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Monoclonal antibodies for interleukin-1b 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • G01N-033/53
출원번호 US-0895003 (1986-08-08)
발명자 / 주소
  • Allison Anthony C. (Belmont CA) Eugui Elsie M. (Belmont CA) Kenney John S. (Palo Alto CA) Masada Marvin P. (Mountain View CA)
출원인 / 주소
  • Syntex (U.S.A.) Inc. (Palo Alto CA 02)
인용정보 피인용 횟수 : 47  인용 특허 : 3

초록

The present invention is concerned with novel monoclonal antibodies which bind to Interleukin-1bbbb

대표청구항 ▼

An immunoassay method for the detection of Interleukin-1bwhich comprises: contacting a sample suspected of containing Interleukin-1bwith a monoclonal antibody that binds to Interleukin-1band does not bind to Interleukin-1athat blocks binding of Interleukin-1bto Interleukin-1 receptors; and, that bin

이 특허에 인용된 특허 (3)

  1. David Gary S. (La Jolla CA) Greene Howard E. (Carlsbad CA), Immunometric assays using monoclonal antibodies.
    상세보기
  2. Hoffmann Michael K. (New York NY), Process for making human antibody producing B-lymphocytes.
    상세보기
  3. Boguslaski Robert C. (Elkhart IN) Carrico Robert J. (Elkhart IN) Christner James E. (Ann Arbor MI), Specific binding assay with an enzyme modulator as a labeling substance.
    상세보기

이 특허를 인용한 특허 (47)

  1. Walsh, Kenneth; Fuster, Jose, Age-associated clonal hematopoiesis accelerates cardio-metabolic disease development.
    상세보기
  2. Bedoucha, Marc; Breuer, Sebastian; Dengl, Stefan; Gassner, Christian; Georges, Guy; Gruener, Sabine; Hartmann, Guido; Huelsmann, Peter Michael; Moelleken, Joerg; Mundigl, Olaf; Regula, Joerg Thomas; Weiser, Barbara, Anti-PDGF-B antibodies and methods of use.
    상세보기
  3. Green, Larry; Faggioni, Raffaella; Foord, Orit; Klakamp, Scott L.; Senaldi, Giorgio; Schneider, Amy K., Antibodies against interleukin-1β.
    상세보기
  4. Boyle,William J.; Martin,Francis H.; Corvalan,Jose R.; Davis,C. Geoffrey, Antibodies to OPGL.
    상세보기
  5. Gram,Hermann; Di Padova,Franco E, Antibodies to human IL-1β.
    상세보기
  6. Gram,Hermann; Di Padova,Franco E., Antibodies to human IL-1β.
    상세보기
  7. Gram, Hermann; Di Padova, Franco E, Antibodies to human IL-1β.
    상세보기
  8. Gram, Hermann; Di Padova, Franco E, Antibodies to human IL-1β.
    상세보기
  9. Lawson, Alastair David Griffiths; Popplewell, Andrew George, Antibody molecules having specificity for human IL-1β.
    상세보기
  10. Adams Steven P. (St. Charles MO) Bulock Joseph W. (St. Peters MO) Fok Kam F. (St. Louis MO), Bioactive fragment of interleukin-1-B that has antagonistic activity.
    상세보기
  11. Auron Philip E. ; Dinarello Charles A. ; Webb Andrew C. ; Rich Alexander ; Wolff ; deceased Sheldon M., Biologically active fragments of IL-1.beta..
    상세보기
  12. Joseph C. Glorioso ; Christopher H. Evans ; Paul D. Robbins ; Richard Kane, Cartilage alterations by administering to joints chondrocytes comprising a heterologous polynucleotide.
    상세보기
  13. Boone, Thomas C.; Hershenson, Susan; Bevilacqua, Michael P.; Collins, David S., Composition and method for treating inflammatory diseases.
    상세보기
  14. Glorioso Joseph C. ; Evans Christopher H. ; Robbins Paul D., Gene transfer for studying and treating a connective tissue of a mammalian host.
    상세보기
  15. Dickinson, Craig Duane; Vasserot, Alain Philippe; Watkins, Jeffry Dean; Lu, Jirong, Humanized anti-IL-1 beta antibodies.
    상세보기
  16. Dickinson, Craig Duane; Vasserot, Alain Philippe; Watkins, Jeffry Dean; Lu, Jirong, Humanized anti-IL-1β antibodies.
    상세보기
  17. Raibekas, Andrei; Kerwin, Bruce, IL-1ra variants.
    상세보기
  18. Masat, Linda; Haak-Frendscho, Mary; Horwitz, Arnold H.; Chen, Gang; Roell, Marina, IL-1β binding antibodies and binding fragments thereof.
    상세보기
  19. Masat, Linda; Haak Frendscho, Mary; Chen, Gang; Horwitz, Arnold; Roell, Marina, IL-1β binding antibodies and fragments thereof.
    상세보기
  20. Masat, Linda; Haak-Frendscho, Mary; Horwitz, Arnold H.; Chen, Gang; Roell, Marina, IL1-β Binding antibodies and fragments thereof.
    상세보기
  21. Glorioso Joseph C. ; Evans Christopher H. ; Robbins Paul D., IRAP gene as treatment for arthritis.
    상세보기
  22. Thompson Robert C. ; Carmichael David F., Method for treating interleukin-1 mediated diseases.
    상세보기
  23. Masat, Linda; Haak-Frendscho, Mary; Horwitz, Arnold H.; Chen, Gang; Roell, Marina, Method of treating an IL-1 related autoimmune disease or condition.
    상세보기
  24. Masat, Linda; Haak-Frendscho, Mary; Horwitz, Arnold H.; Chen, Gang; Roell, Marina, Method of treating an IL-1 related cancer.
    상세보기
  25. Masat, Linda; Haak-Frendscho, Mary; Horwitz, Arnold H.; Chen, Gang; Roell, Marina, Method of treating an IL-1 related coronary condition.
    상세보기
  26. Masat, Linda; Haak-Frendscho, Mary; Chen, Gang; Horwitz, Arnold; Roell, Marina, Method of treating an IL-1 related inflammatory disease or condition.
    상세보기
  27. Lawson, Alastair David Griffiths; Popplewell, Andrew George, Method of treating inflammation by administering human IL-1B antibodies.
    상세보기
  28. Masat, Linda; Haak-Frendscho, Mary; Chen, Gang; Horwitz, Arnold; Roell, Marina, Method of treating inflammatory eye disease with IL-1β binding antibodies.
    상세보기
  29. Masat, Linda; Haak Frendscho, Mary; Chen, Gang; Horwitz, Arnold; Roell, Marina, Method of treating or preventing an IL-1 related disease or condition.
    상세보기
  30. Scannon, Patrick J.; Solinger, Alan M.; Bauer, Robert J., Methods for improvement of beta cell function with anti-IL-1β antibodies or fragments thereof.
    상세보기
  31. Solinger, Alan M.; Gül, Ahmet, Methods for the treatment of IL-1β related conditions.
    상세보기
  32. Solinger, Alan M.; Scannon, Patrick J.; Bauer, Robert J., Methods for the treatment of IL-1β related diseases.
    상세보기
  33. Solinger, Alan M.; Scannon, Patrick J.; Bauer, Robert J., Methods for the treatment of IL-1β related diseases.
    상세보기
  34. Solinger, Alan M.; Scannon, Patrick J.; Bauer, Robert J., Methods for the treatment of IL-1β related diseases.
    상세보기
  35. Solinger, Alan M.; Scannon, Patrick J.; Bauer, Robert J., Methods for the treatment of IL-1β related diseases.
    상세보기
  36. Solinger, Alan M., Methods for the treatment of gout.
    상세보기
  37. Solinger, Alan M.; Gül, Ahmet, Methods for the treatment of uveitis with IL-1β binding antibodies.
    상세보기
  38. Thompson, Robert C.; Hannum, Charles H.; Eisenberg, Stephen P.; Arend, William P.; Joslin, Fenneke G.; Sommer, Andreas, Nucleic acids encoding interleukin-1 inhibitors and processes for preparing interleukin-1 inhibitors.
    상세보기
  39. Masat, Linda; Haak-Frendscho, Mary; Horwitz, Arnold H.; Chen, Gang; Roell, Marina, Pharmaceutical compositions comprising IL-1B binding antibodies and fragments thereof.
    상세보기
  40. Auron Philip E. ; Dinarello Charles A. ; Webb Andrew C. ; Rich Alexander ; Wolff Sheldon M., Recombinant DNA which codes for interleukin-1.
    상세보기
  41. Lisi Peter J., Selective immunoassay for IL-1.beta..
    상세보기
  42. Lisi Peter J., Selective immunoassay for IL-L.beta..
    상세보기
  43. Staats Herman F. ; Haynes Barton F. ; Patel Dhavalkumar D. ; Sempowski Gregory D., Substantially non-toxic biologically active mucosal adjuvants in vertebrate subjects.
    상세보기
  44. Staats,Herman F.; Haynes,Barton F.; Patel,Dhavalkumar D.; Sempowski,Gregory D., Substantially non-toxic biologically active mucosal adjuvants in vertebrate subjects.
    상세보기
  45. Reece Barry T. (London GB2) Rozen Michael G. (Irving TX) Deeds David A. (Dallas TX) Roberts Dale K. (Sanger TX 4), System and method for determining efficacy of sunscreen formulations.
    상세보기
  46. Glorioso Joseph C. ; Evans Christopher H. ; Robbins Paul D. ; Bandara Geethani, Viral vectors to inhibit leukocyte infiltration or cartilage degradation of joints.
    상세보기
  47. Glorioso Joseph C. ; Evans Christopher H. ; Robbins Paul D. ; Ghivizzani Steven C., Viral vectors to inhibit leukocyte infiltration or cartilage degradation of joints.
    상세보기

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