초록 ▼

A good tissue-affinity and lack of antigenicity are required for the collagen used as the carrier of BMP. Conventional collagens have these properties only insufficiently. When the tyrosine content is below 2 residues/1000 residues, then the above properties of such collagens are good. Moreover, col

A good tissue-affinity and lack of antigenicity are required for the collagen used as the carrier of BMP. Conventional collagens have these properties only insufficiently. When the tyrosine content is below 2 residues/1000 residues, then the above properties of such collagens are good. Moreover, collagens excelling in the above properties can be readily obtained by using proteolytic enzymes.

대표청구항 ▼

Collagen for use as a carrier of bone morphogenic protein for osteogenesis which is a tissue-affinitive Type I collagen obtained from animals characterized by a tyrosine content of 1.5 residues/1000 residues or less, a minimum serine content of 10.0 residues/1000 residues, an isoelectric point of 7

Collagen for use as a carrier of bone morphogenic protein for osteogenesis which is a tissue-affinitive Type I collagen obtained from animals characterized by a tyrosine content of 1.5 residues/1000 residues or less, a minimum serine content of 10.0 residues/1000 residues, an isoelectric point of 7 or higher, and which is substantially free of aggregates.