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A dispensing apparatus comprises a pressurised dispensing container (3), a housing (2) for the container defining a bore, the container having a body (50) which is axially slidable in the bore, the container having a collapsible metering valve (8) located at a first end (6) of the body for dispensin

A dispensing apparatus comprises a pressurised dispensing container (3), a housing (2) for the container defining a bore, the container having a body (50) which is axially slidable in the bore, the container having a collapsible metering valve (8) located at a first end (6) of the body for dispensing metered quantities of fluid and actuated by axial depression of a valve stem (9) defining a dispensing flowpath, a valve actuator (11) fixedly connected to the housing at a corresponding first end (7) thereof and defining a further dispensing flowpath for product fluid dispensed through the stem, and trigger means (30) operable to urge the container body axially towards the first end of the housing such that the valve stem is depressed by relative movement together of the valve and actuator and thereby dispensing a metered quantity of fluid, wherein the container body defines a chamber (4) and the container includes means (5) dividing the chamber into a product fluid reservoir (25) communicating with the valve and a propellant fluid reservoir (26), the dividing means being movable such that propellant pressure is applied to the product fluid without mixing of the respective fluids. The apparatus is suitable for the nasal administration of insulin.

대표청구항 ▼

A pressurized dispensing container having a tubular body defining a chamber, the container having a collapsible chamber metering valve located at a first end of the body for dispensing metered quantities of fluid and actuated by axial depression of a valve stem defining a dispensing flowpath, the co

A pressurized dispensing container having a tubular body defining a chamber, the container having a collapsible chamber metering valve located at a first end of the body for dispensing metered quantities of fluid and actuated by axial depression of a valve stem defining a dispensing flowpath, the container having piston means dividing the chamber into a product fluid reservoir communicating with the valve and a propellant fluid reservoir, the piston means being movable such that propellant pressure is applied to the product fluid without mixing of the respective fluids, the piston means including a free piston axially slidable within the chamber and dividing the chamber into a first portion constituting the product fluid reservoir located forward of the piston and a second portion constituting the propellant fluid reservoir located rearward of the piston, wherein the piston includes a forward portion of a first material selected to be substantially chemically non-reactive with the product fluid and a rearward portion of a second material selected to be substantially impermeable to the propellant fluid, the piston portions being composited such that the product and propellant fluids respectively do not contact the second and first materials of the piston respectively. Dispensing apparatus for dispensing metered quantities of a pressurized fluid comprising a pressurized dispensing container, a housing for the container defining a bore, the container having a body which is axially slidable in the bore, the container having a collapsible chamber metering valve located at a first end of the body for dispensing metered quantities of fluid and actuated by axial depression of a valve stem defining a dispensing flowpath, a valve actuator fixedly connected to the housing at a corresponding first end thereof and defining a further dispensing flowpath for product fluid dispensed through the stem, and trigger means operable to urge the container body axially towards the first end of the housing such that the valve stem is depressed by relative movement together of the valve and actuator and thereby dispensing a metered quantity of fluid, wherein the container body defines a chamber and the container includes a flexible bag dividing the chamber into a product fluid reservoir communicating with the valve and a propellant fluid reservoir, the bag being movable such that propellant pressure is applied to the product fluid without mixing of the respective fluids, and wherein the interior of the bag defines the product reservoir, the bag including a mouth portion including a thickened annular flange secured in sealing contact with a cooperating flange of the valve and a thickened neck portion formed integrally with the flange and depending rigidly therefrom so as to define an annular space between the neck and the valve. Dispensing apparatus for dispensing metered quantities of a pressurized fluid comprising a pressurized dispensing container, a housing for the container defining a bore, the container having a body which is axially slidable in the bore, the container having a collapsible chamber metering valve located at a first end of the body for dispensing metered quantities of fluid and actuated by axial depression of a valve stem defining a dispensing flowpath, a valve actuator fixedly connected to the housing at a corresponding first end thereof and defining a further dispensing flowpath for product fluid dispensed through the stem, and trigger means operable to urge the container body axially towards the first end of the housing such that the valve stem is depressed by relative movement together of the valve and actuator and thereby dispensing a metered quantity of fluid, wherein the container body defines a chamber and the container includes means dividing the chamber into a product fluid reservoir communicating with the valve and a propellant fluid reservoir, the dividing means being movable such that propellant pressure is applied to the product fluid without mixing of the respective fluids, and wherein the actuator includes inner and outer nested components, the actuator including a break-up nozzle for atomizing dispensed fluid, which nozzle includes swirl inducing ducts defined by groove formations formed in one or other abutting surfaces of the inner and outer nested components of the actuator respectively, which inner nested component includes a first tubular portion defining a bore fitting onto the valve stem, the outer nested component including a second tubular portion fitting onto the first tubular portion, the first tubular portion being provided with an axially extending groove cooperating with the outer component to define a passageway communicating with the nozzle and a radial port communicating between the bore and the passageway.