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Sustained release dosage form 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-039/00
  • A61K-039/35
  • A61K-039/36
  • A61K-009/14
출원번호 US-0308225 (1989-02-08)
발명자 / 주소
  • Silvestri Loui J. (Miramar FL) Pyle H. Ruth (Ft. Lauderdale FL)
출원인 / 주소
  • BioSearch, Inc. (Pembroke Pines FL 02)
인용정보 피인용 횟수 : 13  인용 특허 : 42

초록 ▼

A multiphasic sustained release injectable delivery system is provided, as well as a method for treating humans and other mammals with that multiphasic sustained release system. The multiphasic sustained release system comprises prolonged, controlled delivery of microencapsulated allergen extract co

대표청구항 ▼

A multiphasic sustained release injectable delivery system for prolonged, controlled delivery of microencapsulated allergen extract comprising allergen extract encapsulated in microcapsules of bioerodible encapsulating polymer, which permits a sustained, multiphasic release of said allergen extract,

이 특허에 인용된 특허 (42)

  1. Himmelstein Kenneth J. (Lawrence KS) Higuchi Takeru (Lawrence KS), Acid anhydrides as rate controlling agent for the erosion of polymers which latter polymers have beneficial substances d.
    상세보기
  2. Lee Weng Y. (Winnipeg CAX) Sehon Alec (Winnipeg CAX), Allergen-containing substances.
    상세보기
  3. Garman Andrew J. (Betchworth GB2) Wheeler Alan (South Holmwood GB2), Anti-allergic compositions and their use.
    상세보기
  4. Malley Arthur (Beaverton OR), Antigen-protein complex for blocking allergic reactions.
    상세보기
  5. Malley Arthur (Beaverton OR), Antigen-protein complex for blocking allergic reactions.
    상세보기
  6. Bichon Daniel (Gaillard FRX), Biodegradable polypeptide and its use for the gradual release of drugs.
    상세보기
  7. Couvreur Patrick (8 ; Avenue de la Foret 1970 Wezembeek-Oppem BEX) Roland Michel (38 ; rue Tomberg 1150 Bruxelles BEX) Speiser Peter (26Wassbergerstrasse 8127 Forch CHX), Biodegradable submicroscopic particles containing a biologically active substance and compositions containing them.
    상세보기
  8. Sidman Kenneth R. (Wayland MA), Biodegradable, implantable drug delivery device, and process for preparing and using the same.
    상세보기
  9. Churchill Jeffrey R. (Northwich GBX) Hutchinson Francis G. (Lymm GBX), Continuous release formulations.
    상세보기
  10. Hutchinson Francis G. (Lymm GBX), Continuous release pharmaceutical compositions.
    상세보기
  11. Ludwig Nelson H. (Greenfield IN) Ose Earl E. (Greenfield IN), Controlled release formulations and method of treatment.
    상세보기
  12. Schrder Ulf (Fagottgrnden 11 B S-223 68 Lund SEX), Crystallized carbohydrate matrix for biologically active substances, a process of preparing said matrix, and the use the.
    상세보기
  13. Choi ; Nam Sok ; Heller ; Jorge, Drug delivery devices manufactured from poly(orthoesters) and poly(orthocarbonates).
    상세보기
  14. Snipes Wallace C. (Pine Grove Mills PA), Erodible matrix for sustained release bioactive composition.
    상세보기
  15. Marsh David G. (11420 Harford Rd. Baltimore MD 21057), Formalinized allergen-containing substances and production thereof.
    상세보기
  16. Patterson Roy (Wilmette IL) McIntire Floyd C. (Denver CO), Glutaraldehyde polymerized ragweed antigen E preparation for treatment of allergic patients sensitive to ragweed pollen.
    상세보기
  17. Domb Abraham J. (Brookline MA) Langer Robert S. (Somerville MA), High molecular weight polyanhydride and preparation thereof.
    상세보기
  18. Katz David H. (La Jolla CA), Immunochemical conjugates: method and composition.
    상세보기
  19. Katz David H. (La Jolla CA), Immunochemical conjugates: method and composition.
    상세보기
  20. Katz David H. (La Jolla CA), Immunochemical conjugates: method and composition.
    상세보기
  21. Katz David H. (La Jolla CA), Induction of immunological tolerance.
    상세보기
  22. Amkraut Alfred A. (Palo Alto CA) Martins Agusto B. (Palo Alto CA), Method for administering immunopotentiator.
    상세보기
  23. Sadek Safik E. (Wayland MA), Methods of improving control of release rates and products useful in same.
    상세보기
  24. Speiser Peter (Forch CH) Birrenbach Gerd (Aesch CH), Microcapsules in the nanometric range and a method for their production.
    상세보기
  25. Kent John S. (Cupertino CA) Lewis Danny H. (Birmingham AL) Sanders Lynda M. (Palo Alto CA) Tice Thomas R. (Birmingham AL), Microencapsulation of water soluble active polypeptides.
    상세보기
  26. Malley Arthur (Beaverton OR), Modified grass pollen antigens.
    상세보기
  27. Malley Arthur (Beaverton OR), Modified grass pollen antigens.
    상세보기
  28. Kohn Joachim (Brookline MA) Langer Robert S. (Somerville MA), Non-peptide polyamino acid bioerodible polymers.
    상세보기
  29. Overell Brain G. (North Holmwood GB2), Pharmaceutical compositions.
    상세보기
  30. Tanaka Motoaki (Saitama JPX) Ogawa Yasuaki (Osaka JPX) Miyagawa Tsutomu (Saitama JPX) Watanabe Toshio (Saitama JPX), Polymer and its production.
    상세보기
  31. Michael J. Gabriel (418 Chisholm Trail Cincinnati OH 45215) Pesce Amadeo J. (5769 Whitechapel Cincinnati OH 45236), Polypeptide active immunosuppressant fraction.
    상세보기
  32. Michael Jacob G. (418 Chisholm Trail Cincinnati OH 45215) Pesce Amadeo J. (5769 White Chapel Dr. Cincinnati OH 45236), Polypeptide active pollen immunosuppressant fraction.
    상세보기
  33. Patterson Roy (3109 Country La. Wilmette IL 60091) McIntire Floyd C. (7780 E. Cornell Ave. Denver CO 80231), Preparation for treatment of allergic patients sensitive to ragweed pollen.
    상세보기
  34. De Luca Patrick P. (Lexington KY) Rypacek Frantisek (Leckova CZX), Preparation of biodegradable microspheres useful as carriers for macromolecules.
    상세보기
  35. Couvreur Patrick (Wezembeek-Oppem BEX) Roland Michel (Brussels BEX) Speiser Peter (Forch CHX), Process for preparing biodegradable submicroscopic particles containing a biologically active substance and their use.
    상세보기
  36. Green ; Geoffrey ; Overell ; Brian George ; Hart ; Anthony Phillip, Process for preparing injectable desensitizing compositions and products thereof in microparticle form.
    상세보기
  37. Marsh David G. (Overlea MD), Production of aldehyde-treated allergen-containing substances.
    상세보기
  38. Choi ; Nam S. ; Heller ; Jorge, Structured orthoester and orthocarbonate drug delivery devices.
    상세보기
  39. Wise Donald L. (Belmont MA), Sustained release of pharmaceuticals from polyester matrices.
    상세보기
  40. Bawa Rajan (Fairport NY) Deichert William G. (Macedon NY), Sustained-release formulation containing an amino acid polymer with a lower alkyl (C1-C4) po.
    상세보기
  41. Folkman Moses J. (18 Chathman Cir. Brookline MA 02146) Langer ; Jr. Robert S. (1200 Commonwealth ; Apt. 2 Allston MA 02134), Systems for the controlled release of macromolecules.
    상세보기
  42. Folkman Moses J. (Brookline MA) Langer ; Jr. Robert S. (Allston MA), Systems for the controlled release of macromolecules.
    상세보기

이 특허를 인용한 특허 (13)

  1. Tice Thomas R. ; Gilley Richard M. ; Eldridge John H. ; Staas Jay K., Composition for delivering bioactive agents for immune response and its preparation.
    상세보기
  2. Cleland, Jeffrey L.; Lim, Amy; Powell, Michael Frank, Compositions for microencapsulation of antigens for use as vaccines.
    상세보기
  3. Kipper, Matthew J.; Narasimhan, Balaji; Wilson, Jennifer H.; Wannemuehler, Michael J., Controlled-release immunogenic formulations to modulate immune response.
    상세보기
  4. Kipper, Matthew J.; Narasimhan, Balaji; Wilson, Jennifer H.; Wannemuehler, Michael J., Controlled-release immunogenic formulations to modulate immune response.
    상세보기
  5. Lewis Danny H. (Hartselle AL), Growth promoters for animals.
    상세보기
  6. Aebischer Patrick,CHX ; Deglon Nicole,CHX ; Regulier Etienne,CHX ; Rinsch Christopher,CHX, Hypoxia responsive EPO producing cells.
    상세보기
  7. Tice Thomas R. ; Gilley Richard M. ; Eldridge John H. ; Staas Jay K., Method for delivering bioactive agents into and through the mucosally-associated lymphoid tissue and controlling their r.
    상세보기
  8. Tice Thomas R. ; Gilley Richard M. ; Eldridge John H. ; Staas Jay K., Method for delivering bioactive agents into and through the mucosally-associated lymphoid tissues and controlling their.
    상세보기
  9. Tice Thomas R. ; Gilley Richard M. ; Eldridge John H. ; Staas Jay K., Method for delivering bioactive agents into and through the mucosally-associated lymphoid tissues and controlling their.
    상세보기
  10. Cleland Jeffrey L. ; Jones Andrew J. S. ; Powell Michael Frank, Method for drying microspheres.
    상세보기
  11. Tice Thomas R. ; Gilley Richard M. ; Eldridge John H. ; Staas Jay K., Method for oral or rectal delivery of microencapsulated vaccines and compositions therefor.
    상세보기
  12. Dolovich Jerry,CAX ; Ulrich J. Terry ; Marshall Jean S.,CAX, Methods of treating type I hypersensitivity using monophosphoryl lipid A.
    상세보기
  13. Laurencin Cato T. ; El-Amin Saadiq ; Ambrosio Archel M. A. ; Pucher Shawn R. ; Allcock Harry R., Poly(organophosphazene) matrices for bone replacement.
    상세보기

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