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Methods for selectively reacting ligands immobilized within a temperature-sensitive polymer gel 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • G01N-033/00
  • G01N-033/543
출원번호 US-0948377 (1986-12-31)
발명자 / 주소
  • Hoffman Allan S. (Seattle WA) Monji Nobuo (Seattle WA)
출원인 / 주소
  • Genetec Systems Corporation (Seattle WA 02)
인용정보 피인용 횟수 : 43  인용 특허 : 8

초록

Methods for delivering substances into, removing substances from, or reacting substances with a selected environment utilizing polymer gels or coatings characterized by a critical solution temperature (CST) are disclosed. The CST as well as the pore structure, pore size, pore distribution, and absor

대표청구항

A method for separating a desired substance from a solution, comprising: introducing a polymer gel, that is characterized by a critical solution temperature and having immobilized therein a binding component that is the binding partner of said desired substance, into a solution containing said desir

이 특허에 인용된 특허 (8)

  1. Hudgin Donald Edward (Princeton Junction NJ) Blair Edgar Allan (Cranbury NJ), Hydrophilic or hydrogel carrier systems such as coatings, body implants and other articles.
  2. Sharma Yash (2766 January Cts. Falls Church VA 22043), Immunoassay with solid phase having coating containing blood platelet substitute.
  3. Lossef Steven V. (125-15 Cronston Ave. Belle Harbor NY 11694), Insulin delivery device.
  4. Thomas Elaine K. (Seattle WA) Schwartz Dennis E. (Redmond WA) Priest John H. (Everett WA) Nowinski Robert C. (Seattle WA) Hoffman Allan S. (Seattle WA), Polymerization-induced separation assay using recognition pairs.
  5. Nowinski Robert C. (King County WA) Hoffman Allan S. (King County WA), Polymerization-induced separation immunoassays.
  6. Marshall David L. (Carmel IN), Soluble insoluble polymers in enzymeimmunoassay.
  7. Monji Nobuo (Seattle WA) Hoffman Allan S. (Seattle WA) Priest John H. (Everett WA) Houghton Raymond L. (Kirkland WA), Thermally induced phase separation immunoassay.
  8. Kraemer ; Dieter ; Lehmann ; Klaus ; Pennewiss ; Horst ; Plainer ; Herma nn ; Schweder ; Roland, Water-swellable, bead copolymer.

이 특허를 인용한 특허 (43)

  1. Angelici Robert J. ; Gao Hanrong, Catalyst system comprising a first catalyst system tethered to a supported catalyst.
  2. Blahut, Eric, Cell and tissue culture container.
  3. Smith, R. Lane; Tarrant, Laurence J. B.; Kusanagi, Akihiko; Claesson, Hans P. I., Cell-support matrix having narrowly defined uniformly vertically and non-randomly organized porosity and pore density and a method for preparation thereof.
  4. Collins, Gregory Earl; Rose-Pehrsson, Susan L., Chemiluminescence chemical detection of vapors and device therefor.
  5. Claesson, Hans Peter Ingemar; Tarrant, Laurence J. B.; Smith, Robert Lane; Shortkroff, Sonya, Double-structured tissue implant and a method for preparation and use thereof.
  6. Alcantar, Norma A.; Falahat, Rana; Wiranowska, Marzenna; Toomey, Ryan G., Enhanced targeted drug delivery system via chitosan hydrogel and chlorotoxin.
  7. Backlund Sune,FIX ; Eriksson Folke,FIX ; Hedstrom Gun,FIX ; Karlsson Stefan,FIX, Enzyme immobilization in a gel containing 30 to 50 percent gelatin.
  8. Nelson Alan M. ; Pawlak Jan W. ; Pronovost Allan D., Enzyme substrate delivery and product registration in one step enzyme immunoassays.
  9. Nelson, Alan M.; Pawlak, Jan W.; Pronovost, Allan D., Enzyme substrate delivery and product registration in one step enzyme immunoassays.
  10. Rostro, Bertha Catalina; Barrera, Enrique V., Gelled nanotube-containing heat transfer medium.
  11. Um, Pil-Je; Pohl, Christopher A., Hydrophobic surface chip.
  12. Furukawa,Hirotaka; Ohnishi,Noriyuki; Kataoka,Kazunori; Ueno,Katsuhiko, Magnetic fine particles and process for producing the same.
  13. Peters ; Jr. Donald F. (Campbell CA) Dumont Lawrence C. (Santa Cruz CA), Mass producible biologically active solid phase devices.
  14. Poustka, Annemarie; Breitling, Frank; Gross, Karl-Heinz; Dübel, Stefan; Saffrich, Rainer, Method and devices for applying substances to a support, especially monomers for the combinatorial synthesis of molecule libraries.
  15. Ribault, Sebastien; Waiche, Gael, Method and unit for preparing a sample for the microbiological analysis of a liquid.
  16. Ribault, Sebastien; Waiche, Gael, Method and unit for preparing a sample for the microbiological analysis of a liquid.
  17. Shortkroff, Sonya; Khoury, Joseph; Tarrant, Laurence J. B.; Claesson, Hans P. I.; Smith, Robert Lane, Method for improvement of differentiation of mesenchymal stem cells using a double-structured tissue implant.
  18. Mizuno, Shuichi; Kusanagi, Akihiko; Tarrant, Laurence J. B.; Tokuno, Toshimasa; Smith, Robert Lane, Method for preparation of implantable constructs.
  19. Wu Chi,HKX ; Jiang Suhong,HKX, Method for repairing blood vessel system.
  20. Shortkroff, Sonya; Tarrant, Laurence J. B.; Roos, Eric J.; Smith, Robert Lane; Claesson, Hans P. I., Method for use of a double-structured tissue implant for treatment of tissue defects.
  21. Fernandez Julio M. ; Knudson Mark B., Method of delivering a lipid-coated condensed-phase microparticle composition.
  22. Ershov Gennady Moiseevich,RUX ; Mirzabekov Andrei Darievich,RUX, Method of manufacturing a matrix for the detection of mismatches.
  23. Indriksons Andris ; Andrews Patricia C., Methods and apparatus using hydrogels.
  24. Cros, Philippe; Elaissari, Abdelhamid; Mabilat, Claude; Pichot, Christian; Rodrigue, Marc; Santoro, Lise, Nucleic acid isolation.
  25. Stewart, Ray F., Phase change sensor.
  26. Wu Chi,HKX ; Jiang Suhong,HKX, Polymer gel composition and uses therefor.
  27. Leon, Jeffrey W.; Qiao, Tiecheng A.; Mccovick, Robert E., Polymer microspheres containing latent colorants and method of preparation.
  28. Leon,Jeffrey W.; Qiao,Tiecheng A.; Mccovick,Robert E., Polymer microspheres containing latent colorants and method of preparation.
  29. Moya, Wilson, Purification of proteins.
  30. Moya, Wilson; Jaber, Jad, Purification of proteins.
  31. Moya, Wilson; Jaber, Jad, Purification of proteins.
  32. Moya, Wilson; Jaber, Jad, Purification of proteins.
  33. Moya, Wilson; Jaber, Jad, Purification of proteins.
  34. Moya, Wilson; Jaber, Jad, Purification of proteins.
  35. Jaber, Jad; Moya, Wilson; Hamzik, James; Boudif, Arezki; Zhang, Yu; Soice, Neil; Charkoudian, John; Singh, Nripen, Stimulus responsive polymers for the purification of biomolecules.
  36. Jaber, Jad; Moya, Wilson; Hamzik, James; Boudif, Arezki; Zhang, Yu; Soice, Neil; Charkoudian, John; Singh, Nripen, Stimulus responsive polymers for the purification of biomolecules.
  37. Jaber, Jad; Moya, Wilson; Hamzik, James; Boudif, Arezki; Zhang, Yu; Soice, Neil; Charkoudian, John; Singh, Nripen, Stimulus responsive polymers for the purification of biomolecules.
  38. Kelly, Jr., James E.; Muldoon, Joseph William; Proulx, Stephen; Vigna, James, Stirred tank bioreactor.
  39. Moya, Wilson; Dupont, Alison, Stirred tank reactor and method.
  40. Hu, Zhibing; Zhou, Jun; Cai, Tong; Tang, Shijun; Marquez, Manuel, Synthesis of columnar hydrogel colloidal crystals in water-organic solvent mixture.
  41. Hu,Zhibing; Lu,Xihua; Gao,Jun; Cai,Tong; Huang,Gang; Zhou,Bo, Synthesis, uses and compositions of crystal hydrogels.
  42. Mizuno, Shuichi; Kusanagi, Akihiko; Tarrant, Laurence J. B.; Tokuno, Toshimasa; Smith, Robert Lane, Systems for cartilage repair.
  43. McBride,James F.; Gehrke,Stevin H.; Fisher,John P., Temperature controlled solute delivery system.
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