초록 ▼

Agglutination assays, particularly latex agglutination assays, for simultaneous testing for a multiplicity of ligands. The reagents for use in the assays comprise two or more insoluble colored substances, each substance being adapted to form a distinctively colored agglutinate in the presence of a s

Agglutination assays, particularly latex agglutination assays, for simultaneous testing for a multiplicity of ligands. The reagents for use in the assays comprise two or more insoluble colored substances, each substance being adapted to form a distinctively colored agglutinate in the presence of a specific ligand or specific group of ligands.

대표청구항 ▼

A method of testing for the presence of two ligands in an aqueous liquid medium comprising the steps of: A. mixing a sample of the said medium with a reagent comprising a mixture of polymer latex particles collectively of two colors, the particles of the first of said two colors having attached ther

A method of testing for the presence of two ligands in an aqueous liquid medium comprising the steps of: A. mixing a sample of the said medium with a reagent comprising a mixture of polymer latex particles collectively of two colors, the particles of the first of said two colors having attached thereto antibody selectively bindable to the first of said two ligands and the particles of the second of said two colors having attached thereto antibody selectively bindable to the second of said two ligands, whereby the presence of the first of said two ligands in the sample is indicated by the selective agglutination of the particles having attached thereto the antibody selectively bindable to the first of said two ligands and the presence of the second of said two ligands in the sample is indicated by the selective agglutination of the particles having attached thereto the antibody selectively bindable to the second of said two ligands; B. after an appropriate period of time, inspecting the mixture resulting from step A; and C. determining the presence of two ligands from the appearance of said mixture. A test reagent for determining the presence of two ligands in a sample of an aqueous liquid medium which comprises a mixture of polymer latex particles collectively of two colors, the particles of the first of said two colors having attached thereto antibody selectively bindable to the first of said two ligands and the particles of the second of said two colors having attached thereto antibody selectively bindable to the second of said two ligands, whereby the presence of the first of said two ligands in the sample is indicated by the selective agglutination of the particles having attached thereto the antibody selectively bindable to the first of said two ligands and the presence of the second of said two ligands in the sample is indicated by the selective agglutination of the particles having attached thereto the antibody selectively bindable to the second of said two ligands.