초록 ▼

A hollow fiber membrane type oxygenator is provided wherein a bundle of a plurality of hollow porous fibers presenting gas exchange membranes axially extends through a housing to define a first flow path for oxygen, a pair of partitions support the opposed open ends of the hollow fibers to isolate t

A hollow fiber membrane type oxygenator is provided wherein a bundle of a plurality of hollow porous fibers presenting gas exchange membranes axially extends through a housing to define a first flow path for oxygen, a pair of partitions support the opposed open ends of the hollow fibers to isolate the open ends from the first flow path to define a second flow path through the fiber cavities for blood, and the micropores in the hollow fibers are filled with a silicone compound, for exmaple, a RTV silicone rubber or a blend thereof with a silicone oil while the hollow fibers on their side wall are substantially free of a layer of the silicone compound. The oxygenator is manufactured by prefabricating an oxygenator module of the above-mentioned construction, impregnating the hollow fibers with a solution of the silicone compound, and passing a cleaning liquid to remove excessive silicone compound, thereby filling only the micropores with the silicone compound.

대표청구항 ▼

A hollow fiber membrane type oxygenator comprising a housing, a bundle of a plurality of gas-exchange hollow fiber membranes axially extending through the housing, a first fluid chamber defined by the outer surface of said hollow fibers and the inner surface of said housing, a first fluid inlet and

A hollow fiber membrane type oxygenator comprising a housing, a bundle of a plurality of gas-exchange hollow fiber membranes axially extending through the housing, a first fluid chamber defined by the outer surface of said hollow fibers and the inner surface of said housing, a first fluid inlet and a first fluid outlet both in fluid communication with said first fluid chamber, a partition supporting either end of said hollow fibers and isolating the fiber end from said first fluid chamber, and a second fluid inlet and a second fluid outlet both in fluid communication with the interior space of said hollow fibers, characterized in that each said hollow fiber membrane has a plurality of micropores extending throughout the membrane, the micropores are substantially filled with a silicone blend comprising a silicone rubber and a silicone oil, but the hollow fiber membrane is free of a layer of said silicone blend on each of its internal and external walls of more than 500 Å.