초록 ▼

A vitamin-containing granule comprising one or more compounds selected from the group consisting of vitamin B6, vitamin B2, nicotinamide and a pantothenic acid salt, and a binding agent, said compound or compounds accounting for 90 to 99 weight percent of the granules on the dry basis, can be prepar

A vitamin-containing granule comprising one or more compounds selected from the group consisting of vitamin B6, vitamin B2, nicotinamide and a pantothenic acid salt, and a binding agent, said compound or compounds accounting for 90 to 99 weight percent of the granules on the dry basis, can be prepared by spray-coating the powders of said compound or compounds with a solution containing a binder while maintaining the powders in a fluidized state in a fluidized-bed granulation apparatus. The granules are highly flowable and blend well with other medicaments, granules, additives, and so on. In addition to this, the granules are excellent in compressibility so that they can be processed into tablets with small amounts of excipients, and the tablets therefrom have satisfactory high hardness.

대표청구항 ▼

A vitamin-containing granule comprising one or more compounds selected from the group consisting of vitamin B6, vitamin B2, nicotinamide and a pantothenic acid salt, and a water-soluble cellulose as a binding agent, said one or more compounds accounting for about 95 to 99 weight percent of the granu

A vitamin-containing granule comprising one or more compounds selected from the group consisting of vitamin B6, vitamin B2, nicotinamide and a pantothenic acid salt, and a water-soluble cellulose as a binding agent, said one or more compounds accounting for about 95 to 99 weight percent of the granules on a dry basis.