$\require{mediawiki-texvc}$
  • 검색어에 아래의 연산자를 사용하시면 더 정확한 검색결과를 얻을 수 있습니다.
  • 검색연산자
검색도움말
검색연산자 기능 검색시 예
() 우선순위가 가장 높은 연산자 예1) (나노 (기계 | machine))
공백 두 개의 검색어(식)을 모두 포함하고 있는 문서 검색 예1) (나노 기계)
예2) 나노 장영실
| 두 개의 검색어(식) 중 하나 이상 포함하고 있는 문서 검색 예1) (줄기세포 | 면역)
예2) 줄기세포 | 장영실
! NOT 이후에 있는 검색어가 포함된 문서는 제외 예1) (황금 !백금)
예2) !image
* 검색어의 *란에 0개 이상의 임의의 문자가 포함된 문서 검색 예) semi*
"" 따옴표 내의 구문과 완전히 일치하는 문서만 검색 예) "Transform and Quantization"

통합검색

도움말도움말
상세검색 다국어 입력

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

특허 상세정보

MyON담기
내보내기 페이스북 공유 카카오톡 공유

Sustained release formulation containing an ion-exchange resin

특허상세정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판) A01N-025/26    A61J-003/10    A61K-031/74    C08F-008/00   
미국특허분류(USC) 424/427 ; 424/429 ; 424/78 ; 424/79
출원번호 US-0224199 (1988-07-21)
발명자 / 주소
  • Bawa Rajan (Fairport NY) Ruscio Dominic V. (Rochester NY)
출원인 / 주소
  • Bausch & Lomb Incorporated (Rochester NY 02)
인용정보 피인용 횟수 : 84  인용 특허 : 13
초록

A sustained-release polymeric hydrogel dosage form useful for topical, systemic or transdermal administration of a medicinal agent comprising a cross-linked, polymerized hydrophilic polymer, an ion-exchange resin, a cross-linking agent, an optical hydrophobic polymer and said medicinal agent in a therapeutically effective amount.

대표
청구항

A sustained-release polymeric hydrogel dosage form useful for topical, systemic or transdermal administration of a medicinal agent comprising 50% to 90% w/w of a cross-linked, polymerized hydrophilic polymer, 0.1% to 35% w/w of an ion-exchange resin, which was mixed with the monomer used to form said polymerized hydrophilic monomer prior to polymerization, 0.1% to 20% w/w of a cross-linking agent and said medicinal agent in a therapeutically effective amount.

인용문헌 (13)

  1. Robinson Joseph R. (Madison WI), Bioadhesive compositions and methods of treatment therewith.
  2. Higuchi Takeru (Lawrence KS) Hussain Anwar (Lexington KY), Device consisting of copolymer having acetoxy groups for delivering drugs.
  3. Mamajek Ronald C. (Glenside PA) Moyer Ernest S. (Grafton WV), Drug-dispensing device and method.
  4. Fields, Joseph E.; Johnson, John H., Method for controlling blood triglycerides.
  5. Leopold ; Irving H., Method of treatment for glaucoma.
  6. Samejima Masayoshi (Minoh JPX) Hirata Goichi (Yawata JPX) Koida Yoshiyuki (Katano JPX) Kobayashi Yoshinori (Toyonaka JPX) Kida Akira (Settsu JPX), Microcapsules and method of preparing same.
  7. Chiou George C. Y. (College Station TX) Liu Hsin-Kuang (Boston MA), Ophthalmic compositions and their use for treating elevated intraocular pressure and glaucoma.
  8. Chromecek Richard C. (Goshen CT), Polymer complex carriers for an active ingredient.
  9. Rankin Billy F. (Rockville MD), Polystyrene sulfonate containing opthalmic solutions.
  10. Michaels Alan S. (Atherton CA), Structured bioerodible drug delivery device.
  11. Schoenwald Ronald D. (Fort Worth TX) Roehrs Robert E. (Fort Worth TX), Sustained release ophthalmic drug dosage.
  12. Schoenwald Ronald D. (Fort Worth TX) Roehrs Robert E. (Fort Worth TX), Sustained release ophthalmic drug dosage.
  13. Cohen Arthur I. (Rochester NY) Sim James S. Y. (Rochester NY) Van Horn Maurice H. (Rochester NY) Gordesky Stanley E. (Rochester NY) Gordon Stanley I. (Rochester NY), Sustained release pharmaceutical composition.

이 특허를 인용한 특허 (84)

  1. Moscona, Anne; Porotto, Matteo; LaVan, David Alexander; Yi, Feng, Anti-viral method.
  2. Margolis, David; Bowe, Whitney, Bacterial-derived BLIS for treatment of acne.
  3. Pfahl,Magnus; Tachdjian,Catherine; Al Shamma,Hussien A.; Giachino,Andrea Fanjul; Jakubowicz Jaillardon,Karine; Guo,Jianhua; Fine,Richard M.; Spruce,Lyle W.; Zapf,James W., Bicyclic heterocycles for the treatment of diabetes and other diseases.
  4. Chen, Guohua; Houston, Paul R.; Kleiner, Lothar; Spaltro, John, Catheter injectable depot compositions and uses thereof.
  5. Hubbell, Jeffrey A.; Pathak, Chandrashekhar P.; Sawhney, Amarpreet S.; Desai, Neil P.; Hill, Jennifer L.; Hossainy, Syed F. A., Coating substrates by polymerizing macromers having free radical-polymerizable substituents.
  6. Gadek, Thomas; Burnier, John, Compositions and methods for treatment.
  7. Gadek, Thomas; Burnier, John; Zhong, Min; Shen, Wang; Oslob, Johan D.; Barr, Kenneth, Compositions and methods for treatment.
  8. Oslob, Johan; Shen, Wang; Barr, Kenneth; Zhong, Min, Compositions and methods for treatment.
  9. Oslob, Johan; Shen, Wang; Barr, Kenneth; Zhong, Min, Compositions and methods for treatment.
  10. Zhong, Min; Shen, Wang; Oslob, Johan D.; Barr, Kenneth, Compositions and methods for treatment.
  11. Zhong, Min; Shen, Wang; Oslob, Johan D.; Barr, Kenneth, Compositions and methods for treatment.
  12. Gadek, Thomas; Burnier, John, Compositions and methods for treatment of eye disorders.
  13. Tengler, Mark; Taskey, Paul; Lockhart, Daniel; McMahen, Russell, Compositions and methods of making sustained release liquid formulations.
  14. Byrne, Mark E.; Venkatesh, Siddarth, Contact drug delivery system.
  15. Byrne, Mark E.; Venkatesh, Siddarth, Contact drug delivery system.
  16. Cejkova Jitka (102 11 Praha 10 V Novem Hostivati 21 CSX) Vacik Jiri (140 00 Praha 4 Mechanicka 18/2560 CSX), Contact lens of hydrophilic gels with inhibitor and swelling agent.
  17. Ali, Maryam; Byrne, Mark E., Controlled and extended delivery of hyaluronic acid and comfort molecules via a contact lens platform.
  18. Galin Miles A. (180 E. End Ave. New York NY 10128) Salamone Joseph C. (2202 NW. 62nd. Dr. Boca Raton FL 33496) Israel Stanley C. (675 West St. Carlisle MA 01741), Controlled release of miotic and mydriatic drugs in the anterior chamber.
  19. Galin Miles A. ; Salamone Joseph C. ; Israel Stanley C., Controlled release of miotic and mydriatic drugs in the anterior chamber.
  20. Galin Miles A. ; Salamone Joseph C. ; Israel Stanley C., Controlled release of miotic and myriatic drugs in the anterior chamber.
  21. Galin Miles A. ; Salamone Joseph C. ; Israel Stanley C., Controlled release of pharmaceuticals in the anterior chamber of the eye.
  22. Burnier, John, Crystalline pharmaceutical and methods of preparation and use thereof.
  23. Burnier, John, Crystalline pharmaceutical and methods of preparation and use thereof.
  24. Burnier, John, Crystalline pharmaceutical and methods of preparation and use thereof.
  25. Burnier, John, Crystalline pharmaceutical and methods of preparation and use thereof.
  26. Burnier, John; Gadek, Thomas; Naud, Frederic, Crystalline pharmaceutical and methods of preparation and use thereof.
  27. Burnier, John; Gadek, Thomas; Naud, Frederic, Crystalline pharmaceutical and methods of preparation and use thereof.
  28. Schultz, Clyde L.; Schentag, Jerome J., Device and method for the delivery of drugs for the treatment of posterior segment disease.
  29. Venkatesh, Siddarth; Wower, Jacek; Byrne, Mark E., Drug delivery system and method.
  30. Byrne, Mark E.; Venkatesh, Siddarth; White, Charles; Ali, Maryam, Extended or continuous wear silicone hydrogel contact lenses for the extended release of comfort molecules.
  31. Hubbell Jeffrey A. ; Pathak Chandrashekhar P. ; Sawhney Amarpreet S. ; Desai Neil P. ; Hill Jennifer L. ; Hossainy Syed F. A., Gels for encapsulation of biological materials.
  32. Hubbell Jeffrey A. ; Pathak Chandrashekhar P. ; Sawhney Amarpreet S. ; Desai Neil P. ; Hossainy Syed F. A., Gels for encapsulation of biological materials.
  33. Schultz, Clyde L., Growth factor delivery system for the healing of wounds and the prevention of inflammation and disease.
  34. Schultz,Clyde L., Growth factor delivery systems for the healing of wounds and the prevention of inflammation and disease.
  35. Pfahl,Magnus; Tachdjian,Catherine; Al Shamma,Hussien A.; Giachino,Andrea Fanjul; Jakubowicz Jaillardon,Karine; Guo,Jianhua; Boudjelal,Mohamed; Zapf,James W., Heterocyclic amide derivatives for the treatment of diabetes and other diseases.
  36. Pfahl,Magnus; Tachdjian,Catherine; Al Shamma,Hussien A.; Fanjul,Andrea; Pleynet,David P.M.; Spruce,Lyle W.; Wiemann,Torsten R.; Ibarra,Jason B., Heterocyclic derivatives for the treatment of cancer and other proliferative diseases.
  37. Pfahl, Magnus; Tachdjian, Catherine; Al-Shamma, Hussien A.; Fanjul, Andrea; Pleynet, David P. M.; Spruce, Lyle W., Imidazolidinedione derivatives for the treatment of diabetes and other diseases.
  38. Hubbell,Jeffrey A.; Pathak,Chandrashekhar P.; Sawhney,Amarpreet S.; Desai,Neil P.; Hill,Jennifer L.; Hossainy,Syed F. A., Implantable substrate coated with a macromer having free radical polymerizable substituents.
  39. Shapiro, Leland, Inhibitors of serine protease activity and their use in methods and compositions for treatment of viral infections.
  40. Leland Shapiro, Inhibitors of serine protease activity, methods and compositions for treatment of nitric-oxide-induced clinical conditions.
  41. Chen, Guohua; Houston, Paul R.; Kleiner, Lothar Walter; Spaltro, John J., Injectable depot compositions and uses thereof.
  42. Chen, Guohua; Houston, Paul; Kleiner, Lothar; Wright, Jeremy, Injectable multimodal polymer depot compositions and uses thereof.
  43. Zeller, James Robert; Venkatraman, Sripathy; Brot, Elisabeth C. A.; Iyer, Subashree; Hall, Michael, LFA-1 inhibitor and methods of preparation and polymorph thereof.
  44. Zeller, James Robert; Venkatraman, Sripathy; Brot, Elisabeth C. A.; Iyer, Subashree; Hall, Michael, LFA-1 inhibitor and methods of preparation and polymorph thereof.
  45. Saffran, Bruce N., Medical devices and methods for modulation of physiology using device-based surface chemistry.
  46. Crooks, Peter A.; Jordan, Craig T.; Pei, Shanshan; Nasim, Shama, Melampomagnolide B derivatives as antileukemic and cytotoxic agents.
  47. Webel, Stephen K.; Swanson, Mark E., Method and composition for synchronizing time of insemination.
  48. Webel, Stephen K.; Swanson, Mark E., Method and composition for synchronizing time of insemination.
  49. Webel, Stephen Kent; Swanson, Mark E., Method and composition for synchronizing time of insemination.
  50. Webel, Stephen Kent; Swanson, Mark E.; Kraeling, Robert R.; Johnston, Michael E., Method and compositions for synchronizing time of insemination in gilts.
  51. Shen, Wang; Barr, Kenneth; Oslob, Johan D.; Zhong, Min, Modulators of cellular adhesion.
  52. Shen, Wang; Barr, Kenneth; Oslob, Johan D.; Zhong, Min, Modulators of cellular adhesion.
  53. Pfahl,Magnus; Tachdjian,Catherine; Spruce,Lyle W.; Al Shamma,Hussien A.; Boudjelal,Mohamed; Fanjul,Andrea N.; Wiemann,Torsten R.; Pleynet,David P. M., N-substituted heterocycles for the treatment of hypercholesteremia, dyslipidemia and other metabolic disorders; cancer, and other diseases.
  54. Yoo, Barney; Bradbury, Michelle; Wiesner, Ulrich; Ma, Kai, Nanoparticle drug conjugates.
  55. Keenan Robert M., Nicotine metabolites and human body weight.
  56. Keenan Robert M., Nicotine metabolites and nicotine dependence.
  57. Jungherr Lisa B. ; Ottoboni Thomas B., Ocular microsphere delivery system.
  58. Sato, Takao; Uchida, Rei; Uno, Kenji, Ophthalmic lenses capable of sustained drug release and preservative solutions therefor.
  59. Battaglia, Alex; Beim, Eva, Oral care compositions for topical application.
  60. Mashelkar Raghunath Anant,INX ; Kulkarni Mohan Gopalkrishna,INX ; Karmalkar Rohini Nitin,INX, Polymer composition for controlled release of active ingredients in response to pH, and a process of preparing the same.
  61. Krystyna Plochocka, Polymeric delivery and release systems for oral care actives.
  62. Kaufman, Herbert E., Preparations and methods for ameliorating or reducing presbyopia.
  63. Kaufman, Herbert E., Preparations and methods for ameliorating or reducing presbyopia.
  64. Lauderdale, James W, Process for the synchronization of ovulation for timed breeding without heat detection.
  65. Lauderdale, James W., Process for the synchronization of ovulation for timed breeding without heat detection.
  66. Lauderdale, James W., Process for the synchronization of ovulation for timed breeding without heat detection.
  67. Lauderdale, James W., Process for the synchronization of ovulation for timed breeding without heat detection.
  68. Lauderdale, James W., Process for the synchronization of ovulation for timed breeding without heat detection.
  69. Lauderdale, James W., Process for the synchronization of ovulation for timed breeding without heat detection.
  70. Blaskovich, Mark Arnold Thomas; Baughman, Ted; Little, Thomas; Qabar, Maher; Schultz, Lauri Marie; Hong, Feng; Patt, William; Nagula, Gangadhar; Gage, Jennifer Lynn; Howbert, James Jeffry, Protein tyrosine phosphatase inhibitors and methods of use thereof.
  71. Blaskovich,Mark Arnold Thomas; Baughman,Ted; Little,Thomas; Patt,William; Qabar,Maher; Schultz,Lauri Mario; Nagula,Gangadhar; Gage,Jennifer Lynn; Howbert,James Jeffry, Protein tyrosine phosphatase inhibitors and methods of use thereof.
  72. Tachdjian,Catherine; Jakubowicz Jaillardon,Karine, RXR activating molecules.
  73. Chen, Guohua; Priebe, David, Short duration depot formulations.
  74. Chen, Guohua; Priebe, David T., Short duration depot formulations.
  75. Pfahl,Magnus; Tachdjian,Catherine; Al Shamma,Hussien A.; Fanjul,Andrea; Pleynet,David P. M.; Spruce,Lyle W., Substituted heterocycles for the treatment of diabetes and other diseases.
  76. Byrne, Mark E.; Collins, Allison; Vaughan, Asa D.; Venkatesh, Siddarth, Therapeutic contact lenses with anti-fungal delivery.
  77. Keenan Robert M. (Baltimore MD) Hatsukami Dorothy K. (Golden Valley MN), Therapeutic method to alleviate the craving associated with cessation of tobacco with cotinine.
  78. Pfahl, Magnus; Tachdjian, Catherine; Al-Shamma, Hussien A.; Fanjul, Andrea; Pleynet, David P. M.; Spruce, Lyle W., Thiazolidinedione derivatives for the treatment of diabetes and other diseases.
  79. Kamm, Michael A.; Phillips, Robin K. S., Topical pharmaceutical composition comprising a cholinergic agent or a calcium channel blocker.
  80. Kamm, Michael A.; Phillps, Robin K. S., Topical pharmaceutical composition comprising a cholinergic agent or a calcium channel blocker.
  81. Keenan Robert M., Transdermal nicotine metabolites and human body weight.
  82. Jeffrey A. Hubbell CH; Chandrashekhar P. Pathak ; Amarpreet Sawhney ; Neil Desai ; Syed Hossainy ; Jennifer L. Hill-West, Treating medical conditions by polymerizing macromers to form polymeric materials.
  83. Shukla, Anita; Shukla, Shashank, Tunable anti-microbial loaded hydrogels.
  84. Keenan Robert M. (Baltimore MD) Hatsukami Dorothy K. (Golden Valley MN), Use of cotinine to assist in the cessation of tobacco smoking.

IPC 상위 출원인