초록 ▼

A drug reservoir containing an active substance such as a drug is formed on an adhesive layer which can adhere to an oral mucosal membrane. A polymer, which does not dissolve with saliva, is further coated on the drug reservoir as a drug release controlling layer to form an entire oral cavity sustai

A drug reservoir containing an active substance such as a drug is formed on an adhesive layer which can adhere to an oral mucosal membrane. A polymer, which does not dissolve with saliva, is further coated on the drug reservoir as a drug release controlling layer to form an entire oral cavity sustained release dosage form. A drug impermeable layer can be formed between the adhesive layer and the drug reservoir.

대표청구항 ▼

A controlled release dosage form for application to oral cavity tissue, comprising: an adhesive layer having a first side adherable to oral cavity tissue; a reservoir containing an active substance positioned over a second side of the adhesive layer; and a controlled release layer covering the reser

A controlled release dosage form for application to oral cavity tissue, comprising: an adhesive layer having a first side adherable to oral cavity tissue; a reservoir containing an active substance positioned over a second side of the adhesive layer; and a controlled release layer covering the reservoir and providing for a delayed release of the active substance into the oral cavity wherein the first side of the adhesive layer adherable to oral cavity tissue is left uncovered by the controlled release layer.