초록 ▼

A syringe provides for the isolated storage of two components of a medicament until immediately prior to use of the syringe. One liquid component is stored in a collapsible chamber of a sealed capsule within a hollow plunger stem of the syringe, and the other component beneath the head of the plunge

A syringe provides for the isolated storage of two components of a medicament until immediately prior to use of the syringe. One liquid component is stored in a collapsible chamber of a sealed capsule within a hollow plunger stem of the syringe, and the other component beneath the head of the plunger. A double headed needle arrangement between the head and stem of the plunger is caused to penetrate the plunger head and the capsule when the syringe is to be used so that the plunger may be drawn back to exhaust the contents of the capsule chamber into admixture with the component stored beneath the head of the plunger. Communication through the double headed needle arrangement is then interrupted before the plunger is used to eject the syringe contents through an external needle fitted to the syringe.

대표청구항 ▼

A syringe for the administration of a medicament having two components requiring separate storage comprises: a barrel having a neck at one end, a penetrable closure for said neck, means mounted on said neck for receiving a double ended needle with one end thereof in penetrating relationship with sai

A syringe for the administration of a medicament having two components requiring separate storage comprises: a barrel having a neck at one end, a penetrable closure for said neck, means mounted on said neck for receiving a double ended needle with one end thereof in penetrating relationship with said closure, a hollow plunger stem movable with the barrel, a capsule defining a sealed collapsible chamber comprising a first, liquid component of the medicament and entering within the hollow plunger stem, a plunger head sealingly slidable within the barrel to isolate a second component of the medicament stored within the barrel beyond the plunger head, means coupling the plunger head and the plunger stem, hollow needle means located at the inner end of the plunger stem between the capsule and the plunger head, and means to drive the capsule towards the plunger head whereby the needle means is caused to pierce said capsule and place the interior of the capsule in communication with the hollow needle means, the coupling means comprising two relatively axially movable parts having twist coupling means such that they are capable of assuming two alternative axially spaced relative positions, in each of which they can be retained against relative axial movement in at least one direction, the longitudinal position of the plunger head relative to the needle in a first of the positions, in which the parts can be retained against movement toward one another, being such that the needle does not pierce the head, and in a second of the positions, in which the parts can be retained against movement away from each other, being such that the needle does pierce the head; wherein the first of said axially movable parts is a sleeve attached to one of the head and the plunger stem, and the second of said parts is a hollow stem attached to the other of the head and the plunger stem and telescopically entering the sleeve, the sleeve having an axially asymmetric opening, and the stem having an asymmetric section having at least one orientation in which it can move axially into said opening, and at least one neck permitting the opening in the sleeve to be rotated out of said at least one orientation in at least the second of said axially spaced positions.