초록 ▼

A biosensor includes an optically dense body provided with a coating sensitized to a specific assay species, and an input and output coupling structure. Light signal response is enhanced by incorporating a partially reflecting, partially transmitting medium between the coupling structure and the opt

A biosensor includes an optically dense body provided with a coating sensitized to a specific assay species, and an input and output coupling structure. Light signal response is enhanced by incorporating a partially reflecting, partially transmitting medium between the coupling structure and the optically dense body having a lower refractive index. The thickness of such medium is chosen so that light may be coupled by frustrated total internal reflection and to enable the medium to serve as a resonant mirror.

대표청구항 ▼

A biosensor comprising: an optically dense body having a coating sensitized for a given assay species, light coupling means positioned in operative adjacent relation to the optically dense body for directing light into and out of the same, and means operatively associated with the light coupling mea

A biosensor comprising: an optically dense body having a coating sensitized for a given assay species, light coupling means positioned in operative adjacent relation to the optically dense body for directing light into and out of the same, and means operatively associated with the light coupling means for esablishing a mirrored resonant cavity within the optically dense body by frustrated total internal reflection, including a light reflecting and partially transmissive medium operatively interposed between the optically dense body and the light coupling means.