초록 ▼

A composition comprising a flexible backing for a transdermal drug preparation with a water vapor transmission rate about equal to or in excess of that of ethylene vinyl alcohol copolymer, namely equal to or in excess of, at one mil thickness, of about 2 to 4 grams and more preferably in excess of 6

A composition comprising a flexible backing for a transdermal drug preparation with a water vapor transmission rate about equal to or in excess of that of ethylene vinyl alcohol copolymer, namely equal to or in excess of, at one mil thickness, of about 2 to 4 grams and more preferably in excess of 6 grams per 24 hours per 100 square inches at 40°C. and 90% relative humidity and an oxygen transmission rate equal to or less than ethylene vinyl alcohol copolymer, namely at one mil thickness equal to or less than about 0.01 to 0.1 cubic centimeters per 100 square inches measured over 24 hours at 1 atmospheric pressure, 20°C. and 65% relative humidity.

대표청구항 ▼

A composition, which comprises: a pharmacologically active agent in a transdermal carrier having two surfaces, one surface being adapted for application to the skin and a second surface opposed thereto; and a backing of at least a first layer of a plastic film for said second surface of the carrier,

A composition, which comprises: a pharmacologically active agent in a transdermal carrier having two surfaces, one surface being adapted for application to the skin and a second surface opposed thereto; and a backing of at least a first layer of a plastic film for said second surface of the carrier, having a thickness from about 0.2 to 3 mils, and having a water vapor transmission rate at 1 mil thickness in excess of about 2 grams per 100 square inches per 24 hours, at 40°C. and 90% relative humidity and an oxygen transmission rate at 1 mil thickness equal to or less than 0.1 cubic centimeters per 100 square inches measured over 24 hours at 1 atmosphere of pressure, at 20°C. and 65% relative humidity, said backing having a first side facing the second surface of the transdermal carrier and a second side opposite thereto.