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Method of identity analyte-binding peptides 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • B01D-015/08
출원번호 US-0355042 (1989-05-16)
발명자 / 주소
  • Kauvar Lawrence M. (San Francisco CA)
출원인 / 주소
  • Terrapin Technologies, Inc. (San Francisco CA 02)
인용정보 피인용 횟수 : 53  인용 특허 : 10

초록

A method for affinity chromatography or adsorption of a designated analyte utilizes a paralog as the affinity partner. The immobilized paralog can be used in purification or analysis of the analyte; the paralog can also be used as a substitute for antibody in an immunoassay. The paralog is identifie

대표청구항

A method to identify a peptide having a sequence of 4-20 amino acids useful for the conduct of affinity chromatography with respect to an analyte, wherein said peptide has specific affinity for said analyte, which method comprises: screening, for ability to bind said analyte, a panel of individual c

이 특허에 인용된 특허 (10)

  1. Ayers John S. (Palmerston North NZX) Bethell Geoffrey S. (Palmerston North NZX) Hancock William S. (Palmerston North NZX) Hearn Milton T. W. (Dunedin North NZX), Activated matrix and method of activation.
  2. Kiniwa Hideaki (Yokohama JPX), Adsorbent.
  3. Cuatrecasas ; Pedro ; Parikh ; Indu, Affinity chromatography of vibrio cholerae enterotoxin-ganglioside polysaccharide and the biological effects of ganglio.
  4. Sderberg John L. (Upsala SEX), Ampholyte and its use in separation processes.
  5. Pinkerton, Thomas C.; Hagestam, Helene I., Chromatographic method and means.
  6. Pollard ; Jr. John K. (Del Mar CA), Material and method for removing immunoglobulins from whole blood.
  7. Degen Peter J. (Huntington NY) Martin Jerold (Plainview NY) Schriefer Judy (Commack NY) Shirley Brenda (Athens GA), Methods of concentrating ligands and active membranes used therefor.
  8. Hou Kenneth C. (14 Hunting Ridge Rd. S. Glastonbury CT 06073) Liao Tung-Ping D. (109 Vernwood Dr. Vernon CT 06066), Modified polysaccharide supports.
  9. Hermansson Jrgen L. E. (Huddinge SEX), Separation material, methods of producing a separation material and use of orosomucoid, functional analogs thereto or de.
  10. Someno Tetsuya (Oomiya JPX) Kato Kazuo (Urawa JPX) Saino Tetsushi (Yono JPX) Ishii Shinichi (Sapporo JPX) Takeuchi Tomio (Tokyo JPX) Umezawa Hamao (Tokyo JPX), Water-insoluble biospecific absorbent containing argininal derivative.

이 특허를 인용한 특허 (53)

  1. Zuckermann, Ronald N.; Beausoleil, Eric; Wachowicz, Matthew; Kothakota, Srinivas, Biological sample component purification and differential display.
  2. Hodges Robert S.,CAX ; Irvin Randall T.,CAX ; Holm Arne,DKX ; Wong Wah Y.,CAX ; Sheth Hasmukh B.,CAX ; Husband Devon L.,CAX, Combinational library composition and method.
  3. Waldman, Scott A.; Park, Jason; Schulz, Stephanie, Compositions and methods for identifying and targeting cancer cells of alimentary canal origin.
  4. Waldman, Scott A.; Park, Jason; Schulz, Stephanie, Compositions and methods for identifying and targeting cancer cells of alimentary canal origin.
  5. Waldman, Scott A.; Park, Jason; Schulz, Stephanie, Compositions and methods for identifying and targeting cancer cells of alimentary canal origin.
  6. Waldman, Scott A.; Park, Jason; Schulz, Stephanie, Compositions and methods for identifying and targeting cancer cells of alimentary canal origin.
  7. Waldman Scott A. ; Pearlman Joshua M. ; Barber Michael T. ; Schulz Stephanie ; Parkinson Scott J., Compositions that specifically bind to colorectal cancer cells and methods of using the same.
  8. Waldman,Scott A.; Pearlman,Joshua M.; Barber,Michael T.; Schulz,Stephanie; Parkinson,Scott J., Compositions that specifically bind to colorectal cancer cells and methods of using the same.
  9. Waldman,Scott A.; Pearlman,Joshua M.; Barber,Michael T.; Schulz,Stephanie; Parkinson,Scott J., Compositions that specifically bind to colorectal cancer cells and methods of using the same.
  10. Shepard, H. Michael; Chan, Ming Fai; Groziak, Michael P., Enzyme catalyzed therapeutic activation.
  11. Shepard, H. Michael; Groziak, Michael P., Enzyme catalyzed therapeutic agents.
  12. Shepard, H. Michael; Chan, Ming Fai; Groziak, Michael P., Enzyme catalyzed therapeutic compounds.
  13. Kauvar Lawrence M. (San Francisco CA) Lyttle Matthew H. (Point Reyes Station CA), Glutathione analogs and paralog panels comprising glutathione mimics.
  14. Kauvar Lawrence M. (San Francisco CA) Lyttle Matthew H. (Point Reyes Station CA), Glutathione analogs and paralog panels comprising glutathione mimics.
  15. Kauvar Lawrence M. ; Lyttle Matthew H., Glutathione analogs and paralog panels comprising glutathione mimics.
  16. Kauvar Lawrence M. ; Lyttle Matthew H., Glutathione analogs as reagents.
  17. Pantoliano,Michael W; Salemme,Francis R; Carver, Jr.,Theodore E, High throughput method for functionally classifying proteins identified using a genomics approach.
  18. Pieper, Rembert; Anderson, N. Leigh, Immunosubtraction method.
  19. Kauvar Lawrence M. ; Morgan Amy S. ; Lyttle Matthew H. ; Borch Richard F., Metabolic effects of certain glutathione analogs.
  20. Woods ; Jr. Virgil L., Method for characterization of the fine structure of protein binding sites.
  21. Woods ; Jr. Virgil L. (San Diego CA), Method for characterization of the fine structure of protein binding sites.
  22. Geysen Hendrik Mario,AUX, Method for the use and synthesis of peptides.
  23. Kauvar Lawrence M. (San Francisco CA), Method to identify analyte-binding ligands.
  24. Kauvar Lawrence M. (San Francisco CA) Villar Hugo O. (Newark CA), Method to identify binding partners.
  25. Woods ; Jr. Virgil L., Methods for the high-resolution identification of solvent-accessible amide hydrogens in polypeptides or proteins and for characterization of the fine structure of protein binding sites.
  26. Woods, Jr., Virgil L., Methods for the high-resolution identification of solvent-accessible amide hydrogens in protein binding sites.
  27. Shepard,H. Michael, Methods for treating therapy-resistant tumors.
  28. Weinberg David ; Waldman Scott A. ; Barber Michael T. ; Biswas Sanjoy, Methods of identifying and detecting pancreatic cancer.
  29. Waldman, Scott A.; Park, Jason; Schulz, Stephanie, Methods of screening and diagnosing esophageal cancer by determining guanylin cyclase C expression.
  30. Waldman Scott A., Methods of treating metastatic colorectal cancer with ST receptor binding compounds.
  31. Waldman, Scott A.; Pearlman, Joshua M.; Barber, Michael T.; Schulz, Stephanie; Parkinson, Scott J.; Prawer, Scott, Methods of using CRCA-1 as a stomach and esophageal cancer marker.
  32. Charych,Deborah; Beausoleil,Eric; Zuckermann,Ronald N., Microarrays on mirrored substrates for performing proteomic analyses.
  33. Pantoliano, Michael W.; Petrella, Eugenio C.; Salemme, F. Raymond; Springer, Barry A., Microplate thermal shift assay for ligand development using 5-(4"dimethylaminophenyl)-2-(4'-phenyl)oxazole derivative fluorescent dyes.
  34. Shepard,H. Michael; Vaino,Andrew Rein; Lehsten,Danielle M., Phosphoramidate compounds and methods of use.
  35. Charych,Deborah; Zuckermann,Ronald N., Protein microarrays on mirrored surfaces for performing proteomic analyses.
  36. Hutchens,T. William; Yip,Tai Tung, Retentate chromatography and protein chip arrays with applications in biology.
  37. Hutchens, T. William; Yip, Tai Tung, Retentate chromatography and protein chip arrays with applications in biology and medicine.
  38. Hutchens, T. William; Yip, Tai-Tung, Retentate chromatography and protein chip arrays with applications in biology and medicine.
  39. Hutchens, T. William; Yip, Tai-Tung, Retentate chromatography and protein chip arrays with applications in biology and medicine.
  40. Hutchens, T. William; Yip, Tai-Tung, Retentate chromatography and protein chip arrays with applications in biology and medicine.
  41. Hutchens, T. William; Yip, Tai-Tung, Retentate chromatography and protein chip arrays with applications in biology and medicine.
  42. Hutchens,T. William; Yip,Tai Tung, Retentate chromatography and protein chip arrays with applications in biology and medicine.
  43. Hutchens,T. William; Yip,Tai Tung, Retentate chromatography and protein chip arrays with applications in biology and medicine.
  44. Hutchens,T. William; Yip,Tai Tung, Retentate chromatography and protein chip arrays with applications in biology and medicine.
  45. Hutchens, T. William; Yip, Tai-Tung, Retentate chromatography—profiling with biospecific interaction adsorbents.
  46. Waldman, Scott A., ST receptor binding compounds and methods of using the same.
  47. Kauvar Lawrence M., Sorbent families.
  48. Kauvar Lawrence M. (San Francisco CA), Sorbent families.
  49. Andersson Karl,SEX ; Hamalainen Markku,SEX ; Malmqvist Magnus,SEX ; Roos H.ang.kan E.,SEX, Surface regeneration of biosensors and characterization of biomolecules associated therewith.
  50. Blume Arthur J., Target specific screens and their use for discovering small organic molecular pharmacophores.
  51. Kauvar Lawrence M. ; Lyttle Matthew H. ; Satyam Apparao, Urethane mediated, GST specific molecular release systems.
  52. Waldman, Scott A.; Pitari, Giovanni Mario; Park, Jason; Schulz, Stephanie; Wolfe, Henry R.; Lubbe, Wilhelm, Use of GCC ligands.
  53. Hutchens T. William ; Yip Tai-Tung, Use of retentate chromatography to generate difference maps.
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