초록 ▼

Cultivation tank (1) for continuous cultivation of cells or micro-organisms, containing a rotating separating device (11,12) for separating suspended cells from cultivation liquid (10) supplied continuously through a supply (4) and passed through the separating device (11,12) from the outside to the

Cultivation tank (1) for continuous cultivation of cells or micro-organisms, containing a rotating separating device (11,12) for separating suspended cells from cultivation liquid (10) supplied continuously through a supply (4) and passed through the separating device (11,12) from the outside to the inside, cell free liquid being continuously discharged from within the separating device (11,12), the rotating parts (11,12) of the separating device being formed so that within the outer circumference a zone (15) is formed of a vortex-free, vertical rotating column of cultivation liquid from which the cells are radially thrown out by centrifugal forces into the surrounding liquid (10) through openings in the outlet circumference (11) of the separating device (11,12) are considerably greater than the size of the cells.

대표청구항 ▼

Apparatus for the continuous cultivation of cells of a predetermined size of organisms selected from the group consisting of micro-organisms, and animal and vegetable cells, in a culture liquid, which apparatus contains a cultivation tank provided with a stirring device, an inlet for fresh cultivati

Apparatus for the continuous cultivation of cells of a predetermined size of organisms selected from the group consisting of micro-organisms, and animal and vegetable cells, in a culture liquid, which apparatus contains a cultivation tank provided with a stirring device, an inlet for fresh cultivation medium, an outlet for used culture liquid, a rotating separating device comprising rotating parts for separating suspended cells or cell-carrying particles from culture liquid passed through the separating device which separating device is provided with a collecting space for culture liquid rendered essentially free of said cells into which the outlet for the culture liquid, rendered free of the cells, debouches, characterized in that the rotating parts of the separating device are formed in a manner such that, within the surface of revolution in which the outside circumference of the rotating parts rotates about an axis of rotation, a zone is formed containing a vortex-free axial rotating column of culture liquid from which the cells which are in suspension are thrown back by centrifugal forces into the surrounding culture liquid through openings in the outside circumference of the separating device which are considerably larger than the size of the cells to be separated, said openings being considerably larger than said predetermined cell size.