초록 ▼

A process and compositions for reducing post-surgical adhesion formation/reformation in mammals following surgical injury to the peritoneal or pleural cavity or organs situated therein. Both aqueous and non-aqueous compositions comprising a polyoxyalkylene block copolymer are applied to injured area

A process and compositions for reducing post-surgical adhesion formation/reformation in mammals following surgical injury to the peritoneal or pleural cavity or organs situated therein. Both aqueous and non-aqueous compositions comprising a polyoxyalkylene block copolymer are applied to injured areas of the peritoneal or pleural cavity or organs situated therein subsequent to surgical injury.

대표청구항 ▼

A process for reducing post-surgical adhesion formation/reformation following surgical injury to organs situated in the mammalian peritoneal or pleural cavity, comprising separating said organs from adjacent tissue with an effective amount of a composition comprising: a polyoxyalkylene block copolym

A process for reducing post-surgical adhesion formation/reformation following surgical injury to organs situated in the mammalian peritoneal or pleural cavity, comprising separating said organs from adjacent tissue with an effective amount of a composition comprising: a polyoxyalkylene block copolymer of the formula Y[(A)n－E－H]x (I) wherein A is an oxyalkylene moiety having an oxygen/carbon atom ratio of less than 0.5, x is at least 1, Y is derived from water or an organic compound containing x reactive hydrogen atoms, E is a polyoxyethylene moiety, n has a value such that the average molecular weight of A is at least about 500 to about 900, as determined by the hydroxyl number of an intermediate, Y[(A)n－H]x (II) and the total average molecular weight of the copolymer is at least 5000.