초록 ▼

Disclosed is a percutaneous access device (PAD) for long-term skin penetration and use as an access port in the body of a patient. The buttonlike device includes a flat skirt for subdermal anchoring of the PAD and a neck through which a tube may extend for transmission of materials to or from the bo

Disclosed is a percutaneous access device (PAD) for long-term skin penetration and use as an access port in the body of a patient. The buttonlike device includes a flat skirt for subdermal anchoring of the PAD and a neck through which a tube may extend for transmission of materials to or from the body. A two-stage porous bed covering the skirt and at least a portion of the neck promotes formation of a tight, infection-free barrier between the percutaneous access device and adjacent tissues, stabilizing the device for long-term use. The first stage of the bed retards downgrowth of epidermal cells for a time sufficient for mature collagen to form in the second stage, thereby permitting the tight dermal/biomaterial interface or barrier to form at a location near the junction of the two stages.

대표청구항 ▼

In a percutaneous access deice including a button having a skirt and a neck integral with and substantially normal to said skirt, said neck and skirt being formed of a semirigid biocompatible material and having a bore therethrough to accommodate a tube, and a porous bed overlying and attached to at

In a percutaneous access deice including a button having a skirt and a neck integral with and substantially normal to said skirt, said neck and skirt being formed of a semirigid biocompatible material and having a bore therethrough to accommodate a tube, and a porous bed overlying and attached to at least a portion of said button, the improvement wherein said porous bed comprises a first stage extending along a portion of said skirt adjacent to said neck and along at least the lower portion of said neck and a second stage formed essentially of a biocompatible material and having pores of a size in the range of about 400-800 microns, said first stage having a total length along said neck and said skirt of at least 0.25 inches and being fabricated of layers of filaments of a diameter in the range of about 0.0004 to 0.015 inches and of a polyurethane material which is the reaction product of dicyclohexyl methane diisocyanate, polytetramethylene ether glycol, and 1,4 butane diol, said layers being formed into a structure having pores of a size in the range of about 50-125 microns, said percutaneous access device, upon implantation of the skirt in subcutaneous tissue adjacent to the dermis, promoting formation of a stable, tight, infection-free biologic seal between said device and adjoining tissue through the downgrowth of epidermal cells through the first stage and the formation of mature collagen in said second stage.