초록 ▼

This invention sets forth an agent for filling bone and tooth defects, for building up bone, for bone-contact layers and for the replacement of bones and the roots of teeth, which contains calcium phosphate apatite having carbonate and alkali portions, all ions being definedly integrated in the crys

This invention sets forth an agent for filling bone and tooth defects, for building up bone, for bone-contact layers and for the replacement of bones and the roots of teeth, which contains calcium phosphate apatite having carbonate and alkali portions, all ions being definedly integrated in the crystal lattice; use is optionally made together with additives and/or diluents both tolerated by the body. Furthermore, it sets forth the use of this apatite for filling bone and tooth defects, for building up bone, for bone-contact layers, as a replacement for bones and the roots of teeth and as an implant article consisting completely or partially of this apatite or consisting of a material known for implant articles and being coated completely or partially with a layer of this apatite.

대표청구항 ▼

An agent for filling bone defects, for building up bone, for forming bone-contact layers on the replacements of bones and roots of teeth and for making independent smaller bone replacement parts or implant articles, comprising a calcium phosphate apatite having carbonate and alkali portions, all ion

An agent for filling bone defects, for building up bone, for forming bone-contact layers on the replacements of bones and roots of teeth and for making independent smaller bone replacement parts or implant articles, comprising a calcium phosphate apatite having carbonate and alkali portions, all ions being definedly integrated in the crystal lattice, of the following formula: Ca10-a-b-xMeIIaMeIb(PO4)6-x(CO3)x(OH)2-b-x(H2O)w wherein MeI is a singly charged metal ion, MeII is a doubly charged metal ion, a represents the number of double charged metal ions with the exception of Ca and is a value from 0 to 1.0, b represents the number of singly charged metal ions and is a value from 0.05 to 1.2, x represents the number of carbonate ions and is a value from 0.02 to 1.2, the sum b+x being a maximum of 2.0, and w represents the number of water molecules integrated in the crystal lattice and is a value from 0 to b+x wherein at least a portion of the MeI ions are alkali ions and the CO3 ions are positioned at the PO4 positions within the apatite lattice.