul Edward Ashworth ; Matthew Frank Ogle ; Daniel Paul McTavish ; Sheila Jeanne Kelly ; Andrea L. Johnson, Biocompatible prosthetic tissue.
    상세보기
  3. Jaffe Norman (Dana Point CA) Hancock Warren B. (Newport Beach CA), Biological material pre-fixation treatment.
    상세보기
  4. Tian, Bin; Davidson, Jim, Biological tissue for surgical implantation.
    상세보기
  5. Kim Young Ha (Seoul KRX) Park Ki Dong (Seoul KRX) Han Dong Keun (Seoul KRX) Kim Hack Joo (Seoul KRX), Bioprosthetic heart valves having high calcification resistance.
    상세보기
  6. Dove, Jeffrey S.; Dobler, Darin P.; Davidson, James A.; Wright, Gregory A., Bioprosthetic tissue with reduced calcification.
    상세보기
  7. Dove, Jeffery; Dobler, Darin; Davidson, Jim; Wright, Gregory, Capping bioprosthetic tissue to reduce calcification.
    상세보기
  8. Dove, Jeffery; Dobler, Darin; Davidson, Jim; Wright, Gregory A., Capping bioprosthetic tissue to reduce calcification.
    상세보기
  9. Dove, Jeffrey S.; Dobler, Darin P.; Davidson, James A.; Wright, Gregory A., Capping bioprosthetic tissue to reduce calcification.
    상세보기
  10. Dove, Jeffrey S.; Dobler, Darin P.; Davidson, James A.; Wright, Gregory A., Capping bioprosthetic tissue to reduce calcification.
    상세보기
  11. Pathak C. P. ; Moore Mark A., Cross-linking tissue with a compound having a C.sub.8 to C.sub.40 aliphatic chain.
    상세보기
  12. Carpentier, Sophie M.; Carpentier, Alain F., Double cross-linkage process to enhance post-implantation bioprosthetic tissue durability.
    상세보기
  13. Hiles, Michael C.; Patel, Umesh H., Dried collagenous biomaterial medical device.
    상세보기
  14. Moran, Christopher J.; Bleyer, Mark W.; Kozma, Thomas G.; Patel, Umesh H., Embolization device.
    상세보기
  15. Moran, Christopher J.; Kozma, Thomas G.; Patel, Umesh H.; Bleyer, Mark W., Embolization device.
    상세보기
  16. Hiles, Michael C.; Patel, Umesh H., Freeze-dried collagenous biomaterial medical sponge device.
    상세보기
  17. Yang Jun ; Shen Shih-Hwa, Glutaraldehyde-fixed bioprostheses.
    상세보기
  18. Cook, William A.; Hiles, Michael C.; Kozma, Thomas G.; Patel, Umesh H., Graft prosthesis, material and methods.
    상세보기
  19. Cook, William A.; Hiles, Michael C.; Kozma, Thomas G.; Patel, Umesh H., Graft prosthesis, materials and methods.
    상세보기
  20. Cook, William A.; Hiles, Michael C.; Kozma, Thomas G.; Patel, Umesh H., Graft prosthesis, materials and methods.
    상세보기
  21. Cook, William A.; Hiles, Michael C.; Kozma, Thomas G.; Patel, Umesh H., Graft prosthesis, materials and methods.
    상세보기
  22. Cook, William A.; Hiles, Michael C.; Kozma, Thomas G.; Patel, Umesh H., Graft prosthesis, materials and methods.
    상세보기
  23. Munnelly, Amy E.; Dove, Jeffrey S.; Lee, Minsey, Method and apparatus for preparing a contoured biological tissue.
    상세보기
  24. Mark A. Moore ; David T. Cheung ; Gerald L. Mechanic ; Brian K. Mcilroy, Method for extracting lipids from tissue samples using high osmolality storage medium and product.
    상세보기
  25. Levy Robert J. ; Hirsch Danielle,ILX, Method of making calcification-resistant bioprosthetic tissue.
    상세보기
  26. Huergo Concepcion C. (Havana CUX) Sierra Gonzalez Victoriano G. (Villa Santa Clara CUX) Gutierrez Vazquez Maria M. (Bejucal CUX) Bisset Jorrin Gonzalo (Havana CUX) Garcia Imia Luis G. (Havana CUX) de, Method of producing Neisseria meningitidis B vaccine, and vaccine produced by method.
    상세보기
  27. Tian, Bin; Davidson, Jim, Method of treating glutaraldehyde-fixed pericardial tissue with a non-aqueous mixture of glycerol and a C.
    상세보기
  28. Cheung,David T., Method to treat collagenous connective tissue for implant remodeled by host cells into living tissue.
    상세보기
  29. Yang Jun ; Shen Shih-Hwa, Methods for mitigating calcification and improving durability in glutaraldehyde-fixed bioprostheses and articles manuf.
    상세보기
  30. Davidson, Jim; Dove, Jeff; Dobler, Darin, Methods for pre-stressing and capping bioprosthetic tissue.
    상세보기
  31. Dove, Jeffrey S.; Tod, Tara J., Methods for stabilizing a bioprosthetic tissue by chemical modification of antigenic carbohydrates.
    상세보기
  32. Xu, Dengfeng; Dove, Jeffrey S., Methods for treating bioprosthetic tissue using a nucleophile/electrophile in a catalytic system.
    상세보기
  33. Dove, Jeffrey S.; Tian, Bin; Schneider, Ralph; Cohen, Jeffrey S.; Jankovic, Ivan; Migliazza, John F.; Wright, Gregory A.; Young, James M.; Campbell, Louis A., Methods of conditioning sheet bioprosthetic tissue.
    상세보기
  34. Dove, Jeffrey S.; Tian, Bin; Schneider, Ralph; Cohen, Jeffrey S.; Jankovic, Ivan; Migliazza, John F.; Wright, Gregory A.; Young, James M.; Campbell, Louis A., Methods of conditioning sheet bioprosthetic tissue.
    상세보기
  35. Dove, Jeffrey S.; Tian, Bin; Schneider, Ralph; Cohen, Jeffrey S.; Jankovic, Ivan; Migliazza, John F.; Wright, Gregory A.; Young, James; Campbell, Louis A., Methods of conditioning sheet bioprosthetic tissue.
    상세보기
  36. Dove, Jeffrey S.; Tian, Bin; Schneider, Ralph; Cohen, Jeffrey S.; Jankovic, Ivan; Migliazza, John F.; Wright, Gregory A.; Young, James; Campbell, Louis A., Methods of conditioning sheet bioprosthetic tissue.
    상세보기
  37. Schneider, Ralph; Tian, Bin; Dove, Jeffrey S.; Cohen, Jeff; Jankovic, Ivan; Migliazza, John F.; Wright, Gregory A.; Young, James; Campbell, Louis A., Methods of conditioning sheet bioprosthetic tissue.
    상세보기
  38. Tian, Bin; Schneider, Ralph; Dove, Jeffrey S.; Cohen, Jeff; Jankovic, Ivan; Migliazza, John F.; Wright, Gregory A.; Young, James; Campbell, Louis A., Methods of conditioning sheet bioprosthetic tissue.
    상세보기
  39. Hiles, Michael C.; Patel, Umesh H., Multi-formed collagenous biomaterial medical device.
    상세보기
  40. Hiles, Michael C.; Patel, Umesh H., Multi-formed collagenous biomaterial medical device.
    상세보기
  41. Hiles, Michael C.; Patel, Umesh H., Multi-formed collagenous biomaterial medical device.
    상세보기
  42. Hiles, Michael C.; Patel, Umesh H., Multi-formed collagenous biomaterial medical device for use in wound care.
    상세보기
  43. McIlroy Brian K. ; Moore Mark A. ; Phillips Richard E., Non-calcific biomaterial by glutaraldehyde followed by oxidative fixation.
    상세보기
  44. Torrianni, Mark W., Process for reducing mineralization of tissue used in transplantation.
    상세보기
  45. Torrianni,Mark W., Process for reducing mineralization of tissue used in transplantation.
    상세보기
  46. Pathak C. P. ; Moore Mark A. ; Phillips Richard E., Tissue crosslinking for bioprostheses using activated difunctional or polyfunctional acids.
    상세보기
  47. Goldstein Steven, Treated tissue for implantation and methods of preparation.
    상세보기
  48. Goldstein Steven (Atlanta GA), Treated tissue for implantation and methods of preparation.
    상세보기
  49. Orton E. Christopher, Treated tissue for implantation and methods of treatment and use.
    상세보기
  50. Orton E. Christopher, Treated tissue for implantation and methods of treatment and use.
    상세보기
  51. Orton E. Christopher, Treated tissue for implantation and methods of treatment and use.
    상세보기
  52. Carpentier, Alain F.; Carpentier, Sophie; Cunanan, Crystal M.; Quintero, Lillian J.; Helmus, Michael N.; Loshbaugh, Christine; Sarner, H. Chris, Treating biological tissues to mitigate post-implantation calcification.
    상세보기
  53. Carpentier, Sophie M.; Carpentier, Alain F., Treatment of bioprosthetic tissues to mitigate post implantation calcification.
    상세보기

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