초록 ▼

A medical device with an antimicrobial coating that is safe, effective, photostable and readily manufacturable can be produced by applying a composition to at least one body fluid-contacting surface of the device such that a solid coating is provided on that surface, the coating composition comprisi

A medical device with an antimicrobial coating that is safe, effective, photostable and readily manufacturable can be produced by applying a composition to at least one body fluid-contacting surface of the device such that a solid coating is provided on that surface, the coating composition comprising an oligodynamic metal salt of a sulfonylurea, a polymeric material, at least one acid compound selected from the group consisting of a water-soluble carboxylic acid and water-insoluble carboxylic acid, and a carrier liquid in which foregoing components are soluble. The antimicrobial coating accommodates variation in the release of antimicrobial metal ions as a function of the intended use for a medical device to which the coating is applied.

대표청구항 ▼

A medical device comprising (a) a substrate presenting a surface suitable for contact with a body fluid and (b) an antimicrobial coating provided on said surface, said coating comprising an oligodynamic metal salt of a sulfonylurea, a polymeric material and at least one acid compound selected from t

A medical device comprising (a) a substrate presenting a surface suitable for contact with a body fluid and (b) an antimicrobial coating provided on said surface, said coating comprising an oligodynamic metal salt of a sulfonylurea, a polymeric material and at least one acid compound selected from the group consisting of a water-soluble carboxylic acid and a water-insoluble carboxylic acid, said device being suitable for extended contact with a body, of a patient or with body fluids.