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Monolithic user-activated transdermal therapeutic system 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61F-013/00
출원번호 US-0231633 (1988-08-10)
발명자 / 주소
  • Heiber Werner (Bedford Hills NY) Andriola Robert (Putnam Valley NY) Williams Paul (Fairlawn NJ) Ebert Charles (Redwood City CA)
출원인 / 주소
  • Ciba-Geigy Corporation (Ardsley NY 02)
인용정보 피인용 횟수 : 71  인용 특허 : 13

초록 ▼

A transdermal drug delivery system which is manufactured in a pre-activated state for at least one of storage stability, manufacture safety, user safety, or control of release characteristic considerations and which is activated by a patient (or other person applying the system to the patient) just

대표청구항 ▼

A monolithic therapeutic substance non-releasing drug delivery system having a removable protective layer thereon, said system comprising (a) a monolithic therapeutic substance reservoir containing a therapeutic agent or precursor of said therapeutic agent in a first form which cannot permeate from

이 특허에 인용된 특허 (13)

  1. Theeuwes Felix (Los Altos CA), Dispenser with diffuser.
    상세보기
  2. Larkin Mark E. (Lindenhurst IL), I.V. fluid storage and mixing system.
    상세보기
  3. Bremer Roger E. (Fort Lee NJ) Anthony ; Jr. Charles (Livingston NJ) Chappel Raymond M. (Mendham NJ), Long-life biomedical application device, particularly electrode, and method of transferring electrical current.
    상세보기
  4. Bremer Roger E. (5 Horizon Rd. Fort Lee NJ 07024) Anthony ; Jr. Charles (53 Hickory Pl. Livingston NJ 07039) Chappel Raymond M. (21 Florie Farm Rd. Mendham NJ 07945), Long-life biomedical transcutaneous drug application device and method of transcutaneous application of drugs.
    상세보기
  5. Andriola Robert (Putnam Valley NY) Moore Donald J. (Pomona NY) Asche Henning (Bettingen CHX), Multicompartmentalized transdermal patches.
    상세보기
  6. Cortese Richard (San Jose CA) Barclay Brian (Menlo Park CA) Theeuwes Felix (Los Altos CA), Simultaneous delivery of two drugs from unit delivery device.
    상세보기
  7. Smith Dwight (Harbor City CA), Stencilling device.
    상세보기
  8. Pailin Eric (43 Park Mount Drive Macclesfield ; Cheshire GB2 SK11 8TM), Topical dressings.
    상세보기
  9. Etscorn Frank T. (121 Stallion Cir. Socorro NM 87801), Transcutaneous application of nicotine.
    상세보기
  10. Gale Robert M. (Los Altos CA) Enscore David J. (Sunnyvale CA), Transdermal delivery of highly ionized fat insoluble drugs.
    상세보기
  11. Lee Eun S. (Redwood City CA) Yum Su I. (Los Altos CA), Transdermal drug delivery device.
    상세보기
  12. Ennis ; III James F. (Preston CT), Two compartment mixing syringe.
    상세보기
  13. Gilman Thomas (Palatine IL), Wound dressing.
    상세보기

이 특허를 인용한 특허 (71)

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  3. Zhang Jie ; Zhang Hao, Apparatus for heating to a desired temperature for improved administration of pharmaceutically active compounds.
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  8. Kanios, David P.; Hartwig, Rod; Mantelle, Juan A.; Houze, David W., Compositions and methods for controlling drug loss and delivery in transdermal drug delivery systems.
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  11. Faucher, Keith M.; Tang, Hui; Ferraro, Joseph; Martakos, Paul; Herweck, Steve A.; Karwoski, Theodore; Corbeil, Scott E., Cross-linked fatty acid-based biomaterials.
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  13. Faucher, Keith M.; Tang, Hui; Martakos, Paul; Karwoski, Theodore; Sullivan, Allison; Melville, Greg; Corbeil, Scott E., Cross-linked fatty acid-based biomaterials.
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  14. Labrecque, Roger; McNamara, Philip; Ferraro, Joseph; Rogers, Lisa; Martakos, Paul; Karwoski, Theodore; Herweck, Steve A.; Faucher, Keith M.; Swanick, Thomas M., Cured gel and method of making.
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  15. Faucher, Keith M.; Conroy, Suzanne; Albergo, Theresa K.; Bienkiewicz, Joseph, Cured oil-hydrogel biomaterial compositions for controlled drug delivery.
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  16. Labrecque, Roger; Moodie, Geoffrey; Ferraro, Joseph; Rogers, Lisa; Martakos, Paul; Karwoski, Theodore; Herweck, Steve A., Drug delivery coating for use with a stent.
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  17. Zhang, Jie; Zhang, Hao, Electrical apparatus for heating to a desired temperature for improved administration of pharmaceutically active compounds.
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  18. Swanick, Thomas M.; Ferraro, Joseph; Rogers, Lisa; Martakos, Paul, Fatty-acid based particles.
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  19. Sriwongjanya,Mongkol; Yuk,Samuel; Nangia,Avinash, Formulation and process for drug loaded cores.
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  20. Zhang, Jie; Lippert, Robert, Heat assisted lidocaine and tetracaine for transdermal analgesia.
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  21. Labrecque, Roger; McNamara, Philip; Ferraro, Joseph; Rogers, Lisa; Martakos, Paul; Karwoski, Theodore; Herweck, Steve A.; Faucher, Keith M.; Swanick, Thomas M., Heat cured gel and method of making.
    상세보기
  22. Faucher, Keith M.; Tang, Hui; Rogers, Lisa; Ferraro, Joseph; Martakos, Paul; Herweck, Steve A.; Karwoski, Theodore, Hydrophobic cross-linked gels for bioabsorbable drug carrier coatings.
    상세보기
  23. Faucher, Keith M.; Tang, Hui; Rogers, Lisa; Ferraro, Joseph; Martakos, Paul; Herweck, Steve A.; Karwoski, Theodore, Hydrophobic cross-linked gels for bioabsorbable drug carrier coatings.
    상세보기
  24. Herweck, Steve A.; Ferraro, Joseph; Martakos, Paul; Karwoski, Theodore; Horton, Anthony Richard, Implantable barrier device.
    상세보기
  25. Hildebrand Keith R. ; Fowler Jan Ellen O. ; Levius Dezso K., Incontinence treatment.
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  26. Zhang, Jie; Zhang, Hao; Hull, Wade A.; Rigby, Larry, Integrated apparatus for controlled heat aided dermal drug delivery.
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  27. Krinke, Todd A., Iontophoretic drug delivery packaging.
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  28. Fish,Jeffrey E.; Brunner,Michael S.; Agarwal,Naveen; Folkenberg,Laura, Laminate structures containing activatable materials.
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  29. Hyatt Gary F. ; Bostic William M., Medical applicator and method.
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  30. Hadvary, Paul; Tschirky, Hansjorg, Medical device adhering to the skin.
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  31. Corbeil, Scott E.; Labrecque, Roger; Martakos, Paul; Karwoski, Theodore; Herweck, Steve A.; Conroy, Suzanne; Sunter, Brian; Bromander, Edward; Henrich, Georgette, Method and apparatus for application of a fresh coating on a medical device.
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  32. Zhang, Jie; Zhang, Hao, Method and apparatus for improved heat controlled administration of pharmaceuticals.
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  33. Jie Zhang ; Hao Zhang, Method for facilitating absorption of pharmaceutically active compounds.
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  34. Green Philip G. (Cliffside Park NJ) Clark Ronald J. (Hewitt NJ) Broberg Bernt Fredrik Julius (Trosa SEX), Method for forming and packaging iontophoretic drug delivery patches and the like to increase stability and shelf-life.
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  35. Jie Zhang ; Hao Zhang ; Larry Rigby ; Wade A. Hull, Method for manufacturing a heat generating apparatus.
    상세보기
  36. Jie Zhang ; Hao Zhang, Method for reducing onset time of pharmaceutically active compounds.
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  37. Caldwell Larry J. (4146 Cranford Cir. San Jose CA 95124) Galer Bradley Stuart (7409 Woodlawn Ave. NE Seattle WA 98115), Method for treating headache pain with topical local anesthetic compositions.
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  38. Galer Bradley S. ; Caldwell Larry J., Method of treating neuroma pain.
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  40. Zhang Jie ; Zhang Hao, Methods and apparatus for improved administration of fentanyl and sufentanil.
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  43. Zhang, Jie; Zhang, Hao; Hull, Wade A.; Rigby, Larry, Methods and apparatus for improved administration of testosterone pharmaceuticals.
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  46. Strauss, Robert C., Multi-layer transdermal drug delivery device.
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  50. Wick John Joachim, Patch applicator.
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  59. Stanley Theodore ; Hull Wade ; Rigby Larry, Transdermal drug patch with attached pocket for controlled heating device.
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  60. Theodore Stanley ; Wade Hull ; Larry Rigby ; Jie Zhang, Transdermal drug patch with attached pocket for controlled heating device.
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  61. Mantelle, Juan, Transdermal estrogen device and delivery.
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