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Injectable composition for inductive bone repair 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-035/32
  • A61K-037/12
  • C07K-015/20
  • C12P-021/00
출원번호 US-0133532 (1987-12-16)
발명자 / 주소
  • Nathan Ranga (Newark CA) Thompson Andrea (Mountain View CA) Seyedin Saeid (Sunnyvale CA)
출원인 / 주소
  • Collagen Corporation (Palo Alto CA 02)
인용정보 피인용 횟수 : 58  인용 특허 : 8

초록

Aqueous suspensions of fibrillar atelopeptide collagen and osteogenic factor are effective injectable preparations for the repair of bone defects.

대표청구항

An injectable bone growth-inducing composition comprising an injectable aqueous suspension of fibrillar atelopeptide collagen and at least partially purified osteogenic factor, wherein the fibrillar atelopeptide collagen and the at least partially purified osteogenic factor are in the form of a copr

이 특허에 인용된 특허 (8)

  1. Jefferies Steven R. (5802 Leith Walk Baltimore MD 21239), Bone graft material for osseous defects and method of making same.
  2. Urist Marshall R. (Pacific Palisades CA), Bone morphogenetic protein.
  3. Urist Marshall R. (Pacific Palisade CA), Bone morphogenetic protein process.
  4. Nathan Ranga (Newark CA) Seyedin Saied (Mountain View CA) Piez Karl (Menlo Park CA) Bentz Hanne (Palo Alto CA), Inductive collagen based bone repair preparations.
  5. Wallace Donald G. (Menlo Park CA) Smestad Thomas L. (Palo Alto CA) McPherson John M. (Sunnyvale CA) Piez Karl A. (Menlo Park CA) Seyedin Saeid (Sunnyvale CA) Armstrong Rosa (Palo Alto CA), Methods of bone repair using collagen.
  6. Glowacki Julianne (Jamaica Plain MA) Pharriss Bruce B. (Palo Alto CA), Osteogenic composition and method.
  7. Seyedin Saeid (Mountain View CA) Thomas Thomas (Davis CA), Partially purified bone-inducing factor.
  8. Seyedin Saeid (Mt. View CA) Thomas Thomas (Palo Alto CA), Partially purified osteogenic factor and process for preparing same from demineralized bone.

이 특허를 인용한 특허 (58)

  1. Mohan, Suneeth Elizabeth; Shimko, Daniel Andrew, Bone filler material.
  2. Kwan Michael K. ; Pacetti Stephen D. ; Yamamoto Ronald K., Bone grafting matrix.
  3. Kwan Michael K. ; Pacetti Stephen D. ; Yamamoto Ronald K., Bone grafting matrix.
  4. Kwan, Michael K.; Pacetti, Stephen D.; Yamamoto, Ronald K., Bone grafting matrix.
  5. Thorne, Kevin J., Bone growth particles and osteoinductive composition thereof.
  6. Thorne, Kevin J., Bone growth particles and osteoinductive composition thereof.
  7. Akella, Rama; Garrett, Ian Ross; Wen, Hai Bo; Li, Shuliang; Acker, Dean M.; Wilhelm, Nichole, Bone void fillers.
  8. Shimura,Takesada; Toriyama,Satsuki, Cartilage/Bone inducing materials for preparation.
  9. Shimura, Takesada; Toriyama, Satsuki, Cartilage/bone inducing materials for reparation.
  10. Li Shu-Tung (Oakland NJ), Charged collagen particle-based delivery matrix.
  11. Jones Richard E. ; Li Mike T., Collagen formulations.
  12. Robert D. Torgerson ; John Uhoch ; Francis B. Maddalo ; Stephen N. Eldridge, Collagen hemostatic fibers.
  13. Francis B. Maddalo ; Mark V. Iampietro ; Stephen N. Eldridge ; Robert D. Torgerson, Collagen hemostatic foam.
  14. Shimp, Lawrence A., Collagen matrix.
  15. Shimp, Lawrence A., Collagen matrix.
  16. Schmidt Karlheinz,DEX, Complex active ingredient for the production of biological parts, especially organs for living organisms: method for th.
  17. Schmidt Karlheinz,DEX, Complex for inducing bone growth in the mastoid cavity.
  18. Han, Bo; Nimni, Marcel E., Composite containing collagen and elastin as a dermal expander and tissue filler.
  19. Thorne, Kevin J., Composition and process for bone growth and repair.
  20. Akella, Rama; Ranieri, John, Compositions and methods for promoting myocardial and peripheral angiogenesis.
  21. Atkinson, Brent; Benedict, James J., Compositions for regeneration and repair of cartilage lesions.
  22. Gross, Jeffrey M.; Peckham, Steve; Scifert, Jeffrey L.; Badura, Jeffrey; Scarborough, Nelson; Vickers, Scott, Compositions for treating bone defects.
  23. Gross, Jeffrey M.; Peckham, Steve; Scifert, Jeffrey; Badura, Jeffrey; Scarborough, Nelson; Vickers, Scott, Compositions for treating bone defects.
  24. Shimp, Lawrence A.; Knaack, David, Coupling agents for orthopedic biomaterials.
  25. Shimp,Lawrence A.; Knaack,David, Coupling agents for orthopedic biomaterials.
  26. Drapeau, Susan J.; Chamness, Kathy L.; McKay, William F., Demineralized bone matrix devices.
  27. Evans, Douglas G.; Goldman, Scott M.; Kronengold, Russell T., Devices and methods for treating defects in the tissue of a living being.
  28. Evans, Douglas G; Goldman, Scott M.; Kronengold, Russell T., Devices and methods for treating defects in the tissue of a living being.
  29. Evans, Douglas G; Goldman, Scott M.; Kronengold, Russell T., Devices and methods for treating defects in the tissue of a living being.
  30. Evans, Douglas G; Goldman, Scott M.; Kronengold, Russell T., Devices and methods for treating defects in the tissue of a living being.
  31. Evans, Douglas G; Goldman, Scott M.; Kronengold, Russell T., Devices and methods for treating defects in the tissue of a living being.
  32. Evans, Douglas G; Goldman, Scott M.; Kronengold, Russell T., Devices and methods for treating defects in the tissue of a living being.
  33. Benedict, James J.; Damien, Christopher J., Implantable putty material.
  34. Benedict, James J.; Damien, Christopher J., Implantable putty material.
  35. Louis Junker ; Michael Lewis ; Robert Nelson, Isolation of purified TGF- .beta.1 and TGF -.beta.2 from bone tissue.
  36. Drapeau, Susan J.; Chamness, Kathy L.; McKay, William F., Malleable implants containing demineralized bone matrix.
  37. Drapeau, Susan J.; Chamness, Kathy L.; McKay, William F., Malleable implants containing demineralized bone matrix.
  38. Drapeau, Susan J.; Remsen, Kathy L.; McKay, William F.; Scarborough, Nelson L., Malleable implants containing demineralized bone matrix.
  39. Drapeau, Susan J; Remsen, Kathy L; McKay, William F, Malleable implants containing demineralized bone matrix.
  40. Drapeau, Susan J; Remsen, Kathy L; McKay, William F; Scarborough, Nelson L, Malleable implants containing demineralized bone matrix.
  41. McKay, William F.; Scifert, Jeffrey L.; Remsen, Kathy L.; Billy, Didier; Gillissen, Mirian; Vickers, Scott M., Malleable multi-component implants and materials therefor.
  42. McKay, William F.; Scifert, Jeffrey L.; Remsen, Kathy; Billy, Didier; Gillissen, Mirian; Vickers, Scott M., Malleable multi-component implants and materials therefor.
  43. Lloyd Wolfinbarger, Jr., Method and process for the production of collagen preparations from invertebrate marine animals and compositions thereof.
  44. Wolfinbarger, Jr., Lloyd, Method and process for the production of collagen preparations from invertebrate marine animals and compositions thereof.
  45. Benedict,James J.; Ranieri,John P.; Whitney,Marsha L.; Akella,Rama, Method of promoting natural bypass.
  46. Ashkar Samy ; Atala Anthony, Methods and compositions for programming an organic matrix for remodeling into a target tissue.
  47. Moehlenbruck, Jeffrey William; Ranieri, John Paul, Methods and compositions for treating intervertebral disc degeneration.
  48. Damien Christopher J. (Denver CO) Benedict James J. (Golden CO) Poser James W. (Lawrenceville NJ), Osteogenic product and process.
  49. Seyedin Saeid (Saratoga CA) Thomas Thomas (West Roxbury MA) Bentz Hanne (Newark CA) Ellingsworth Larry (San Jose CA) Armstrong Rosa (Palo Alto CA), Polypeptide cartilage-inducing factors found in bone.
  50. Schmidt Karlheinz,DEX, Process for producing active agent complexes.
  51. Benedict James J. ; Ranieri John P. ; Whitney Marsha L., Protein mixtures to induce therapeutic angiogenesis.
  52. Thorne, Kevin, Rapid isolation of osteoinductive protein mixtures from mammalian bone tissue.
  53. Thorne, Kevin; Akella, Rama, Rapid isolation of osteoinductive protein mixtures from mammalian bone tissue.
  54. Lawin Timothy P. ; Klein Dean, Tissue injectable composition and method of use.
  55. Yamamoto, Ronald K.; Kwan, Michael K.; Pacetti, Stephen D., Tissue repair matrix.
  56. Yamamoto, Ronald K.; Kwan, Michael K.; Pacetti, Stephen D., Tissue repair matrix.
  57. Kuberasampath Thangavel (Medway MA) Cohen Charles M. (Medway MA) Oppermann Hermann (Medway MA) Ozkaynak Engin (Milford MA) Rueger David C. (Hopkinton MA) Pang Roy H. L. (Etna NH), Treatment to prevent loss of and/or increase bone mass in metabolic bone diseases.
  58. Kuberasampath,Thangavel; Cohen,Charles M.; Oppermann,Herrmann; Ozkaynak,Engin; Rueger,David C.; Smart,John E.; Pang,Roy H. L., Treatment to prevent loss of and/or increase bone mass in metabolic bone diseases.
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