초록

This invention pertains to a programmable delivery system.

대표청구항 ▼

A delivery system for delivering a beneficial drug at a controlled rate to a biological environment, wherein the delivery system comprises: (a) a reservoir dimensioned for use and retention in the biological environment, the reservoir comprising a polymeric formulation that permits the passage of dr

A delivery system for delivering a beneficial drug at a controlled rate to a biological environment, wherein the delivery system comprises: (a) a reservoir dimensioned for use and retention in the biological environment, the reservoir comprising a polymeric formulation that permits the passage of drug; (b) a beneficial drug in the reservoir; (c) a first membrane in contacting relation with a surface of the reservoir, the membrane comprising a material substantially impermeable to the passage of an osmagent; (d) an osmagent in the first membrane in contacting relation with a surface of the reservoir; (e) a second membrane in contact with a different surface of the reservoir, the second membrane comprising a material substantially impermeable to the passage of an osmagent; and (f) an osmagent in the second membrane in contacting relation with a different surface of the reservoir, and wherein, when the delivery system is in operation in the biological environment, beneficial drug is released by the formation of osmotically-bursting apertures in (c) and (e).