초록 ▼

A method of forming an improved hydrophilic coating by applying on a non-reactive hydrophilic polymer surface layer an osmolality-increasing compound to produce a more stable hydrophilic surface and to produce a more slippery surface in wet condition. The polymer surface layer is treated with a solu

A method of forming an improved hydrophilic coating by applying on a non-reactive hydrophilic polymer surface layer an osmolality-increasing compound to produce a more stable hydrophilic surface and to produce a more slippery surface in wet condition. The polymer surface layer is treated with a solution having above 2% (weight/volume) of an osmolality increasing compound and then the solvent of the solution is evaporated. Osmolality increasing compounds are nontoxic organic or unorganic salts other than trihalogenids, mono- or di- saccharides or sugar alcohols. Preferred compounds are glucose, sorbitol, sodium chloride, sodium citrate, sodium bensoate, calcium chloride, potassium chloride, potassium iodide, potassium nitrate. The solution of the osmolality increasing compound contains preferably a polymer. Medical articles treated with the solution of osmolality increasing compounds according to the method above also relate to the invention.

대표청구항 ▼

A method of forming an improved hydrophilic coating on a substrate, comprising: (a) applying a non-reactive hydrophilic polymer layer to the substrate; (b) applying to the non-reactive hydrophilic polymer layer a solution comprising a solvent and at least 2% (weight per volume) of an osmolality-incr

A method of forming an improved hydrophilic coating on a substrate, comprising: (a) applying a non-reactive hydrophilic polymer layer to the substrate; (b) applying to the non-reactive hydrophilic polymer layer a solution comprising a solvent and at least 2% (weight per volume) of an osmolality-increasing compound selected from the group consisting of mono and disaccharides, sugar alcohols, and non-toxic organic and inorganic salts, with the proviso that the osmolality-increasing compound is not a trihalogenide; and (c) evaporating the solvent.