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Polylactide compositions 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-009/14
  • A61K-013/00
출원번호 US-0438123 (1989-11-20)
발명자 / 주소
  • Loomis Gary L. (Drexel Hill PA) Murdoch Joseph R. (Wilmington DE)
출원인 / 주소
  • E. I. Du Pont de Nemours and Company (Wilmington DE 02)
인용정보 피인용 횟수 : 80  인용 특허 : 11

초록

Systems for delivery of biologically active materials employing novel polylactide composition containing segments of poly(R-lactide) interlocked with segments of poly(S-lactide) as the carrier.

대표청구항

A system for controlled delivery of biologically active ingredients wherein the ingredients contained in a polymeric composition comprising segments of poly(R-lactide) interlocked with segments of poly(S-lactide).

이 특허에 인용된 특허 (11)

  1. Nyilas Emery (Austin TX) Chiu Tin-Ho (Reading MA), Bioresorbable polyesters and polyester composites.
  2. Hutchinson Francis G. (Lymm GBX), Continuous release pharmaceutical compositions.
  3. Yolles Seymour (Newark DE), Controlled release of anticancer agents from biodegradable polymers.
  4. Kent John S. (Cupertino CA) Lewis Danny H. (Birmingham AL) Sanders Lynda M. (Palo Alto CA) Tice Thomas R. (Birmingham AL), Microencapsulation of water soluble active polypeptides.
  5. Lange Wolfgang (Obernburg DEX), Microporous polylactide powders and a process for their preparation.
  6. Vert Michel (Deville-les-Rouen FRX) Chabot Francois (Rouen FRX) Leray Jean (Sevres FRX) Christel Pascal (Paris FRX), New prosthesis parts, their preparation and their application.
  7. Loomis Gary L. (Drexel Hill PA) Murdoch Joseph R. (Wilmington DE), Polylactide compositions.
  8. Murdoch Joseph R. (Wilmington DE) Loomis Gary L. (Drexel Hill PA), Polylactide compositions.
  9. Murdoch Joseph R. (Wilmington DE) Loomis Gary L. (Drexel Hill PA), Polylactide compositions.
  10. Murdoch Joseph R. (Wilmington DE) Loomis Gary L. (Drexel Hill PA), Polylactide compositions.
  11. Wise Donald L. (Belmont MA), Sustained release of pharmaceuticals from polyester matrices.

이 특허를 인용한 특허 (80)

  1. Chakravarty, Jayant; Topolkaraev, Vasily A.; Ellis, Cliff J., Absorbent articles having biodegradable nonwoven webs.
  2. Dunn Richard L. ; Yewey Gerald L. ; Southard Jeffrey L. ; Urheim John E., Adjunctive polymer system for use with medical device.
  3. Coady, Daniel Joseph; Fukushima, Kazuki; Hedrick, James Lupton; Yang, Yi Yan, Antimicrobial compositions, methods of preparation thereof, and uses thereof.
  4. Tipton Arthur J. (Birmingham AL) Fujita Shawn M. (Amsterdam NLX) Dunn Richard L. (Fort Collins CO), Biodegradable film dressing and method for its formation.
  5. Alan M. Polson ; Deryl D. Swanbom ; Richard L. Dunn ; Charles P. Cox ; Richard L. Norton ; Bryan K. Lowe ; Kenneth S. Peterson, Biodegradable implant precursor.
  6. Tipton Arthur J. ; Fujita Shawn M. ; Dunn Richard L., Biodegradable in situ forming film dressing.
  7. Dunn Richard L. ; English James P. ; Cowsar Donald R. ; Vanderbilt David D., Biodegradable in-situ forming implants and methods of producing the same.
  8. Dunn Richard L. ; English James P. ; Cowsar Donald R. ; Vanderbilt David P., Biodegradable in-situ forming implants and methods of producing the same.
  9. Belcheva, Nadya; Stopek, Joshua, Biodegradable materials for orthopedic devices based on polymer stereocomplexes.
  10. Richard L. Dunn ; James P. English ; Donald R. Cowsar ; David P. Vanderbilt, Biogradable in-situ forming implants and methods of producing the same.
  11. Eaton, Gerald B.; Trainor, Patrick, Bulk polymerization reactor methods.
  12. Coady, Daniel J.; Engler, Amanda C.; Fukushima, Kazuki; Hedrick, James L.; Tan, Jeremy P. K.; Yang, Yi Yan, Cationic polymers for antimicrobial applications and delivery of bioactive materials.
  13. Coady, Daniel Joseph; Engler, Amanda Catherine; Fukushima, Kazuki; Hedrick, James Lupton; Tan, Jeremy Pang Kern; Yang, Yi Yan, Cationic polymers for antimicrobial applications and delivery of bioactive materials.
  14. Lee Hye-Jung ; Johnson OluFunmi L. ; Zale Stephen E. ; Tracy Mark A., Composition and method using solid-phase particles for sustained in vivo release of a biologically active agent.
  15. Johnson OluFunmi Lily (Cambridge MA) Ganmukhi Medha M. (Wexford PA) Bernstein Howard (Cambridge MA) Auer Henry (Belmont MA) Khan M. Amin (Dowington PA), Composition for sustained release of human growth hormone.
  16. Johnson OluFunmi Lily ; Ganmukhi Medha M. ; Bernstein Howard ; Auer Henry ; Khan M. Amin, Composition for sustained release of human growth hormone.
  17. Johnson OluFunmi Lily ; Ganmukhi Medha M. ; Bernstein Howard ; Auer Henry ; Khan M. Amin, Composition for sustained release of human growth hormone.
  18. OluFunmi Lily Johnson ; Medha M. Ganmukhi ; Howard Bernstein ; Henry Auer ; M. Amin Khan, Composition for sustained release of human growth hormone.
  19. Zale Stephen E. (Hopkington MA) Burke Paul A. (Medford MA) Bernstein Howard (Cambridge MA) Brickner Avram (Brookline MA), Composition for sustained release of non-aggregated erythropoietin.
  20. Zale Stephen E. ; Burke Paul A. ; Bernstein Howard ; Brickner Avram, Composition for sustained release of non-aggregated erythropoietin.
  21. Gruber Patrick R. (St. Paul MN) Hall Eric S. (Crystal MN) Kolstad Jeffrey J. (Wayzata MN) Iwen Matthew L. (Minneapolis MN) Benson Richard D. (Long Lake MN) Borchardt Ronald L. (Eden Prairie MN), Continuous process for manufacture of a purified lactide.
  22. Gruber Patrick Richard ; Hall Eric Stanley ; Kolstad Jeffrey John ; Iwen Matthew Lee ; Benson Richard Douglas ; Borchardt Ronald Leo, Continuous process for manufacture of lactide polymers with controlled optical purity.
  23. Gruber Patrick Richard ; Hall Eric Stanley ; Kolstad Jeffrey John ; Iwen Matthew Lee ; Benson Richard Douglas ; Borchardt Ronald Leo, Continuous process for manufacture of lactide polymers with controlled optical purity.
  24. Gruber Patrick Richard ; Hall Eric Stanley ; Kolstad Jeffrey John ; Iwen Matthew Lee ; Benson Richard Douglas ; Borchardt Ronald Leo, Continuous process for the manufacture of lactide and lactide polymers.
  25. Chandrashekar Bhagya L. ; Zhou Mingxing ; Jarr Eileen M. ; Dunn Richard L., Controlled release liquid delivery compositions with low initial drug burst.
  26. Dunn, Richard L.; Yarborough, Cody L., Coupling syringe system and methods for obtaining a mixed composition.
  27. Bigg Donald M. ; Sinclair Richard G. ; Lipinsky Edward S. ; Litchfield John H. ; Allen Billy R., Degradation control of environmentally degradable disposable materials.
  28. Dunn,Richard L., Emulsions for in-situ delivery systems.
  29. Sinclair Richard G. ; Lipinsky Edward S. ; Browning James D. ; Bigg Donald ; Rogers Thomas A., End use applications of biodegradable polymers.
  30. Horacek H. Joseph, Extended release clonidine formulation (capsule).
  31. Horacek H. Joseph, Extended release clonidine formulation (tablet).
  32. Horacek, Henry Joseph; He, Min Michael; Khayrallah, Moise A., Extended release formulation and method of treating adrenergic dysregulation.
  33. Cady,Susan Mancini; Macar,Claude; Gibson,John W., Extended release growth promoting two component composition.
  34. Brodbeck Kevin J. ; Gaynor-Duarte Ann T. ; Shen Theodore Tao-Ian, Gel composition and methods.
  35. Brodbeck, Kevin J.; Gaynor-Duarte, Ann T.; Shen, Theodore Tao-Ian, Gel composition and methods.
  36. Kevin J. Brodbeck ; Ann T. Gaynor-Duarte ; Theodore Tao-Ian Shen, Gel composition and methods.
  37. Brodbeck Kevin J. ; Shen Theodore T., Injectable depot gel composition and method of preparing the composition.
  38. Tice Thomas R. ; Staas Jay K. ; Ferrell Teresa M., Injectable naltrexone microsphere compositions and their use in reducing consumption of heroin and alcohol.
  39. Yewey Gerald L. ; Krinick Nancy L. ; Dunn Richard L. ; Radomsky Michael L. ; Brouwer Gerbrand ; Tipton Arthur J., Liquid delivery compositions.
  40. Yewey Gerald L. ; Krinick Nancy L. ; Dunn Richard L. ; Radomsky Michael L. ; Brouwer Gerbrand ; Tipton Arthur J., Liquid delivery compositions.
  41. Gruber Patrick R. (St. Paul MN) Kolstad Jeffrey J. (Wayzata MN) Ryan Christopher M. (Dayton MN) Hall Eric S. (Crystal MN) Eichen Conn Robin S. (Minneapolis MN), Melt-stable amorphous lactide polymer film and process for manufacture thereof.
  42. Gruber Patrick Richard ; Kolstad Jeffrey John ; Ryan Christopher M. ; Hall Eric Stanley ; Eichen Conn Robin Sue, Melt-stable amorphous lactide polymer film and process for manufacture thereof.
  43. Gruber Patrick Richard ; Kolstad Jeffrey John ; Ryan Christopher M. ; Hall Eric Stanley ; Eichen Conn Robin Sue, Melt-stable amorphous lactide polymer film and process for manufacture thereof.
  44. Gruber Patrick Richard ; Kolstad Jeffrey John ; Hall Eric Stanley ; Eichen Conn Robin Sue ; Ryan Christopher M., Melt-stable lactide polymer composition and process for manufacture thereof.
  45. Gruber Patrick Richard ; Kolstad Jeffrey John ; Hall Eric Stanley ; Eichen Conn Robin Sue ; Ryan Christopher M., Melt-stable lactide polymer composition and process for manufacture thereof.
  46. Gruber Patrick Richard ; Kolstad Jeffrey John ; Hall Eric Stanley ; Eichen Conn Robin Sue ; Ryan Christopher M., Melt-stable lactide polymer composition and process for manufacture thereof.
  47. Gruber Patrick R. ; Kolstad Jeffrey J. ; Ryan Christopher M. ; Eichen Conn Robin S. ; Hall Eric S., Melt-stable lactide polymer nonwoven fabric and process for manufacture thereof.
  48. Patrick R. Gruber ; Jeffrey J. Kolstad ; Christopher M. Ryan ; Robin S. Eichen Conn ; Eric S. Hall, Melt-stable lactide polymer nonwoven fabric and process for manufacture thereof.
  49. Gruber Patrick Richard ; Kolstad Jeffrey John ; Ryan Christopher M. ; Hall Eric Stanley ; Eichen Conn Robin Sue, Melt-stable semi-crystalline lactide polymer film and process for manufacture thereof.
  50. Gruber Patrick Richard ; Kolstad Jeffrey John ; Ryan Christopher M. ; Hall Eric Stanley ; Eichen Conn Robin Sue, Melt-stable semi-crystalline lactide polymer film and process for manufacture thereof.
  51. Gruber Patrick Richard ; Kolstad Jeffrey John ; Ryan Christopher M. ; Hall Eric Stanley ; Eichen Conn Robin Sue, Melt-stable semi-crystalline lactide polymer film and process for manufacture thereof.
  52. Polson Alan M. ; Swanbom Deryl D. ; Dunn Richard L. ; Cox Charles P. ; Norton Richard L. ; Lowe Bryan K. ; Peterson Kenneth S., Method and composition for treating a bone tissue defect.
  53. Kim, Soo Hyun; Jung, Young Mee; Kim, Sang-Heon; Purba, Purnama, Method for preparing biodegradable polymer stereocomplexes using a supercritical fluid-organic solvent system and stereocomplexes prepared by the same.
  54. Staas, Jay K.; Tice, Thomas R.; Hudson, Bruce W.; Tipton, Arthur J., Methods for manufacturing delivery devices and devices thereof.
  55. Soane, David S.; Tagge, Christopher D., Mixed organic and inorganic composites with intermingled facial layers.
  56. Bernstein Howard ; Zhang Yan ; Khan M. Amin ; Tracy Mark A., Modulated release from biocompatible polymers.
  57. Bernstein, Howard; Zhang, Yan; Khan, M. Amin; Tracy, Mark A., Modulated release from biocompatible polymers.
  58. Howard Bernstein ; Yan Zhang ; M. Amin Khan ; Mark A. Tracy, Modulated release from biocompatible polymers.
  59. Gruber Patrick Richard ; Kolstad Jeffrey John ; Ryan Christopher M. ; Hall Eric Stanley ; Eichen Conn Robin Sue, Paper having a melt-stable lactide polymer coating and process for manufacture thereof.
  60. Dudley, Robert E.; Drouin, Dominique, Pharmaceutical composition and method for treating hypogonadism.
  61. Dudley, Robert E.; Drouin, Dominique, Pharmaceutical composition and method for treating hypogonadism.
  62. Dudley, Robert E.; Kottayil, S. George; Palatchi, Olivier, Pharmaceutical composition and method for treating hypogonadism.
  63. Benson, Richard Douglas, Polylactic acid stereocomplex compositions and methods for making and using same.
  64. Totakura Nagabhushanam (North Haven CT) Shalaby Shalaby W. (Anderson SC), Polymeric composition.
  65. Biggs, Danielle; Nettles, Heather, Process for preparing microparticles having a low residual solvent volume.
  66. Warren E. Jaworowicz ; James I. Wright, Process for the preparation of polymer-based sustained release compositions.
  67. Jurgens Christian (Hochallee 19 2000 Hamburg 13 DEX), Resorbable biocompatible copolymers and their use.
  68. Abraham J. Domb IL; Zeev Zehavi IL, Stereocomplex polymeric carriers for drug delivery.
  69. Yarborough, Cody L; Duncan, Michael R.; Norton, Richard L.; Bawa, Rajan; Madril, Dominic G.; Barrett, Christopher J., Stoppering method to maintain sterility.
  70. Malladi, Ramana; Miller, Jodi, Testosterone gel and method of use.
  71. Malladi, Ramana; Miller, Jodi, Testosterone gel and method of use.
  72. Malladi, Ramana; Stahlman, Jodi, Testosterone gel and method of use.
  73. Malladi, Ramana; Stahlman, Jodi, Testosterone gel and method of use.
  74. Malladi, Ramana; Stahlman, Jodi, Testosterone gel and method of use.
  75. Malladi, Ramana; Stahlman, Jodi, Testosterone gel and method of use.
  76. Malladi, Ramana; Stahlman, Jodi, Testosterone gel and method of use.
  77. Malladi, Ramana; Stahlman, Jodi, Testosterone gel and method of use.
  78. Harvan Donald J. ; Pfaender Frederic K., Time release delivery system.
  79. Gibson, John W.; Tipton, Arthur J.; Holl, Richard J.; Meador, Stacey, Zero-order prolonged release coaxial implants.
  80. Gibson, John W.; Tipton, Arthur J.; Holl, Richard; Meador, Stacey, Zero-order prolonged release coaxial implants.
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